The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U INC COM USD0.001 | COM | 90214J101 | 168,688 | 3,010,135 | SH | DFND | 777,128 | 0 | 2,233,007 | ||
| ABIOMED INC | COM | 003654100 | 2,537 | 15,048 | SH | DFND | 3,582 | 0 | 11,466 | ||
| ABRAXAS PETE CORP | COM | 003830106 | 756 | 402,225 | SH | DFND | 48,408 | 0 | 353,817 | ||
| ACACIA COMMUNICATIONS INC COM | COM | 00401C108 | 66,217 | 1,405,876 | SH | DFND | 242,681 | 0 | 1,163,195 | ||
| ACADIA HEALTHCARE COMPANY INC COM | COM | 00404A109 | 6,228 | 130,392 | SH | DFND | 1,308 | 0 | 129,084 | ||
| ACADIA PHARMACEUTICALS INC COM | COM | 004225108 | 4,640 | 123,171 | SH | DFND | 21,487 | 0 | 101,684 | ||
| ACCELERATE DIAGNOSTICS INC COM USD0.001 | COM | 00430H102 | 890 | 39,641 | SH | DFND | 8,750 | 0 | 30,891 | ||
| ACTIVISION BLIZZARD INC COM | COM | 00507V109 | 113,135 | 1,753,752 | SH | DFND | 344,489 | 0 | 1,409,263 | ||
| ADESTO TECHNOLOGIES CORP COM | COM | 00687D101 | 13,001 | 1,656,129 | SH | DFND | 97,291 | 0 | 1,558,838 | ||
| ADOBE SYS INC | COM | 00724F101 | 80,093 | 536,886 | SH | DFND | 174,132 | 0 | 362,754 | ||
| ADVANCED MICRO DEVICES INC COM | COM | 007903107 | 361 | 28,323 | SH | DFND | 6,816 | 0 | 21,507 | ||
| ALASKA COMM SYS GRP INC | COM | 01167P101 | 3,274 | 1,442,269 | SH | DFND | 204,183 | 0 | 1,238,086 | ||
| ALIBABA GROUP HLDG LTD SPONSORED ADS | COM | 01609W102 | 78,517 | 454,618 | SH | DFND | 166,539 | 0 | 288,079 | ||
| ALIGN TECHNOLOGY INC COM | COM | 016255101 | 127,724 | 685,693 | SH | DFND | 82,697 | 0 | 602,996 | ||
| ALLEGIANT TRAVEL CO COM | COM | 01748X102 | 14,289 | 108,497 | SH | DFND | 8,119 | 0 | 100,378 | ||
| ALLERGAN PLC. COM USD0.0001 | COM | G0177J108 | 295 | 1,439 | SH | DFND | 42 | 0 | 1,397 | ||
| ALMOST FAMILY INC | COM | 020409108 | 12,771 | 237,816 | SH | DFND | 43,027 | 0 | 194,789 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 131,654 | 1,120,555 | SH | DFND | 300,127 | 0 | 820,428 | ||
| ALPHABET INC CAP STK CL A | COM | 02079K305 | 47,160 | 48,433 | SH | DFND | 4,182 | 0 | 44,251 | ||
| ALPHABET INC CAP STK CL C | COM | 02079K107 | 61,622 | 64,249 | SH | DFND | 7,458 | 0 | 56,791 | ||
| AMAZON.COM INC | COM | 023135106 | 435,259 | 452,758 | SH | DFND | 177,840 | 0 | 274,918 | ||
| AMBER ROAD INC COM USD0.001 | COM | 02318Y108 | 556 | 72,341 | SH | DFND | 7,099 | 0 | 65,242 | ||
| AMERICAN TOWER CORPORATION | COM | 03027X100 | 11,969 | 87,566 | SH | DFND | 8,583 | 0 | 78,983 | ||
| AMS AG NPV (BR) ISIN #AT0000A18XM4 SEDOL #BPF0548 | COM | A0400Q115 | 79 | 1,085 | SH | DFND | 95 | 0 | 990 | ||
| APACHE CORP | COM | 037411105 | 11,850 | 258,724 | SH | DFND | 27,140 | 0 | 231,584 | ||
| APPIAN CORP CL A | COM | 03782L101 | 6,995 | 245,773 | SH | DFND | 28,190 | 0 | 217,583 | ||
| APPLE INC | COM | 037833100 | 4,105 | 26,634 | SH | DFND | 6,268 | 0 | 20,366 | ||
| APPLIED MATERIALS INC | COM | 038222105 | 1,058 | 20,303 | SH | DFND | 7,772 | 0 | 12,531 | ||
| APPLIED OPTOELECTRONICS INC COM | COM | 03823U102 | 17,023 | 263,232 | SH | DFND | 28,607 | 0 | 234,625 | ||
| ARISTA NETWORKS INC COM USD0.0001 | COM | 040413106 | 110,806 | 584,389 | SH | DFND | 28,833 | 0 | 555,556 | ||
| ASV HLDGS INC COM | COM | 00215L104 | 9,598 | 1,180,515 | SH | DFND | 41,431 | 0 | 1,139,084 | ||
| AT HOME GROUP INC COM | COM | 04650Y100 | 1,882 | 82,409 | SH | DFND | 7,172 | 0 | 75,237 | ||
| ATHENAHEALTH INC DELAWARE | COM | 04685W103 | 350 | 2,817 | SH | DFND | 363 | 0 | 2,454 | ||
| ATHENEX INC COM | COM | 04685N103 | 1,559 | 89,026 | SH | DFND | 24,540 | 0 | 64,486 | ||
| ATKORE INTL GROUP INC COM | COM | 047649108 | 330 | 16,905 | SH | DFND | 14,639 | 0 | 2,266 | ||
| ATLASSIAN CORPORATION PLC COM USD0.1 CL A | COM | G06242104 | 17,452 | 496,497 | SH | DFND | 64,318 | 0 | 432,179 | ||
| AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV | COM | G06708104 | 5,898 | 1,120,012 | SH | DFND | 234,133 | 0 | 885,879 | ||
| AUTODESK INC COM | COM | 052769106 | 91,516 | 815,218 | SH | DFND | 133,941 | 0 | 681,277 | ||
| AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # | COM | 05462W109 | 582 | 15,085 | SH | DFND | 15,000 | 0 | 85 | ||
| AXOGEN INC COM | COM | 05463X106 | 10,914 | 564,038 | SH | DFND | 120,847 | 0 | 443,191 | ||
| AZUL SA SPON ADR EACH REP 3 PFD SHS | COM | 05501U106 | 145,071 | 5,284,922 | SH | DFND | 997,634 | 0 | 4,287,288 | ||
| BAIDU INC SPONS ADR REPR 0.10 ORD CLS A | COM | 056752108 | 11,901 | 48,049 | SH | DFND | 10,635 | 0 | 37,414 | ||
| BANCO MACRO S.A. ADR REP 10 CLS B SHS ARS1 | COM | 05961W105 | 94 | 804 | SH | DFND | 151 | 0 | 653 | ||
| BARCLAYS BK PLC IPATH S&P 500 VIX SHORT TERM FUTURES ETN NEW 201 | COM | 06746L422 | 15,351 | 391,706 | SH | DFND | 50,480 | 0 | 341,226 | ||
| BELLATRIX EXPLORATION LTD COM NPV ISIN #CA0783145075 SEDOL #BF23 | COM | 078314507 | 353 | 124,191 | SH | DFND | 21,771 | 0 | 102,420 | ||
| BERKLEY W R CORP | COM | 084423102 | 4,425 | 66,307 | SH | DFND | 17,940 | 0 | 48,367 | ||
| BERKSHIRE HATHAWAY INC DEL CL B NEW | COM | 084670702 | 37 | 200 | SH | DFND | 0 | 0 | 200 | ||
| BIOHAVEN PHARMACEUTICAL HLDG CO LTD COM NPV | COM | G11196105 | 2,790 | 74,637 | SH | DFND | 19,388 | 0 | 55,249 | ||
| BIOSCRIP INC | COM | 09069N108 | 43,352 | 15,764,337 | SH | DFND | 3,684,991 | 0 | 12,079,346 | ||
| BMC STK HLDGS INC COM | COM | 05591B109 | 491 | 23,000 | SH | DFND | 23,000 | 0 | 0 | ||
| BOINGO WIRELESS INC COM USD0.0001 | COM | 09739C102 | 11,390 | 532,971 | SH | DFND | 87,034 | 0 | 445,937 | ||
| BOOHOO.COM PLC ORD GBP0.01 ISIN #JE00BG6L7297 SEDOL #BG6L729 | COM | G6153P109 | 56 | 19,720 | SH | DFND | 3,870 | 0 | 15,850 | ||
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 1,342 | 45,996 | SH | DFND | 20,722 | 0 | 25,274 | ||
| BOX INC CL A | COM | 10316T104 | 12,940 | 669,781 | SH | DFND | 112,806 | 0 | 556,975 | ||
| BRIGHTCOVE INC COM USD0.001 | COM | 10921T101 | 219 | 30,387 | SH | DFND | 3,656 | 0 | 26,731 | ||
| BYD COMPANY LIMITED H CNY1 ISIN #CNE100000296 SEDOL #6536651 | COM | Y1023R104 | 37,511 | 4,044,000 | SH | DFND | 1,230,500 | 0 | 2,813,500 | ||
| C S X CORP | COM | 126408103 | 399 | 7,356 | SH | DFND | 191 | 0 | 7,165 | ||
| C&J ENERGY SVCS INC NEW COM | COM | 12674R100 | 212 | 7,058 | SH | DFND | 2,555 | 0 | 4,503 | ||
| CAESARS ENTMT CORP COM | COM | 127686103 | 1,626 | 121,829 | SH | DFND | 40,050 | 0 | 81,779 | ||
| CAMPING WORLD HLDGS INC CL A | COM | 13462K109 | 2,991 | 73,417 | SH | DFND | 24,521 | 0 | 48,896 | ||
| CANADA GOOSE HOLDINGS INC COM NPV SUB VTNG SHS ISIN #CA135086106 | COM | 135086106 | 490 | 23,854 | SH | DFND | 0 | 0 | 23,854 | ||
| CARDIOVASCULAR SYS INC DEL COM | COM | 141619106 | 330 | 11,738 | SH | DFND | 2,919 | 0 | 8,819 | ||
| CARL ZEISS MEDITEC AG NPV ISIN #DE0005313704 SEDOL #5922961 | COM | D14895102 | 863 | 16,581 | SH | DFND | 6,380 | 0 | 10,201 | ||
| CARROLS RESTAURANT GROUP INC COM | COM | 14574X104 | 8,634 | 792,096 | SH | DFND | 79,443 | 0 | 712,653 | ||
| CATAPULT GROUP INTERNATIONAL ISIN #AU000000CAT9 SEDOL #BTL0Y76 | COM | Q2159P101 | 232 | 227,862 | SH | DFND | 23,208 | 0 | 204,654 | ||
| CAVIUM INC COM | COM | 14964U108 | 29,174 | 442,428 | SH | DFND | 35,556 | 0 | 406,872 | ||
| CBS CORP NEW CL B | COM | 124857202 | 1,518 | 26,174 | SH | DFND | 5,598 | 0 | 20,576 | ||
| CHARTER COMMUNICATIONS INC NEW CL A | COM | 16119P108 | 217 | 596 | SH | DFND | 26 | 0 | 570 | ||
| CHEGG INC COM USD0.001 | COM | 163092109 | 104,517 | 7,042,911 | SH | DFND | 1,339,676 | 0 | 5,703,235 | ||
| CITIGROUP INC COM NEW | COM | 172967424 | 6,821 | 93,776 | SH | DFND | 16,496 | 0 | 77,280 | ||
| CLOUDERA INC COM | COM | 18914U100 | 1,912 | 115,036 | SH | DFND | 23,165 | 0 | 91,871 | ||
| COGENT COMMUNICATION HLDGS INC COM NEW | COM | 19239V302 | 350 | 7,152 | SH | DFND | 667 | 0 | 6,485 | ||
| COGNEX CORP COM | COM | 192422103 | 36,252 | 328,727 | SH | DFND | 113,362 | 0 | 215,365 | ||
| CONSTELLATION BRANDS INC CL A | COM | 21036P108 | 9,976 | 50,017 | SH | DFND | 4,648 | 0 | 45,369 | ||
| COVANTA HLDG CORP COM | COM | 22282E102 | 7,996 | 538,484 | SH | DFND | 92,364 | 0 | 446,120 | ||
| CRIMSON WINE GROUP COM USD0.01 | COM | 22662X100 | 220 | 20,452 | SH | DFND | 525 | 0 | 19,927 | ||
| DEERE & COMPANY | COM | 244199105 | 13 | 100 | SH | DFND | 0 | 0 | 100 | ||
| DELTA AIR LINES INC DEL COM NEW | COM | 247361702 | 3,957 | 82,058 | SH | DFND | 1,083 | 0 | 80,975 | ||
| DIRTT ENVIRONMENTAL SOLUT LTD COM ISIN #CA25490H1064 SEDOL #BH13 | COM | 25490H106 | 6,976 | 1,592,093 | SH | DFND | 394,235 | 0 | 1,197,858 | ||
| DOMINO S PIZZA ENTERPRISES L ISIN #AU000000DMP0 SEDOL #B07SFG7 | COM | Q32503106 | 11,378 | 316,475 | SH | DFND | 30,138 | 0 | 286,337 | ||
| ECO STIM ENERGY SOLUTIONS INC COM | COM | 27888D101 | 1,152 | 748,189 | SH | DFND | 61,669 | 0 | 686,520 | ||
| ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 | COM | 27923D108 | 114 | 63,092 | SH | DFND | 4,804 | 0 | 58,288 | ||
| ELBIT SYSTEMS LTD ISIN #IL0010811243 SEDOL #6308913 | COM | M3760D101 | 40,327 | 274,182 | SH | DFND | 120,364 | 0 | 153,818 | ||
| ELECTRONIC ARTS | COM | 285512109 | 29,358 | 248,670 | SH | DFND | 60,564 | 0 | 188,106 | ||
| ENPHASE ENERGY INC COM USD0.00001 | COM | 29355A107 | 2,543 | 1,672,927 | SH | DFND | 284,951 | 0 | 1,387,976 | ||
| ENZO BIOCHEM INC | COM | 294100102 | 10,271 | 981,007 | SH | DFND | 224,177 | 0 | 756,830 | ||
| EPAM SYS INC COM USD0.001 | COM | 29414B104 | 55,011 | 625,624 | SH | DFND | 35,096 | 0 | 590,528 | ||
| EROS INTERNATIONAL COM GBP0.30 | COM | G3788M114 | 59,045 | 4,128,989 | SH | DFND | 1,271,327 | 0 | 2,857,662 | ||
| ESPERION THERAPEUTICS INC COM USD0.001 | COM | 29664W105 | 85 | 1,689 | SH | DFND | 204 | 0 | 1,485 | ||
| ETSY INC COM | COM | 29786A106 | 267 | 15,806 | SH | DFND | 4,210 | 0 | 11,596 | ||
| EVERBRIDGE INC COM | COM | 29978A104 | 18,444 | 698,120 | SH | DFND | 114,644 | 0 | 583,476 | ||
| EXACT SCIENCES CORP | COM | 30063P105 | 119,659 | 2,539,452 | SH | DFND | 591,138 | 0 | 1,948,314 | ||
| EXPEDIA INC DEL COM NEW | COM | 30212P303 | 5,342 | 37,116 | SH | DFND | 1,149 | 0 | 35,967 | ||
| EXTRACTION OIL AND GAS INC COM | COM | 30227M105 | 12,396 | 805,448 | SH | DFND | 125,949 | 0 | 679,499 | ||
| FACEBOOK INC COM USD0.000006 CL A | COM | 30303M102 | 326,264 | 1,909,426 | SH | DFND | 532,012 | 0 | 1,377,414 | ||
| FAIRFAX INDIA HOLDINGS CORPORATION COM SUB VTG SHS ISIN #CA30389 | COM | 303897102 | 353 | 20,000 | SH | DFND | 20,000 | 0 | 0 | ||
| FARMER BROS CO COM | COM | 307675108 | 2,986 | 90,909 | SH | DFND | 21,645 | 0 | 69,264 | ||
| FEVERTREE DRINKS PLC ORD GBP0.0025 ISIN #GB00BRJ9BJ26 SEDOL #BRJ | COM | G33929103 | 869 | 29,603 | SH | DFND | 14,468 | 0 | 15,135 | ||
| FIRST REP BK SAN FRANCISCO CAL COM | COM | 33616C100 | 35,567 | 340,483 | SH | DFND | 45,871 | 0 | 294,612 | ||
| FLEXION THERAPEUTICS INC COM | COM | 33938J106 | 95,793 | 3,961,647 | SH | DFND | 801,161 | 0 | 3,160,486 | ||
| FLOOR &DECOR HLDGS INC CL A | COM | 339750101 | 102,965 | 2,644,866 | SH | DFND | 465,793 | 0 | 2,179,073 | ||
| FOUNDATION MEDICINE INC USD0.0001 | COM | 350465100 | 61,206 | 1,522,535 | SH | DFND | 495,343 | 0 | 1,027,192 | ||
| FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 | COM | 351858105 | 6,807 | 87,850 | SH | DFND | 2,715 | 0 | 85,135 | ||
| FRESHPET INC COM | COM | 358039105 | 26,331 | 1,682,510 | SH | DFND | 79,677 | 0 | 1,602,833 | ||
| FRONTIER DEVELOPMENTS PLC GBP0.005 ISIN #GB00BBT32N39 SEDOL #BBT | COM | ZZCCU43O0 | 1,042 | 71,396 | SH | DFND | 39,966 | 0 | 31,430 | ||
| GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 | COM | B44170106 | 28,508 | 279,777 | SH | DFND | 98,623 | 0 | 181,154 | ||
| GASLOG LTD COM USD0.01 | COM | G37585109 | 3,754 | 215,103 | SH | DFND | 52,770 | 0 | 162,333 | ||
| GEOPARK LIMITED COM USD0.001 | COM | G38327105 | 2,072 | 236,541 | SH | DFND | 77 | 0 | 236,464 | ||
| GIGAMON INC COM USD0.0001 | COM | 37518B102 | 38,619 | 916,233 | SH | DFND | 84,953 | 0 | 831,280 | ||
| GILDAN ACTIVEWEAR INC COM ISIN #CA3759161035 SEDOL #2254645 | COM | 375916103 | 9,664 | 308,939 | SH | DFND | 38,031 | 0 | 270,908 | ||
| GLAUKOS CORP COM | COM | 377322102 | 47,933 | 1,452,505 | SH | DFND | 339,791 | 0 | 1,112,714 | ||
| GLOBAL BLOOD THERAPEUTICS INC COM | COM | 37890U108 | 284 | 9,133 | SH | DFND | 3,527 | 0 | 5,606 | ||
| GOLAR LNG LIMITED COM STK USD1.00 | COM | G9456A100 | 5,056 | 223,606 | SH | DFND | 51,018 | 0 | 172,588 | ||
| GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 | COM | 380738104 | 1,632 | 1,007,385 | SH | DFND | 104,900 | 0 | 902,485 | ||
| GRACE W R & CO DEL NEW | COM | 38388F108 | 18,178 | 251,946 | SH | DFND | 50,139 | 0 | 201,807 | ||
| GRUPO FINANCIERO GALICIA SA ADR EACH REPR 10 CLASS B ARS1 LVL11 | COM | 399909100 | 22,142 | 429,611 | SH | DFND | 72,050 | 0 | 357,561 | ||
| GRUPO SUPERVIELLE S.A. SPON ADS EACH REP 5 ORD SHS CL B | COM | 40054A108 | 100 | 4,057 | SH | DFND | 770 | 0 | 3,287 | ||
| GTT COMMUNICATIONS INC COM USD0.0001 | COM | 362393100 | 59,158 | 1,869,136 | SH | DFND | 349,991 | 0 | 1,519,145 | ||
| GUIDEWIRE SOFTWARE INC COM USD0.0001 | COM | 40171V100 | 265 | 3,407 | SH | DFND | 2,486 | 0 | 921 | ||
| H &E EQUIPMENT SERVICES INC COM | COM | 404030108 | 2,583 | 88,447 | SH | DFND | 13,483 | 0 | 74,964 | ||
| HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) | COM | 40415F101 | 54,193 | 562,342 | SH | DFND | 168,150 | 0 | 394,192 | ||
| HEALTHEQUITY INC COM | COM | 42226A107 | 4,146 | 81,977 | SH | DFND | 6,665 | 0 | 75,312 | ||
| HEARTLAND EXPRESS INC COM | COM | 422347104 | 9,097 | 362,732 | SH | DFND | 60,011 | 0 | 302,721 | ||
| HERC HLDGS INC COM | COM | 42704L104 | 99 | 2,019 | SH | DFND | 1,440 | 0 | 579 | ||
| HUBSPOT INC COM | COM | 443573100 | 89,507 | 1,064,922 | SH | DFND | 114,627 | 0 | 950,295 | ||
| IDORSIA LTD ISIN #CH0363463438 SEDOL #BF0YK62 | COM | H3879B109 | 3,582 | 200,353 | SH | DFND | 37,198 | 0 | 163,155 | ||
| ILLUMINA INC COM | COM | 452327109 | 285 | 1,431 | SH | DFND | 227 | 0 | 1,204 | ||
| IMPINJ INC COM | COM | 453204109 | 91,184 | 2,191,393 | SH | DFND | 482,740 | 0 | 1,708,653 | ||
| INCYTE CORP COM | COM | 45337C102 | 61,742 | 528,882 | SH | DFND | 229,028 | 0 | 299,854 | ||
| INPHI CORPORATION COM USD0.001 | COM | 45772F107 | 4,411 | 111,140 | SH | DFND | 18,261 | 0 | 92,879 | ||
| INSULET CORP COM | COM | 45784P101 | 804 | 14,602 | SH | DFND | 6,046 | 0 | 8,556 | ||
| INTUITIVE SURGICAL INC COM NEW | COM | 46120E602 | 76,742 | 73,376 | SH | DFND | 5,335 | 0 | 68,041 | ||
| IRHYTHM TECHNOLOGIES INC COM | COM | 450056106 | 5,837 | 112,500 | SH | DFND | 13,870 | 0 | 98,630 | ||
| ITAU UNIBANCO HOLDINGS S.A. ADR EACH REPR 1 PRF NPV | COM | 465562106 | 3,410 | 248,934 | SH | DFND | 36,128 | 0 | 212,806 | ||
| JD COM INC SPONSORED ADR REPSTG COM CL A | COM | 47215P106 | 50,950 | 1,333,770 | SH | DFND | 462,610 | 0 | 871,160 | ||
| KANSAS CITY SOUTHERN COM | COM | 485170302 | 8,395 | 77,248 | SH | DFND | 7,688 | 0 | 69,560 | ||
| KITE PHARMA INC COM TENDERED FROM CUSIP 49803L109 | COM | 498TND748 | 637 | 3,545 | SH | DFND | 969 | 0 | 2,576 | ||
| KORNIT DIGITAL LTD ORD ILS0.01 | COM | M6372Q113 | 28,685 | 1,874,857 | SH | DFND | 563,992 | 0 | 1,310,865 | ||
| LENDINGCLUB CORP COM | COM | 52603A109 | 4,630 | 760,269 | SH | DFND | 130,596 | 0 | 629,673 | ||
| LGI HOMES INC COM | COM | 50187T106 | 86,821 | 1,787,544 | SH | DFND | 300,410 | 0 | 1,487,134 | ||
| LHC GROUP INC COM | COM | 50187A107 | 6,810 | 96,017 | SH | DFND | 21,433 | 0 | 74,584 | ||
| LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP | COM | 531229706 | 7,401 | 291,742 | SH | DFND | 2,153 | 0 | 289,589 | ||
| LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP | COM | 531229888 | 19,643 | 777,343 | SH | DFND | 130,776 | 0 | 646,567 | ||
| LIBERTY MEDIA CORP DELAWARE COM C SIRIUSXM | COM | 531229607 | 301 | 7,185 | SH | DFND | 183 | 0 | 7,002 | ||
| LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA | COM | 531229854 | 648 | 17,003 | SH | DFND | 452 | 0 | 16,551 | ||
| LILIS ENERGY INC COM NEW | COM | 532403201 | 5,563 | 1,244,610 | SH | DFND | 312,453 | 0 | 932,157 | ||
| LIVEPERSON INC | COM | 538146101 | 37,989 | 2,803,619 | SH | DFND | 183,025 | 0 | 2,620,594 | ||
| LUMBER LIQUIDATORS HLDGS INC COM | COM | 55003T107 | 60,690 | 1,556,963 | SH | DFND | 611,237 | 0 | 945,726 | ||
| LUMENTUM HLDGS INC COM | COM | 55024U109 | 112,227 | 2,064,892 | SH | DFND | 363,491 | 0 | 1,701,401 | ||
| MADISON SQUARE GARDEN CO NEW CL A | COM | 55825T103 | 6,388 | 29,836 | SH | DFND | 5,534 | 0 | 24,302 | ||
| MAKEMYTRIP LTD USD0.0005 | COM | V5633W109 | 3,398 | 118,192 | SH | DFND | 25,469 | 0 | 92,723 | ||
| MARTIN MARIETTA MATLS INC | COM | 573284106 | 58,902 | 285,614 | SH | DFND | 32,930 | 0 | 252,684 | ||
| MASONITE INTERNATIONAL CORP COM NPV | COM | 575385109 | 969 | 14,000 | SH | DFND | 14,000 | 0 | 0 | ||
| MASTERCARD INCORPORATED CL A | COM | 57636Q104 | 15,012 | 106,315 | SH | DFND | 21,121 | 0 | 85,194 | ||
| MATERIALISE NV SPON ADS EA REPSTG 1 ORD | COM | 57667T100 | 274 | 18,800 | SH | DFND | 2,000 | 0 | 16,800 | ||
| MAZOR ROBOTICS LTD SPON ADS EA REPR 2 ORD ILS0.00 | COM | 57886P103 | 11,782 | 238,647 | SH | DFND | 41,796 | 0 | 196,851 | ||
| MCDONALDS CORP | COM | 580135101 | 58,575 | 373,848 | SH | DFND | 25,939 | 0 | 347,909 | ||
| MEG ENERGY CORP COM ISIN #CA5527041084 SEDOL #B4XF9J1 | COM | 552704108 | 59 | 13,515 | SH | DFND | 3,600 | 0 | 9,915 | ||
| MERCADOLIBRE INC | COM | 58733R102 | 33,390 | 128,952 | SH | DFND | 44,252 | 0 | 84,700 | ||
| MERCURY SYS INC COM | COM | 589378108 | 54,073 | 1,042,267 | SH | DFND | 292,187 | 0 | 750,080 | ||
| METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 | COM | G60640102 | 163,079 | 3,596,186 | SH | DFND | 807,789 | 0 | 2,788,397 | ||
| MICRON TECHNOLOGY | COM | 595112103 | 1,571 | 39,951 | SH | DFND | 14,950 | 0 | 25,001 | ||
| MICROSOFT CORP | COM | 594918104 | 46,529 | 624,631 | SH | DFND | 148,080 | 0 | 476,551 | ||
| MIMECAST LIMITED COM USD0.012 | COM | G14838109 | 4,991 | 175,622 | SH | DFND | 8,730 | 0 | 166,892 | ||
| MONOLITHIC PWR SYS INC COM | COM | 609839105 | 11,529 | 108,204 | SH | DFND | 10,599 | 0 | 97,605 | ||
| MORRISON(WM.)SUPERMA KETS ORD GBP0.10 ISIN #GB0006043169 SEDOL # | COM | G62748119 | 303 | 96,377 | SH | DFND | 23,334 | 0 | 73,043 | ||
| MULESOFT INC CL A | COM | 625207105 | 20 | 1,017 | SH | DFND | 1,017 | 0 | 0 | ||
| NEOPHOTONICS CORP COM | COM | 64051T100 | 50 | 8,963 | SH | DFND | 1,733 | 0 | 7,230 | ||
| NETFLIX COM INC COM | COM | 64110L106 | 444,942 | 2,453,499 | SH | DFND | 573,433 | 0 | 1,880,066 | ||
| NETSHOES CAYMAN LTD COM USD0.0033 | COM | G6455X107 | 16,519 | 1,256,166 | SH | DFND | 354,613 | 0 | 901,553 | ||
| NEVRO CORP COM USD0.001 | COM | 64157F103 | 112 | 1,233 | SH | DFND | 244 | 0 | 989 | ||
| NEW HOME CO INC COM | COM | 645370107 | 350 | 31,372 | SH | DFND | 2,500 | 0 | 28,872 | ||
| NEW RELIC INC COM | COM | 64829B100 | 6,949 | 139,546 | SH | DFND | 24,732 | 0 | 114,814 | ||
| NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV | COM | 654445303 | 4,837 | 104,809 | SH | DFND | 28,064 | 0 | 76,745 | ||
| NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 | COM | J51699106 | 596 | 1,613 | SH | DFND | 415 | 0 | 1,198 | ||
| NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST | COM | 65506L105 | 65 | 1,258 | SH | DFND | 0 | 0 | 1,258 | ||
| NORTHERN DYNASTY MINS COM NPV ISIN #CA66510M2040 SEDOL #2637848 | COM | 66510M204 | 846 | 469,761 | SH | DFND | 25,612 | 0 | 444,149 | ||
| NORWEGIAN CRUISE LINE HLDGS LTD COM | COM | G66721104 | 678 | 12,535 | SH | DFND | 1,256 | 0 | 11,279 | ||
| NOVAVAX INC | COM | 670002104 | 41 | 35,817 | SH | DFND | 7,365 | 0 | 28,452 | ||
| NRG ENERGY INC COM NEW | COM | 629377508 | 226 | 8,823 | SH | DFND | 222 | 0 | 8,601 | ||
| NUTANIX INC CL A | COM | 67059N108 | 91 | 4,071 | SH | DFND | 343 | 0 | 3,728 | ||
| NUTRI SYS INC NEW COM | COM | 67069D108 | 10,275 | 183,804 | SH | DFND | 34,906 | 0 | 148,898 | ||
| NUVASIVE INC COM | COM | 670704105 | 1,257 | 22,666 | SH | DFND | 4,466 | 0 | 18,200 | ||
| NUVECTRA CORP COM | COM | 67075N108 | 13,214 | 996,557 | SH | DFND | 180,038 | 0 | 816,519 | ||
| NV5 GLOBAL INC COM | COM | 62945V109 | 9,802 | 179,364 | SH | DFND | 8,060 | 0 | 171,304 | ||
| NVIDIA CORP | COM | 67066G104 | 42,337 | 236,826 | SH | DFND | 93,161 | 0 | 143,665 | ||
| NXSTAGE MED INC COM | COM | 67072V103 | 43,506 | 1,576,299 | SH | DFND | 571,832 | 0 | 1,004,467 | ||
| OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 | COM | G6718L106 | 72,185 | 18,381,692 | SH | DFND | 3,526,192 | 0 | 14,855,500 | ||
| OCEANAGOLD CORPORATION COM ISIN #CA6752221037 SEDOL #B1Z7L21 | COM | 675222103 | 2,534 | 840,615 | SH | DFND | 6,660 | 0 | 833,955 | ||
| OKTA INC CL A | COM | 679295105 | 21,017 | 745,031 | SH | DFND | 120,207 | 0 | 624,824 | ||
| ORASURE TECHNOLOGIES INC COM | COM | 68554V108 | 3,604 | 160,191 | SH | DFND | 4,837 | 0 | 155,354 | ||
| PACIFIC BIOSCIENCES CALIFORNIA INC COM USD0.0001 | COM | 69404D108 | 121 | 23,031 | SH | DFND | 1,790 | 0 | 21,241 | ||
| PACIFIC ETHANOL INC COM PAR $.001 | COM | 69423U305 | 12 | 2,215 | SH | DFND | 646 | 0 | 1,569 | ||
| PACIRA PHARMACEUTICALS INC COM USD0.001 | COM | 695127100 | 8,152 | 217,091 | SH | DFND | 21,494 | 0 | 195,597 | ||
| PALO ALTO NETWORKS INC COM USD0.0001 | COM | 697435105 | 10 | 71 | SH | DFND | 0 | 0 | 71 | ||
| PANDORA MEDIA INC COM | COM | 698354107 | 104 | 13,525 | SH | DFND | 1,219 | 0 | 12,306 | ||
| PAYPAL HLDGS INC COM | COM | 70450Y103 | 41,419 | 646,875 | SH | DFND | 193,628 | 0 | 453,247 | ||
| PDF SOLUTIONS INC | COM | 693282105 | 23,734 | 1,532,186 | SH | DFND | 134,335 | 0 | 1,397,851 | ||
| PENSKE AUTOMOTIVE GROUP INC | COM | 70959W103 | 3,693 | 77,639 | SH | DFND | 18,709 | 0 | 58,930 | ||
| POOL CORP COM | COM | 73278L105 | 45,709 | 422,570 | SH | DFND | 67,255 | 0 | 355,315 | ||
| PROOFPOINT INC COM USD0.0001 | COM | 743424103 | 4,614 | 52,896 | SH | DFND | 3,795 | 0 | 49,101 | ||
| Q2 HLDGS INC COM | COM | 74736L109 | 46,028 | 1,105,108 | SH | DFND | 306,662 | 0 | 798,446 | ||
| RENAISSANCERE HOLDINGS LTD COM STK USD1 | COM | G7496G103 | 23 | 167 | SH | DFND | 0 | 0 | 167 | ||
| REPUBLIC FIRST BANCORP INC COM | COM | 760416107 | 16,479 | 1,781,506 | SH | DFND | 721,807 | 0 | 1,059,699 | ||
| RIGHTMOVE PLC WINTERHILL SHS ISIN #GB00B2987V85 SEDOL #B2987V8 | COM | G75657109 | 19,643 | 361,946 | SH | DFND | 51,590 | 0 | 310,356 | ||
| RINGCENTRAL INC-CLASS A | COM | 76680R206 | 135,515 | 3,245,863 | SH | DFND | 593,590 | 0 | 2,652,273 | ||
| ROKU INC COM CL A | COM | 77543R102 | 11,920 | 449,132 | SH | DFND | 26,954 | 0 | 422,178 | ||
| SAFETY INS GROUP INC | COM | 78648T100 | 432 | 5,668 | SH | DFND | 1,170 | 0 | 4,498 | ||
| SALESFORCE COM INC | COM | 79466L302 | 41,219 | 441,226 | SH | DFND | 118,548 | 0 | 322,678 | ||
| SANGAMO THERAPEUTICS INC COM | COM | 800677106 | 464 | 30,923 | SH | DFND | 8,059 | 0 | 22,864 | ||
| SAREPTA THERAPEUTICS INC COM | COM | 803607100 | 24,226 | 534,087 | SH | DFND | 43,077 | 0 | 491,010 | ||
| SCHNEIDER NATIONAL INC CL B | COM | 80689H102 | 2,248 | 88,860 | SH | DFND | 18,957 | 0 | 69,903 | ||
| SCIENTIFIC GAMES CRP CL A | COM | 80874P109 | 2,979 | 64,965 | SH | DFND | 15,345 | 0 | 49,620 | ||
| SEASPINE HLDGS CORP COM | COM | 81255T108 | 4,024 | 358,657 | SH | DFND | 64,210 | 0 | 294,447 | ||
| SECTOR SPDR TR SHS BEN INT TECHNOLOGY | COM | 81369Y803 | 1,406 | 23,789 | SH | DFND | 2,378 | 0 | 21,411 | ||
| SENESTECH INC COM | COM | 81720R109 | 1,995 | 1,078,499 | SH | DFND | 114,704 | 0 | 963,795 | ||
| SEQUANS COMMUNICATIONS SPON ADR EA REPR 1 ORD SHS | COM | 817323108 | 2,883 | 918,053 | SH | DFND | 143,778 | 0 | 774,275 | ||
| SERVICENOW INC COM USD0.001 | COM | 81762P102 | 18,912 | 160,908 | SH | DFND | 29,418 | 0 | 131,490 | ||
| SHAKE SHACK INC CL A | COM | 819047101 | 54,075 | 1,627,284 | SH | DFND | 248,869 | 0 | 1,378,415 | ||
| SHERWIN WILLIAMS CO | COM | 824348106 | 960 | 2,680 | SH | DFND | 75 | 0 | 2,605 | ||
| SHOPIFY INC COM NPV CL A ISIN #CA82509L1076 SEDOL #BX865C7 | COM | 82509L107 | 17,791 | 152,726 | SH | DFND | 29,756 | 0 | 122,970 | ||
| SHOTSPOTTER INC COM | COM | 82536T107 | 9,856 | 732,782 | SH | DFND | 173,155 | 0 | 559,627 | ||
| SIENTRA INC COM USD0.01 | COM | 82621J105 | 16,811 | 1,091,626 | SH | DFND | 162,083 | 0 | 929,543 | ||
| SIGNATURE BK NEW YORK N Y COM | COM | 82669G104 | 3,053 | 23,847 | SH | DFND | 4,050 | 0 | 19,797 | ||
| SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 | COM | 828363101 | 751 | 643,149 | SH | DFND | 104,250 | 0 | 538,899 | ||
| SIMPLY GOOD FOODS CO COM | COM | 82900L102 | 223 | 19,010 | SH | DFND | 532 | 0 | 18,478 | ||
| SIRIUS XM HLDGS INC COM | COM | 82968B103 | 99 | 17,870 | SH | DFND | 3,564 | 0 | 14,306 | ||
| SITEONE LANDSCAPE SUPPLY INC COM | COM | 82982L103 | 21,188 | 364,675 | SH | DFND | 49,177 | 0 | 315,498 | ||
| SIX FLAGS ENTMT CORP NEW COM | COM | 83001A102 | 3,230 | 53,005 | SH | DFND | 20,232 | 0 | 32,773 | ||
| SMART SAND INC COM | COM | 83191H107 | 2,703 | 398,633 | SH | DFND | 70,360 | 0 | 328,273 | ||
| SNAP INC CL A | COM | 83304A106 | 31,631 | 2,175,474 | SH | DFND | 430,751 | 0 | 1,744,723 | ||
| SOCIAL CAP HEDOSOPHIA HLDGS CORP UNIT 1 CL A & 1/3 WT EXP ISIN # | COM | G8250R111 | 2,184 | 206,994 | SH | DFND | 34,392 | 0 | 172,602 | ||
| SOLARIS OILFIELD INFRSTR INC COM CL A | COM | 83418M103 | 26,304 | 1,509,110 | SH | DFND | 189,122 | 0 | 1,319,988 | ||
| SPIRIT AIRLS INC COM | COM | 848577102 | 11,687 | 349,801 | SH | DFND | 35,651 | 0 | 314,150 | ||
| SPLUNK INC COM USD0.001 | COM | 848637104 | 3,602 | 54,230 | SH | DFND | 5,585 | 0 | 48,645 | ||
| SQUARE INC CL A | COM | 852234103 | 12,007 | 416,768 | SH | DFND | 69,798 | 0 | 346,970 | ||
| SS&C TECHNOLOGIES HLDGS INC COM | COM | 78467J100 | 29,925 | 745,326 | SH | DFND | 130,146 | 0 | 615,180 | ||
| STAMPS COM INC COM NEW | COM | 852857200 | 218 | 1,076 | SH | DFND | 224 | 0 | 852 | ||
| STEADYMED LTD ILS0.01 | COM | M84920103 | 72 | 21,496 | SH | DFND | 4,112 | 0 | 17,384 | ||
| STRAIGHT PATH COMMUNICATIONS INC COM USD0.01 CL B | COM | 862578101 | 11,346 | 62,801 | SH | DFND | 4,879 | 0 | 57,922 | ||
| SUMMIT MATLS INC CL A | COM | 86614U100 | 14,508 | 452,937 | SH | DFND | 30,433 | 0 | 422,504 | ||
| SUNOPTA INC COM ISIN #CA8676EP1086 SEDOL #2817510 | COM | 8676EP108 | 5,105 | 586,814 | SH | DFND | 91,770 | 0 | 495,044 | ||
| SUNRUN INC COM | COM | 86771W105 | 337 | 60,637 | SH | DFND | 6,332 | 0 | 54,305 | ||
| SVB FINL GROUP | COM | 78486Q101 | 5,180 | 27,688 | SH | DFND | 4,748 | 0 | 22,940 | ||
| T MOBILE US INC COM | COM | 872590104 | 315 | 5,102 | SH | DFND | 474 | 0 | 4,628 | ||
| TACTILE SYS TECHNOLOGY INC COM | COM | 87357P100 | 14,451 | 466,903 | SH | DFND | 83,356 | 0 | 383,547 | ||
| TAKE-TWO INTERACTIVE SOFTWARE COM | COM | 874054109 | 50,272 | 491,757 | SH | DFND | 147,265 | 0 | 344,492 | ||
| TAL EDUCATION GROUP SPON ADS EACH REP 0.3333 CL A ORD SHS | COM | 874080104 | 85,311 | 2,530,746 | SH | DFND | 566,439 | 0 | 1,964,307 | ||
| TALEND SA ADR EACH REP 1 ORD SHS | COM | 874224207 | 1,614 | 39,431 | SH | DFND | 7,387 | 0 | 32,044 | ||
| TELADOC INC COM | COM | 87918A105 | 37,744 | 1,138,577 | SH | DFND | 417,871 | 0 | 720,706 | ||
| TELARIA INC COM | COM | 879181105 | 1,823 | 418,141 | SH | DFND | 23,871 | 0 | 394,270 | ||
| TELESITES SAB DE CV COM NPV SER B-1 ISIN #MX01SI080038 SEDOL #BD | COM | P90355135 | 153 | 199,189 | SH | DFND | 13,077 | 0 | 186,112 | ||
| TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM | COM | G87572163 | 73,587 | 1,709,593 | SH | DFND | 504,987 | 0 | 1,204,606 | ||
| TESLA INC COM | COM | 88160R101 | 236,509 | 693,372 | SH | DFND | 243,027 | 0 | 450,345 | ||
| THERAPEUTICSMD INC COM | COM | 88338N107 | 13,070 | 2,470,766 | SH | DFND | 1,079,031 | 0 | 1,391,735 | ||
| TIME INC NEW COM | COM | 887228104 | 25 | 1,826 | SH | DFND | 0 | 0 | 1,826 | ||
| TRANSDIGM GROUP INC COM | COM | 893641100 | 4,936 | 19,309 | SH | DFND | 183 | 0 | 19,126 | ||
| TRIPADVISOR INC COM | COM | 896945201 | 366 | 9,033 | SH | DFND | 234 | 0 | 8,799 | ||
| TSO3 INC COM ISIN #CA8730151013 SEDOL #2798518 | COM | 873015101 | 11,445 | 5,463,113 | SH | DFND | 496,611 | 0 | 4,966,502 | ||
| TWITTER INC COM USD0.000005 | COM | 90184L102 | 673 | 39,903 | SH | DFND | 17,792 | 0 | 22,111 | ||
| UBIQUITI NETWORKS INC COM USD0.001 | COM | 90347A100 | 178 | 3,175 | SH | DFND | 268 | 0 | 2,907 | ||
| ULTIMATE SOFTWARE GROUP INC | COM | 90385D107 | 74 | 389 | SH | DFND | 128 | 0 | 261 | ||
| UNIVERSAL DISPLAY CORP | COM | 91347P105 | 589 | 4,568 | SH | DFND | 3,241 | 0 | 1,327 | ||
| VALIDUS HOLDING LTD COM STK USD0.175 | COM | G9319H102 | 5,180 | 105,263 | SH | DFND | 27,421 | 0 | 77,842 | ||
| VANECK VECTORS ETF TR GOLD MINERS ETF | COM | 92189F106 | 11,510 | 501,307 | SH | DFND | 17,175 | 0 | 484,132 | ||
| VEEVA SYS INC CL A COM | COM | 922475108 | 47,165 | 836,119 | SH | DFND | 285,519 | 0 | 550,600 | ||
| VIVENDI SA EUR5.50 ISIN #FR0000127771 SEDOL #4834777 | COM | F97982106 | 106,611 | 4,210,092 | SH | DFND | 753,932 | 0 | 3,456,160 | ||
| VOCERA COMMUNICATIONS INC COM | COM | 92857F107 | 7,736 | 246,603 | SH | DFND | 43,986 | 0 | 202,617 | ||
| VOYAGER THERAPEUTICS INC COM | COM | 92915B106 | 46 | 2,217 | SH | DFND | 460 | 0 | 1,757 | ||
| WAL-MART STORES INC COM | COM | 931142103 | 82,870 | 1,060,530 | SH | DFND | 191,318 | 0 | 869,212 | ||
| WARRIOR MET COAL INC COM | COM | 93627C101 | 204 | 8,674 | SH | DFND | 0 | 0 | 8,674 | ||
| WEIBO CORP SPONSORED ADR | COM | 948596101 | 3,088 | 31,212 | SH | DFND | 4,961 | 0 | 26,251 | ||
| WHEATON PRECIOUS METALS CORP COM NPV ISIN #CA9628791027 SEDOL #B | COM | 962879102 | 1,711 | 89,628 | SH | DFND | 635 | 0 | 88,993 | ||
| WORKDAY INC COM USD0.001 CL A | COM | 98138H101 | 13,094 | 124,246 | SH | DFND | 24,075 | 0 | 100,171 | ||
| XILINX INC | COM | 983919101 | 26,085 | 368,279 | SH | DFND | 26,734 | 0 | 341,545 | ||
| XTREME DRILLING CORP ISIN #CA98419V1004 SEDOL #B7J8QB6 | COM | 98419V100 | 970 | 553,888 | SH | DFND | 58,202 | 0 | 495,686 | ||
| ZAI LAB LTD-ADR | COM | 98887Q104 | 15,021 | 556,322 | SH | DFND | 276,543 | 0 | 279,779 | ||
| ZAYO GROUP HLDGS INC COM | COM | 98919V105 | 258 | 7,482 | SH | DFND | 617 | 0 | 6,865 | ||
| ZENDESK INC COM USD0.01 | COM | 98936J101 | 3,883 | 133,405 | SH | DFND | 25,811 | 0 | 107,594 | ||
| ZILLOW GROUP INC CL A | COM | 98954M101 | 17,462 | 434,919 | SH | DFND | 31,175 | 0 | 403,744 | ||
| ZILLOW GROUP INC CL C CAP STK | COM | 98954M200 | 38,469 | 956,698 | SH | DFND | 77,064 | 0 | 879,634 | ||
| ZOETIS INC COM USD0.01 CL A | COM | 98978V103 | 497 | 7,795 | SH | DFND | 237 | 0 | 7,558 | ||