The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 34,297 526,354 SH   DFND   0 526,354 0
ACCURAY INC COM 004397105 19,480 4,101,121 SH   DFND   0 4,101,121 0
AERIE PHARMACEUTICALS INC COM 00771V108 58,643 1,293,129 SH   DFND   0 1,293,129 0
AKORN INC COM 009728106 43,758 1,817,174 SH   DFND   0 1,817,174 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 21,740 1,045,181 SH   DFND   0 1,045,181 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 87,344 810,019 SH   DFND   0 810,019 0
AMERICAN TOWER CORP NEW COM 03027X100 27,533 226,537 SH   DFND   0 226,537 0
ANTHEM INC COM 036752103 72,788 440,126 SH   DFND   0 440,126 0
APPLE INC COM 037833100 36,207 252,032 SH   DFND   0 252,032 0
ARCELORMITTAL SA LUXEMBOURG NY REGISTRY SH 03938L104 4,604 551,390 SH   DFND   0 551,390 0
ARDELYX INC COM 039697107 14,036 1,109,574 SH   DFND   0 1,109,574 0
ATHENAHEALTH INC COM 04685W103 38,601 342,540 SH   DFND   0 342,540 0
AVEXIS INC COM 05366U100 5,335 70,170 SH   DFND   0 70,170 0
BAXTER INTL INC COM 071813109 60,287 1,162,488 SH   DFND   0 1,162,488 0
BIOGEN INC COM 09062X103 106,815 390,664 SH   DFND   0 390,664 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 86,299 983,126 SH   DFND   0 983,126 0
BIOMARIN PHARMACEUTICAL INC NOTE 0.750%10/1 09061GAE1 33,956 29,934,000 PRN   DFND   0 29,934,000 0
BLUEPRINT MEDICINES CORP COM 09627Y109 42,070 1,052,012 SH   DFND   0 1,052,012 0
CARDIOVASCULAR SYS INC DEL COM 141619106 12,488 441,661 SH   DFND   0 441,661 0
CIGNA CORPORATION COM 125509109 43,155 294,596 SH   DFND   0 294,596 0
CIRRUS LOGIC INC COM 172755100 11,112 183,100 SH   DFND   0 183,100 0
CLOVIS ONCOLOGY INC COM 189464100 64,082 1,006,472 SH   DFND   0 1,006,472 0
CLOVIS ONCOLOGY INC NOTE 2.500% 9/1 189464AB6 93,238 72,138,000 PRN   DFND   0 72,138,000 0
COHERUS BIOSCIENCES INC COM 19249H103 31,718 1,499,682 SH   DFND   0 1,499,682 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 7,993 794,550 SH   DFND   0 794,550 0
COMMSCOPE HLDG CO INC COM 20337X109 47,642 1,142,225 SH   DFND   0 1,142,225 0
COMPUTER SCIENCES CORP COM 205363104 98,014 1,420,281 SH   DFND   0 1,420,281 0
CORNERSTONE ONDEMAND INC COM 21925Y103 30,649 788,083 SH   DFND   0 788,083 0
EDWARDS LIFESCIENCES CORP COM 28176E108 42,968 456,766 SH   DFND   0 456,766 0
ENDOLOGIX INC COM 29266S106 14,797 2,043,786 SH   DFND   0 2,043,786 0
ENDOLOGIX INC NOTE 2.250%12/1 29266SAA4 14,054 14,583,000 PRN   DFND   0 14,583,000 0
ENDOLOGIX INC NOTE 3.250%11/0 29266SAB2 17,197 17,316,000 PRN   DFND   0 17,316,000 0
EVOLENT HEALTH INC CL A 30050B101 10,713 480,422 SH   DFND   0 480,422 0
FACEBOOK INC CL A 30303M102 47,372 333,491 SH   DFND   0 333,491 0
FLUIDIGM CORP DEL NOTE 2.750% 2/0 34385PAA6 7,994 11,670,000 PRN   DFND   0 11,670,000 0
GODADDY INC CL A 380237107 67,442 1,779,472 SH   DFND   0 1,779,472 0
HAIN CELESTIAL GROUP INC COM 405217100 36,819 989,755 SH   DFND   0 989,755 0
HERBALIFE LTD COM USD SHS G4412G101 26,341 453,062 SH   DFND   0 453,062 0
HERON THERAPEUTICS INC COM 427746102 58,991 3,932,730 SH   DFND   0 3,932,730 0
HOLOGIC INC COM 436440101 51,624 1,213,261 SH   DFND   0 1,213,261 0
HUMANA INC COM 444859102 81,393 394,842 SH   DFND   0 394,842 0
ICON PLC SHS G4705A100 22,965 288,068 SH   DFND   0 288,068 0
INOGEN INC COM 45780L104 4,805 61,951 SH   DFND   0 61,951 0
INTERSECT ENT INC COM 46071F103 2,394 139,611 SH   DFND   0 139,611 0
INVUITY INC COM NEW 46187J205 3,418 429,891 SH   DFND   0 429,891 0
ISHARES TR CALL 464287906 40,295 137,400 SH Call DFND   0 137,400 0
ISHARES TR PUT 464287956 59,065 201,400 SH Put DFND   0 201,400 0
ISHARES TR PUT 464287956 64,666 220,500 SH Put DFND   0 220,500 0
JAZZ PHARMACEUTICALS PLC CALL G50871905 27,996 192,900 SH Call DFND   0 192,900 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 125,432 864,276 SH   DFND   0 864,276 0
JOUNCE THERAPEUTICS INC COM 481116101 10,967 498,714 SH   DFND   0 498,714 0
JUNO THERAPEUTICS INC COM 48205A109 2,545 114,695 SH   DFND   0 114,695 0
KITE PHARMA INC COM 49803L109 66,355 845,393 SH   DFND   0 845,393 0
KURA ONCOLOGY INC COM 50127T109 17,892 2,033,229 SH   DFND   0 2,033,229 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 110,808 3,089,161 SH   DFND   0 3,089,161 0
LILLY ELI & CO COM 532457108 48,384 575,249 SH   DFND   0 575,249 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 129,399 8,479,622 SH   DFND   0 8,479,622 0
MEDICINES CO CALL 584688905 787 16,100 SH Call DFND   0 16,100 0
MEDICINES CO CALL 584688905 14,616 298,900 SH Call DFND   0 298,900 0
MEDICINES CO COM 584688105 90,496 1,850,635 SH   DFND   0 1,850,635 0
MEDICINES CO NOTE 2.500% 1/1 584688AE5 15,386 9,730,000 PRN   DFND   0 9,730,000 0
MICROSOFT CORP COM 594918104 21,747 330,204 SH   DFND   0 330,204 0
MOLINA HEALTHCARE INC COM 60855R100 24,360 534,221 SH   DFND   0 534,221 0
MYOKARDIA INC COM 62857M105 20,231 1,538,507 SH   DFND   0 1,538,507 0
NETEASE INC SPONSORED ADR 64110W102 35,979 126,686 SH   DFND   0 126,686 0
NEVRO CORP COM 64157F103 10,948 116,836 SH   DFND   0 116,836 0
PACIRA PHARMACEUTICALS INC COM 695127100 74,204 1,627,277 SH   DFND   0 1,627,277 0
PALO ALTO NETWORKS INC COM 697435105 44,051 390,941 SH   DFND   0 390,941 0
PATTERSON COMPANIES INC COM 703395103 28,760 635,863 SH   DFND   0 635,863 0
PAYPAL HLDGS INC COM 70450Y103 21,747 505,510 SH   DFND   0 505,510 0
PENUMBRA INC COM 70975L107 29,675 355,607 SH   DFND   0 355,607 0
PORTOLA PHARMACEUTICALS INC COM 737010108 66,329 1,692,510 SH   DFND   0 1,692,510 0
PUMA BIOTECHNOLOGY INC COM 74587V107 39,631 1,065,356 SH   DFND   0 1,065,356 0
REGENXBIO INC COM 75901B107 15,406 798,247 SH   DFND   0 798,247 0
SAGE THERAPEUTICS INC COM 78667J108 5,341 75,158 SH   DFND   0 75,158 0
SCHLUMBERGER LTD COM 806857108 42,907 549,389 SH   DFND   0 549,389 0
SCHWAB CHARLES CORP NEW COM 808513105 42,192 1,033,855 SH   DFND   0 1,033,855 0
SEAGATE TECHNOLOGY PLC SHS G7945M107 10,658 232,051 SH   DFND   0 232,051 0
SPDR SERIES TRUST PUT 78464A950 77,286 1,114,600 SH Put DFND   0 1,114,600 0
SPECTRANETICS CORP COM 84760C107 42,261 1,451,030 SH   DFND   0 1,451,030 0
SPLUNK INC COM 848637104 42,523 682,657 SH   DFND   0 682,657 0
SQUARE INC CL A 852234103 13,654 790,147 SH   DFND   0 790,147 0
STARBUCKS CORP COM 855244109 77,528 1,327,769 SH   DFND   0 1,327,769 0
TEREX CORP NEW COM 880779103 5,515 175,632 SH   DFND   0 175,632 0
TESORO CORP COM 881609101 37,359 460,878 SH   DFND   0 460,878 0
TWENTY FIRST CENTY FOX INC CL A 90130A101 53,875 1,663,321 SH   DFND   0 1,663,321 0
U S SILICA HLDGS INC COM 90346E103 64,817 1,350,636 SH   DFND   0 1,350,636 0
UNION PAC CORP COM 907818108 31,723 299,502 SH   DFND   0 299,502 0
UNITEDHEALTH GROUP INC COM 91324P102 51,400 313,398 SH   DFND   0 313,398 0
UNIVERSAL HLTH SVCS INC CL B 913903100 86,861 697,958 SH   DFND   0 697,958 0
VISA INC COM CL A 92826C839 25,418 286,015 SH   DFND   0 286,015 0
VOYAGER THERAPEUTICS INC COM 92915B106 19,804 1,495,801 SH   DFND   0 1,495,801 0
VULCAN MATLS CO COM 929160109 14,306 118,745 SH   DFND   0 118,745 0
WEATHERFORD INTL LTD NOTE 5.875% 7/0 947075AH0 93,785 72,878,000 PRN   DFND   0 72,878,000 0
WEATHERFORD INTL PLC ORD SHS G48833100 101,675 15,289,479 SH   DFND   0 15,289,479 0
WERNER ENTERPRISES INC COM 950755108 9,914 378,393 SH   DFND   0 378,393 0
ZAYO GROUP HLDGS INC COM 98919V105 18,246 554,591 SH   DFND   0 554,591 0
ZELTIQ AESTHETICS INC COM 98933Q108 115 2,062 SH   DFND   0 2,062 0
ZIONS BANCORPORATION COM 989701107 21,084 501,992 SH   DFND   0 501,992 0