The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABEONA THERAPEUTICS INC COM 00289Y107 338 67,537 SH   SOLE 67,537 0 0
ACHILLION PHARMACEUTICALS COM 00448Q201 827 196,500 SH   SOLE 196,500 0 0
ADAMIS PHARMACEUTICALS CORP COM NEW 00547W208 128 30,000 SH   SOLE 30,000 0 0
ADVAXIS INC COM NEW 007624208 1,405 172,000 SH   SOLE 172,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM ADDED 00773J103 2,610 350,392 SH   SOLE 350,392 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 2,121 46,770 SH   SOLE 46,770 0 0
AFFIMED THERAPEUTICS BV COM N01045108 213 92,500 SH   SOLE 92,500 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 648 70,455 SH   SOLE 70,455 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 4,597 221,013 SH   SOLE 221,013 0 0
ANAPTYSBIO INC COM ADDED 032724106 125 4,500 SH   SOLE 4,500 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 2,836 411,000 SH   SOLE 411,000 0 0
ARDELYX INC COM 039697107 2,805 221,738 SH   SOLE 221,738 0 0
ARQULE INC COM 04269E107 855 807,008 SH   SOLE 807,008 0 0
ASCENDIS PHARMA SPONSORED ADR 04351P101 510 18,214 SH   SOLE 18,214 0 0
ATRICURE INC COM 04963C209 9,708 506,946 SH   SOLE 506,946 0 0
AXSOME THERAPEUTICS INC COM 05464T104 217 55,700 SH   SOLE 55,700 0 0
BEIGENE LTD SPONSORED ADR 07725L102 2,974 81,231 SH   SOLE 81,231 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 247 20,000 SH   SOLE 20,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 4,545 541,128 SH   SOLE 541,128 0 0
BIOLINERX LTD SPONSORED ADR 09071M106 961 1,000,000 SH   SOLE 1,000,000 0 0
BIOPHARMX CORP COM 09072X101 58 115,000 SH   SOLE 115,000 0 0
BIOTELEMETRY INC COM 090672106 2,171 75,000 SH   SOLE 75,000 0 0
BLUEBIRD BIO INC COM 09609G100 818 9,000 SH   SOLE 9,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 3,299 82,500 SH   SOLE 82,500 0 0
CARA THERAPEUTICS INC COM 140755109 1,753 95,322 SH   SOLE 95,322 0 0
CASCADIAN THERAPEUTICS INC COM NEW 14740B606 767 185,259 SH   SOLE 185,259 0 0
CELLECTIS S A SPONSORED ADS 15117K103 1,834 76,404 SH   SOLE 76,404 0 0
CELYAD ADR 151205200 328 12,528 SH   SOLE 12,528 0 0
CIDARA THERAPEUTICS INC COM 171757107 1,626 208,458 SH   SOLE 208,458 0 0
COGENTIX MEDICAL INC COM 19243A104 636 353,482 SH   SOLE 353,482 0 0
CYMABAY THERAPEUTICS INC COM COM 23257D103 379 88,067 SH   SOLE 88,067 0 0
DERMIRA INC COM 24983L104 955 28,000 SH   SOLE 28,000 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 412 35,977 SH   SOLE 35,977 0 0
EXACTECH INC COM 30064E109 797 31,636 SH   SOLE 31,636 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 1,612 325,667 SH   SOLE 325,667 0 0
GALAPAGOS NV SPON ADR 36315X101 3,048 35,359 SH   SOLE 35,359 0 0
GALENA BIOPHARMA INC COM NEW COM NEW 363256504 28 46,145 SH   SOLE 46,145 0 0
GEMPHIRE THERAPEUTICS INC COM 36870A108 554 52,797 SH   SOLE 52,797 0 0
IMMUNOMEDICS INC COM 452907108 1,634 252,574 SH   SOLE 252,574 0 0
INOTEK PHARMACEUTICALS CORP NOTE 5.750% 8/0 45780VAB8 372 600,000 PRN   SOLE 600,000 0 0
INOTEK PHARMACEUTICALS CORP COM 45780V102 474 237,135 SH   SOLE 237,135 0 0
INSULET CORP COM 45784P101 2,736 63,484 SH   SOLE 63,484 0 0
INSULET CORP NOTE 2.000% 6/1 45784PAD3 2,537 2,250,000 PRN   SOLE 2,250,000 0 0
IRONWOOD PHARMACEUTICALS INC DBCV 2.250% 6/1 46333XAD0 714 573,000 PRN   SOLE 573,000 0 0
ISHARES TR NASDQ BIOTEC ETF 464287556 2,551 8,700 SH   SOLE 8,700 0 0
JOHNSON AND JOHNSON COM 478160104 1,171 9,400 SH   SOLE 9,400 0 0
LOXO ONCOLOGY INC COM 548862101 12,654 300,722 SH   SOLE 300,722 0 0
MACROGENICS INC COM 556099109 2,217 119,200 SH   SOLE 119,200 0 0
MASIMO CORPORATION COM 574795100 326 3,500 SH   SOLE 3,500 0 0
MINERVA NEUROSCIENCES INC COM 603380106 821 101,317 SH   SOLE 101,317 0 0
NEOS THERAPEUTICS INC COM 64052L106 686 95,273 SH   SOLE 95,273 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 2,533 58,508 SH   SOLE 58,508 0 0
NEURODERM LTD ORD SHS M74231107 994 37,438 SH   SOLE 37,438 0 0
NOVADAQ TECHNOLOGIES INC COM 66987G102 747 95,841 SH   SOLE 95,841 0 0
NXSTAGE MEDICAL INC COM 67072V103 5,798 216,119 SH   SOLE 216,119 0 0
OBSEVA SA COM ADDED H5861P103 260 25,000 SH   SOLE 25,000 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 139 53,525 SH   SOLE 53,525 0 0
PROTALIX BIOTHERAPEUTICS INC NOTE 4.500% 9/1 74365AAB7 1,963 2,500,000 PRN   SOLE 2,500,000 0 0
RADIUS HEALTH INC COM NEW 750469207 1,886 48,809 SH   SOLE 48,809 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 1,567 473,478 SH   SOLE 473,478 0 0
SCYNEXIS INC COM 811292101 1,054 381,900 SH   SOLE 381,900 0 0
SIERRA ONCOLOGY INC COM ADDED 82640U107 405 265,000 SH   SOLE 265,000 0 0
SPECTRANETICS CORP COM 84760C107 1,908 65,496 SH   SOLE 65,496 0 0
STEREOTAXIS INC COM 85916J409 782 1,372,862 SH   SOLE 1,372,862 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 3,557 867,529 SH   SOLE 867,529 0 0
SYNERON MEDICAL LTD ORD SHS M87245102 907 85,947 SH   SOLE 85,947 0 0
TANDEM DIABETES CARE INC COM 875372104 869 724,286 SH   SOLE 724,286 0 0
TONIX PHARMACEUTICALS HLDG C COM ADDED 890260409 93 20,000 SH   SOLE 20,000 0 0
UNIQURE NV SHS N90064101 1,179 203,907 SH   SOLE 203,907 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 944 71,320 SH   SOLE 71,320 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,358 339,614 SH   SOLE 339,614 0 0
ZOGENIX INC COM NEW 98978L204 649 59,778 SH   SOLE 59,778 0 0