The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED COM 003654100 31,918 254,938 SH   DFND 3 254,938 0 0
ABIOMED COM 003654100 83,245 664,895 SH   DFND 2 464,385 0 200,510
ABIOMED COM 003654100 31,579 252,225 SH   DFND 1 252,225 0 0
ABIOMED COM 003654100 62,647 500,377 SH   SOLE 0 490,604 0 9,773
Acacia Reasearch Corp ACACIA TCH COM 003881307 826 143,640 SH   DFND 1 143,640 0 0
Acacia Reasearch Corp ACACIA TCH COM 003881307 1,278 222,180 SH   SOLE 0 222,180 0 0
Activision Blizzard Inc COM 00507V109 2,209 44,300 SH   DFND 2 44,300 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 3,032 550,204 SH   DFND 1 550,204 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 2,043 370,780 SH   SOLE 0 370,780 0 0
Aduro Biotechnology COM 00739L101 1,720 160,000 SH   DFND 1 160,000 0 0
Aduro Biotechnology COM 00739L101 1,397 130,000 SH   SOLE 0 130,000 0 0
Aerovironment COM 008073108 3,134 111,810 SH   DFND 1 111,810 0 0
Aerovironment COM 008073108 4,930 175,900 SH   SOLE 0 175,900 0 0
Albemarle Corp COM 012653101 4,030 38,153 SH   DFND 1 38,153 0 0
Albemarle Corp COM 012653101 5,678 53,752 SH   SOLE 0 53,752 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 157,583 1,461,404 SH   DFND 1 1,461,404 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 3,734,151 34,629,982 SH   DFND 2 15,124,296 0 19,505,686
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 241,396 2,238,672 SH   DFND 3 2,238,672 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 1,041,212 9,656,047 SH   SOLE 0 7,856,261 0 1,799,786
Alnylam Pharmaceuticals COM 02043Q107 23,361 455,820 SH   DFND 1 455,820 0 0
Alnylam Pharmaceuticals COM 02043Q107 64,693 1,262,299 SH   DFND 2 995,605 0 266,694
Alnylam Pharmaceuticals COM 02043Q107 66,153 1,290,790 SH   SOLE 0 1,270,756 0 20,034
Alnylam Pharmaceuticals COM 02043Q107 16,687 325,602 SH   DFND 3 325,602 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 14,383 16,965 SH   DFND 1 16,965 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 11,241 13,259 SH   DFND 3 13,259 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 13,078 15,426 SH   DFND 2 11,108 0 4,318
Alphabet Inc Class A CAP STK CL A 02079K305 85,427 100,763 SH   SOLE 0 100,763 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 244,157 294,321 SH   DFND 3 294,321 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 1,293,868 1,559,704 SH   DFND 2 902,914 0 656,790
Alphabet Inc Class C CAP STK CL C 02079K107 128,532 154,940 SH   DFND 1 154,940 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 810,712 977,280 SH   SOLE 0 807,345 0 169,935
Amazon.Com COM 023135106 249,009 280,877 SH   DFND 1 280,877 0 0
Amazon.Com COM 023135106 3,702,378 4,176,211 SH   DFND 2 1,831,331 0 2,344,880
Amazon.Com COM 023135106 514,173 579,977 SH   DFND 3 579,977 0 0
Amazon.Com COM 023135106 1,910,176 2,154,642 SH   SOLE 0 1,801,679 0 352,963
Ambarella SHS G037AX101 2,057 37,600 SH   DFND 1 37,600 0 0
Ambarella SHS G037AX101 2,818 51,500 SH   SOLE 0 51,500 0 0
Ameren COM 023608102 13,013 238,380 SH   DFND 1 238,380 0 0
Ameren COM 023608102 267 4,887 SH   DFND 2 4,887 0 0
American Express COM 025816109 18,584 234,916 SH   DFND 1 234,916 0 0
American Express COM 025816109 21,592 272,933 SH   DFND 2 168,672 0 104,261
American Express COM 025816109 12,516 158,215 SH   DFND 3 158,215 0 0
American Express COM 025816109 18,689 236,235 SH   SOLE 0 236,235 0 0
American States Water COM 029899101 21,245 479,580 SH   DFND 1 479,580 0 0
American States Water COM 029899101 372 8,404 SH   DFND 2 8,404 0 0
American Water Works Co COM 030420103 9,755 125,440 SH   DFND 1 125,440 0 0
American Water Works Co COM 030420103 93 1,194 SH   DFND 2 1,194 0 0
Analog Devices COM 032654105 9,420 114,952 SH   DFND 1 114,952 0 0
Analog Devices COM 032654105 13,098 159,824 SH   SOLE 0 159,824 0 0
Anthem Inc COM 036752103 40,833 246,907 SH   DFND 1 246,907 0 0
Anthem Inc COM 036752103 436,541 2,639,624 SH   DFND 2 2,126,841 0 512,783
Anthem Inc COM 036752103 95,892 579,829 SH   DFND 3 579,829 0 0
Anthem Inc COM 036752103 253,743 1,534,305 SH   SOLE 0 1,488,339 0 45,966
Apache Corp COM 037411105 20,595 400,758 SH   DFND 1 400,758 0 0
Apache Corp COM 037411105 211,969 4,124,711 SH   DFND 2 3,321,447 0 803,264
Apache Corp COM 037411105 124,276 2,418,299 SH   SOLE 0 2,345,644 0 72,655
Apache Corp COM 037411105 47,522 924,732 SH   DFND 3 924,732 0 0
Apollo Senior Floating Rate COM 037636107 10,835 617,746 SH   DFND 1 617,746 0 0
Apple COM 037833100 6,183 43,038 SH   DFND 1 43,038 0 0
Apple COM 037833100 8,892 61,899 SH   SOLE 0 61,899 0 0
Aqua America COM 03836W103 12,428 386,550 SH   DFND 1 386,550 0 0
Aqua America COM 03836W103 185 5,768 SH   DFND 2 5,768 0 0
Atlassian Corp Plc CL A G06242104 27,658 923,465 SH   DFND 3 923,465 0 0
Atlassian Corp Plc CL A G06242104 76,986 2,570,486 SH   SOLE 0 1,381,425 0 1,189,061
Atlassian Corp Plc CL A G06242104 12,303 410,770 SH   DFND 1 410,770 0 0
Atlassian Corp Plc CL A G06242104 206,312 6,888,538 SH   DFND 2 2,972,855 0 3,915,683
Autohome Inc - ADR SP ADR RP CL A 05278C107 6,135 193,105 SH   DFND 1 193,105 0 0
Autohome Inc - ADR SP ADR RP CL A 05278C107 58,581 1,843,915 SH   DFND 2 1,478,651 0 365,264
Autohome Inc - ADR SP ADR RP CL A 05278C107 13,708 431,473 SH   DFND 3 431,473 0 0
Autohome Inc - ADR SP ADR RP CL A 05278C107 38,434 1,209,753 SH   SOLE 0 1,178,114 0 31,639
Avangrid COM 05351W103 13,420 314,000 SH   DFND 1 314,000 0 0
Avangrid COM 05351W103 273 6,379 SH   DFND 2 6,379 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 86,728 502,710 SH   DFND 1 502,710 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 3,050,632 17,682,773 SH   DFND 2 7,833,515 0 9,849,258
Baidu.com Sponsored ADR SPON ADR REP A 056752108 187,054 1,084,246 SH   DFND 3 1,084,246 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 837,678 4,855,544 SH   SOLE 0 3,914,739 0 940,805
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 15,643 1,527,670 SH   DFND 1 1,527,670 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 144,445 14,105,956 SH   DFND 2 11,534,610 0 2,571,346
Baozun Spn.Adr 1:1 SPONSORED ADR 06684L103 669 44,806 SH   DFND 1 44,806 0 0
Baozun Spn.Adr 1:1 SPONSORED ADR 06684L103 916 61,326 SH   SOLE 0 61,326 0 0
Barclays Plc NOTE 8.250%12/3 06738EAA3 3,470 3,285,000 SH   DFND 1 3,285,000 0 0
Beigene Ltd SPONSORED ADR 07725L102 165 4,515 SH   DFND 1 4,515 0 0
Beigene Ltd SPONSORED ADR 07725L102 2,429 66,350 SH   DFND 2 0 0 66,350
Bioamber COM 09072Q106 703 303,040 SH   DFND 1 303,040 0 0
Bioamber COM 09072Q106 641 276,500 SH   SOLE 0 276,500 0 0
BlackRock Floating Rate Income COM 091941104 16,434 1,150,000 SH   DFND 1 1,150,000 0 0
Blackstone/GSO Strategic Credit Fund COM SHS BEN IN 09257R101 458 28,890 SH   DFND 2 28,890 0 0
Blackstone/GSO Strategic Credit Fund COM SHS BEN IN 09257R101 1,581 99,800 SH   DFND 1 99,800 0 0
Blue Capital Reinsurance Holdings Fund (USD) COM G1190F107 12,148 629,438 SH   DFND 1 629,438 0 0
Bluebird Bio Inc COM 09609G100 35,076 385,870 SH   DFND 3 385,870 0 0
Bluebird Bio Inc COM 09609G100 249,334 2,742,946 SH   DFND 2 1,265,780 0 1,477,166
Bluebird Bio Inc COM 09609G100 11,488 126,383 SH   DFND 1 126,383 0 0
Bluebird Bio Inc COM 09609G100 177,204 1,949,434 SH   SOLE 0 1,513,620 0 435,814
Bristol Myers Squibb COM 110122108 4,957 91,149 SH   DFND 1 91,149 0 0
Bristol Myers Squibb COM 110122108 3,568 65,617 SH   DFND 2 3,031 0 62,586
Bristol Myers Squibb COM 110122108 1,141 20,976 SH   DFND 3 20,976 0 0
Brown-Forman B CL B 115637209 5,609 121,463 SH   DFND 1 121,463 0 0
Brown-Forman B CL B 115637209 10,232 221,576 SH   DFND 2 141,165 0 80,411
Brown-Forman B CL B 115637209 1,320 28,578 SH   DFND 3 28,578 0 0
Brown-Forman B CL B 115637209 2,149 46,537 SH   SOLE 0 46,537 0 0
CEVA Inc COM 157210105 879 24,754 SH   SOLE 0 24,754 0 0
CEVA Inc COM 157210105 642 18,093 SH   DFND 1 18,093 0 0
CH Robinson Worldwide COM NEW 12541W209 32,472 420,129 SH   DFND 1 420,129 0 0
CH Robinson Worldwide COM NEW 12541W209 203,542 2,633,486 SH   DFND 2 2,152,448 0 481,038
CH Robinson Worldwide COM NEW 12541W209 50,754 656,672 SH   DFND 3 656,672 0 0
CH Robinson Worldwide COM NEW 12541W209 139,001 1,798,430 SH   SOLE 0 1,755,493 0 42,937
California Water Service COM 130788102 10,092 281,500 SH   DFND 1 281,500 0 0
California Water Service COM 130788102 94 2,624 SH   DFND 2 2,624 0 0
CarMax Inc COM 143130102 59,241 1,000,349 SH   DFND 3 1,000,349 0 0
CarMax Inc COM 143130102 276,936 4,676,397 SH   DFND 2 3,761,723 0 914,674
CarMax Inc COM 143130102 32,673 551,719 SH   DFND 1 551,719 0 0
CarMax Inc COM 143130102 161,448 2,726,234 SH   SOLE 0 2,652,188 0 74,046
Castlight Health Inc CL B 14862Q100 6,551 1,794,820 SH   SOLE 0 1,794,820 0 0
Celgene COM 151020104 21,075 169,369 SH   DFND 1 169,369 0 0
Celgene COM 151020104 28,929 232,495 SH   DFND 2 155,783 0 76,712
Celgene COM 151020104 13,483 108,356 SH   DFND 3 108,356 0 0
Celgene COM 151020104 19,556 157,165 SH   SOLE 0 157,165 0 0
Cemex ADR SPON ADR NEW 151290889 23,495 2,590,397 SH   DFND 1 2,590,397 0 0
Cemex ADR SPON ADR NEW 151290889 4,767 525,527 SH   SOLE 0 525,527 0 0
Cemex ADR SPON ADR NEW 151290889 247,123 27,246,158 SH   DFND 2 12,820,251 0 14,425,907
China Biologic Products Inc COM 16938C106 7,090 70,812 SH   DFND 1 70,812 0 0
China Biologic Products Inc COM 16938C106 16,938 169,160 SH   DFND 3 169,160 0 0
China Biologic Products Inc COM 16938C106 72,951 728,567 SH   DFND 2 590,910 0 137,657
China Biologic Products Inc COM 16938C106 42,730 426,745 SH   SOLE 0 413,931 0 12,814
Chipotle Mexican Grill COM 169656105 17,946 40,280 SH   DFND 1 40,280 0 0
Chipotle Mexican Grill COM 169656105 24,106 54,108 SH   DFND 2 33,768 0 20,340
Chipotle Mexican Grill COM 169656105 13,313 29,881 SH   SOLE 0 29,881 0 0
Chipotle Mexican Grill COM 169656105 11,945 26,812 SH   DFND 3 26,812 0 0
CoStar Group COM 22160N109 8,289 39,999 SH   DFND 3 39,999 0 0
CoStar Group COM 22160N109 6,383 30,805 SH   DFND 2 1,470 0 29,335
CoStar Group COM 22160N109 12,607 60,838 SH   DFND 1 60,838 0 0
CoStar Group COM 22160N109 9,202 44,408 SH   SOLE 0 44,408 0 0
Coca Cola COM 191216100 13,460 317,164 SH   DFND 1 317,164 0 0
Coca Cola COM 191216100 18,614 438,592 SH   SOLE 0 438,592 0 0
Codexis COM 192005106 3,290 685,498 SH   DFND 1 685,498 0 0
Codexis COM 192005106 2,398 499,635 SH   SOLE 0 499,635 0 0
Colgate-Palmolive COM 194162103 42,294 577,867 SH   DFND 3 577,867 0 0
Colgate-Palmolive COM 194162103 200,309 2,736,839 SH   DFND 2 2,236,839 0 500,000
Colgate-Palmolive COM 194162103 17,629 240,868 SH   DFND 1 240,868 0 0
Colgate-Palmolive COM 194162103 107,961 1,475,080 SH   SOLE 0 1,429,139 0 45,941
Consolidated Edison COM 209115104 13,306 171,340 SH   DFND 1 171,340 0 0
Consolidated Edison COM 209115104 273 3,517 SH   DFND 2 3,517 0 0
Copa Holdings S A CL A P31076105 8,350 74,387 SH   DFND 1 74,387 0 0
Copa Holdings S A CL A P31076105 232,416 2,070,518 SH   DFND 2 1,243,352 0 827,166
Copa Holdings S A CL A P31076105 33,753 300,694 SH   SOLE 0 300,694 0 0
Credicorp COM G2519Y108 170,276 1,042,717 SH   DFND 2 690,385 0 352,332
Credicorp COM G2519Y108 28,963 177,360 SH   SOLE 0 177,360 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 75,109 1,528,155 SH   DFND 1 1,528,155 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 127,278 2,589,574 SH   DFND 3 2,589,574 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 1,802,804 36,679,633 SH   DFND 2 17,064,282 0 19,615,351
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 533,091 10,846,207 SH   SOLE 0 8,934,700 0 1,911,507
Dexcom Inc COM 252131107 23,693 279,632 SH   DFND 1 279,632 0 0
Dexcom Inc COM 252131107 324,407 3,828,718 SH   DFND 2 1,692,432 0 2,136,286
Dexcom Inc COM 252131107 47,695 562,900 SH   DFND 3 562,900 0 0
Dexcom Inc COM 252131107 130,623 1,541,639 SH   SOLE 0 895,439 0 646,200
Digimarc COM 25381B101 2,511 93,000 SH   DFND 1 93,000 0 0
Digimarc COM 25381B101 2,200 81,500 SH   SOLE 0 81,500 0 0
Dolby Laboratories 'A' COM 25659T107 5,671 108,208 SH   DFND 1 108,208 0 0
Dolby Laboratories 'A' COM 25659T107 8,255 157,500 SH   SOLE 0 157,500 0 0
Donaldson COM 257651109 11,560 253,959 SH   DFND 2 253,959 0 0
EOG Resources COM 26875P101 265,830 2,725,069 SH   DFND 2 2,218,002 0 507,067
EOG Resources COM 26875P101 29,424 301,630 SH   DFND 1 301,630 0 0
EOG Resources COM 26875P101 63,979 655,862 SH   DFND 3 655,862 0 0
EOG Resources COM 26875P101 159,970 1,639,881 SH   SOLE 0 1,594,344 0 45,537
Eaton Vance Senior Income Trust SH BEN INT 27826S103 12,780 1,885,000 SH   DFND 1 1,885,000 0 0
Ecolab COM 278865100 254 2,027 SH   DFND 1 2,027 0 0
Edison International COM 281020107 19,767 248,300 SH   DFND 1 248,300 0 0
Edison International COM 281020107 363 4,555 SH   DFND 2 4,555 0 0
Ellie Mae COM 28849P100 7,778 77,569 SH   DFND 2 3,702 0 73,867
Ellie Mae COM 28849P100 18,639 185,891 SH   DFND 1 185,891 0 0
Ellie Mae COM 28849P100 10,751 107,225 SH   DFND 3 107,225 0 0
Ellie Mae COM 28849P100 14,726 146,859 SH   SOLE 0 146,859 0 0
Embraer ADR SP ADR REP 4 COM 29082A107 11,508 521,191 SH   DFND 1 521,191 0 0
Embraer ADR SP ADR REP 4 COM 29082A107 129,417 5,861,291 SH   DFND 2 2,477,383 0 3,383,908
Embraer ADR SP ADR REP 4 COM 29082A107 2,243 101,570 SH   SOLE 0 101,570 0 0
Estee Lauder 'A' COM 518439104 9,461 111,584 SH   DFND 2 111,584 0 0
Eversource Energy COM 30040W108 13,091 222,710 SH   DFND 1 222,710 0 0
Eversource Energy COM 30040W108 270 4,591 SH   DFND 2 4,591 0 0
Exa Corp COM 300614500 2,557 201,370 SH   DFND 1 201,370 0 0
Exa Corp COM 300614500 2,772 218,260 SH   SOLE 0 218,260 0 0
Exelon Corporation COM 30161N101 13,223 367,510 SH   DFND 1 367,510 0 0
Exelon Corporation COM 30161N101 274 7,617 SH   DFND 2 7,617 0 0
Facebook Cl.A CL A 30303M102 148,908 1,048,278 SH   DFND 1 1,048,278 0 0
Facebook Cl.A CL A 30303M102 1,832,750 12,902,150 SH   DFND 2 6,470,707 0 6,431,443
Facebook Cl.A CL A 30303M102 319,178 2,246,940 SH   DFND 3 2,246,940 0 0
Facebook Cl.A CL A 30303M102 1,122,158 7,899,740 SH   SOLE 0 6,062,112 0 1,837,628
Faro Technologies COM 311642102 2,367 66,200 SH   DFND 1 66,200 0 0
Faro Technologies COM 311642102 3,857 107,880 SH   SOLE 0 107,880 0 0
Fastenal COM 311900104 11,737 227,912 SH   DFND 1 227,912 0 0
Fastenal COM 311900104 11,678 226,762 SH   DFND 2 226,762 0 0
Fastenal COM 311900104 20,229 392,800 SH   SOLE 0 392,800 0 0
Ferrari NV COM N3167Y103 15,231 204,166 SH   DFND 3 204,166 0 0
Ferrari NV COM N3167Y103 226,216 3,032,349 SH   SOLE 0 3,016,068 0 16,281
Ferrari NV COM N3167Y103 1,059,813 14,206,390 SH   DFND 2 6,931,934 0 7,274,456
Ferrari NV COM N3167Y103 7,031 94,254 SH   DFND 1 94,254 0 0
Fiat Chrysler Automobiles SHS N31738102 10,156 926,427 SH   DFND 1 926,427 0 0
Fiat Chrysler Automobiles SHS N31738102 663,684 60,539,143 SH   DFND 2 36,268,001 0 24,271,142
Fiat Chrysler Automobiles SHS N31738102 22,382 2,041,670 SH   DFND 3 2,041,670 0 0
Fiat Chrysler Automobiles SHS N31738102 56,620 5,164,653 SH   SOLE 0 4,998,225 0 166,428
Financial Engines COM 317485100 19,051 437,446 SH   DFND 1 437,446 0 0
Financial Engines COM 317485100 119,724 2,749,119 SH   DFND 2 2,246,962 0 502,157
Financial Engines COM 317485100 25,873 594,102 SH   DFND 3 594,102 0 0
Financial Engines COM 317485100 77,445 1,778,297 SH   SOLE 0 1,729,070 0 49,227
First Republic Bank COM 33616C100 193,636 2,064,129 SH   SOLE 0 2,014,503 0 49,626
First Republic Bank COM 33616C100 90,904 969,026 SH   DFND 3 969,026 0 0
First Republic Bank COM 33616C100 70,483 751,337 SH   DFND 1 751,337 0 0
First Republic Bank COM 33616C100 330,192 3,519,797 SH   DFND 2 2,739,746 0 780,051
First Trust Senior Floating Rate COM 33733U108 2,540 183,676 SH   DFND 1 183,676 0 0
Foamix Pharmaceuticals SHS M46135105 550 111,200 SH   SOLE 0 111,200 0 0
Foamix Pharmaceuticals SHS M46135105 536 108,200 SH   DFND 1 108,200 0 0
Fortive Corp COM 34959J108 2,638 43,805 SH   DFND 3 43,805 0 0
Fortive Corp COM 34959J108 8,073 134,053 SH   DFND 2 6,387 0 127,666
Fortive Corp COM 34959J108 11,859 196,924 SH   DFND 1 196,924 0 0
Foundation Medicine COM 350465100 2,412 74,800 SH   DFND 1 74,800 0 0
Foundation Medicine COM 350465100 3,225 100,000 SH   SOLE 0 100,000 0 0
Goldman Sachs Gp. COM 38141G104 2,628 11,442 SH   SOLE 0 11,442 0 0
Goldman Sachs Gp. COM 38141G104 17,157 74,687 SH   DFND 2 74,687 0 0
Goldman Sachs Gp. COM 38141G104 486 2,114 SH   DFND 1 2,114 0 0
Grubhub Inc COM 400110102 38,409 1,167,799 SH   DFND 3 1,167,799 0 0
Grubhub Inc COM 400110102 107,264 3,261,303 SH   DFND 2 2,344,091 0 917,212
Grubhub Inc COM 400110102 84,813 2,578,676 SH   SOLE 0 2,528,683 0 49,993
Grubhub Inc COM 400110102 40,626 1,235,221 SH   DFND 1 1,235,221 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101 36,992 491,788 SH   SOLE 0 491,788 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101 36,692 487,798 SH   DFND 2 427,460 0 60,338
HEICO COM 422806109 2,806 32,175 SH   DFND 1 32,175 0 0
HEICO COM 422806109 5,203 59,672 SH   DFND 3 59,672 0 0
HEICO COM 422806109 6,506 74,607 SH   SOLE 0 74,607 0 0
Harley-Davidson COM 412822108 22,107 365,412 SH   DFND 2 277,984 0 87,428
Harley-Davidson COM 412822108 11,700 193,389 SH   DFND 1 193,389 0 0
Harley-Davidson COM 412822108 7,211 119,190 SH   DFND 3 119,190 0 0
Harley-Davidson COM 412822108 16,513 272,935 SH   SOLE 0 272,935 0 0
Himax Technologies Adr SPONSORED ADR 43289P106 18,164 1,991,693 SH   DFND 2 1,315,893 0 675,800
Himax Technologies Adr SPONSORED ADR 43289P106 3,350 367,314 SH   DFND 1 367,314 0 0
Himax Technologies Adr SPONSORED ADR 43289P106 2,239 245,510 SH   SOLE 0 245,510 0 0
Howard Hughes COM 44267D107 9,746 83,122 SH   DFND 1 83,122 0 0
Howard Hughes COM 44267D107 103,669 884,172 SH   DFND 2 711,392 0 172,780
Howard Hughes COM 44267D107 23,260 198,378 SH   DFND 3 198,378 0 0
Howard Hughes COM 44267D107 62,966 537,026 SH   SOLE 0 520,398 0 16,628
Hutchison China Meditech SPONSORED ADR 44842L103 236 11,842 SH   DFND 1 11,842 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 2,914 146,050 SH   DFND 2 0 0 146,050
ICICI Bank ADR ADR 45104G104 92,203 10,721,300 SH   SOLE 0 10,721,300 0 0
ICICI Bank ADR ADR 45104G104 76,393 8,882,921 SH   DFND 2 7,544,881 0 1,338,040
IPG Photonics Corp COM 44980X109 6,851 56,760 SH   DFND 1 56,760 0 0
IPG Photonics Corp COM 44980X109 11,803 97,790 SH   SOLE 0 97,790 0 0
Illumina COM 452327109 96,710 566,750 SH   DFND 1 566,750 0 0
Illumina COM 452327109 1,942,383 11,382,927 SH   DFND 2 4,073,268 0 7,309,659
Illumina COM 452327109 945,901 5,543,253 SH   SOLE 0 4,210,456 0 1,332,797
Illumina COM 452327109 218,167 1,278,523 SH   DFND 3 1,278,523 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 63,382 4,011,523 SH   DFND 2 3,999,271 0 12,252
Infosys Ltd ADR SPONSORED ADR 456788108 934 59,126 SH   DFND 1 59,126 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 11,901 753,252 SH   SOLE 0 753,252 0 0
Interactive Brokers Group COM 45841N107 96,696 2,785,027 SH   DFND 2 2,178,718 0 606,309
Interactive Brokers Group COM 45841N107 19,862 572,062 SH   DFND 1 572,062 0 0
Interactive Brokers Group COM 45841N107 25,780 742,522 SH   DFND 3 742,522 0 0
Interactive Brokers Group COM 45841N107 56,449 1,625,823 SH   SOLE 0 1,585,237 0 40,586
Intuitive Surgical COM NEW 46120E602 35,466 46,272 SH   DFND 1 46,272 0 0
Intuitive Surgical COM NEW 46120E602 669,827 873,911 SH   DFND 2 434,580 0 439,331
Intuitive Surgical COM NEW 46120E602 107,271 139,954 SH   DFND 3 139,954 0 0
Intuitive Surgical COM NEW 46120E602 372,911 486,531 SH   SOLE 0 354,982 0 131,549
Invesco Senior Income Trust COM 46131H107 43,032 9,294,218 SH   DFND 1 9,294,218 0 0
Invesco Senior Income Trust COM 46131H107 469 101,240 SH   DFND 2 101,240 0 0
Ionis Pharmaceuticals COM 462222100 10,323 256,797 SH   DFND 1 256,797 0 0
Ionis Pharmaceuticals COM 462222100 76,392 1,900,298 SH   SOLE 0 1,063,037 0 837,261
Ionis Pharmaceuticals COM 462222100 27,988 696,217 SH   DFND 3 696,217 0 0
Ionis Pharmaceuticals COM 462222100 199,452 4,961,485 SH   DFND 2 2,150,726 0 2,810,759
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 10,539 873,156 SH   DFND 1 873,156 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 249,177 20,644,341 SH   DFND 2 9,062,565 0 11,581,776
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 24,810 2,055,504 SH   SOLE 0 2,055,504 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 50,857 1,634,760 SH   DFND 1 1,634,760 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 394,857 12,692,295 SH   DFND 2 5,269,514 0 7,422,781
JD.Com Inc - ADR SPON ADR CL A 47215P106 24,330 782,072 SH   SOLE 0 782,072 0 0
Johnson & Johnson COM 478160104 12,240 98,274 SH   DFND 1 98,274 0 0
Johnson & Johnson COM 478160104 17,771 142,680 SH   SOLE 0 142,680 0 0
Juno Therapeutics Inc COM 48205A109 14,325 645,545 SH   DFND 1 645,545 0 0
Juno Therapeutics Inc COM 48205A109 136,507 6,151,741 SH   DFND 2 2,605,808 0 3,545,933
Juno Therapeutics Inc COM 48205A109 23,021 1,037,453 SH   DFND 3 1,037,453 0 0
Juno Therapeutics Inc COM 48205A109 74,628 3,363,124 SH   SOLE 0 2,396,285 0 966,839
Kirby COM 497266106 11,499 162,997 SH   DFND 1 162,997 0 0
Kirby COM 497266106 117,515 1,665,692 SH   DFND 2 1,335,610 0 330,082
Kirby COM 497266106 25,301 358,621 SH   DFND 3 358,621 0 0
Kirby COM 497266106 68,379 969,225 SH   SOLE 0 938,433 0 30,792
Kite Pharma COM 49803L109 201 2,564 SH   DFND 1 2,564 0 0
Korea Electric Power ADR SPONSORED ADR 500631106 269 13,000 SH   DFND 2 13,000 0 0
Lendingtree COM 52603B107 8,223 65,600 SH   DFND 1 65,600 0 0
Lendingtree COM 52603B107 21,949 175,100 SH   SOLE 0 175,100 0 0
Leucadia National COM 527288104 19,141 736,201 SH   DFND 1 736,201 0 0
Leucadia National COM 527288104 196,621 7,562,332 SH   DFND 2 6,100,706 0 1,461,626
Leucadia National COM 527288104 43,716 1,681,370 SH   DFND 3 1,681,370 0 0
Leucadia National COM 527288104 115,329 4,435,748 SH   SOLE 0 4,306,006 0 129,742
Liberty Tripadvisor Holding A COM SER A 531465102 7,661 543,314 SH   SOLE 0 543,314 0 0
Lincoln Electric Hdg. COM 533900106 22,504 259,087 SH   DFND 1 259,087 0 0
Lincoln Electric Hdg. COM 533900106 233,240 2,685,239 SH   DFND 2 2,182,260 0 502,979
Lincoln Electric Hdg. COM 533900106 51,357 591,266 SH   DFND 3 591,266 0 0
Lincoln Electric Hdg. COM 533900106 132,644 1,527,106 SH   SOLE 0 1,481,537 0 45,569
Line Corp Sponsored Adr SPONSORED ADR 53567X101 27,054 703,439 SH   DFND 2 353,393 0 350,046
Luxoft Holding ORD SHS CL A G57279104 6,063 96,930 SH   DFND 2 0 0 96,930
M&T Bank COM 55261F104 16,922 109,362 SH   DFND 2 94,762 0 14,600
M&T Bank COM 55261F104 2,225 14,380 SH   DFND 1 14,380 0 0
M&T Bank COM 55261F104 4,253 27,486 SH   DFND 3 27,486 0 0
M&T Bank COM 55261F104 10,936 70,675 SH   SOLE 0 70,675 0 0
MakeMyTrip SHS V5633W109 80,600 2,329,489 SH   DFND 2 1,898,831 0 430,658
Markel Corp COM 570535104 44,292 45,388 SH   DFND 1 45,388 0 0
Markel Corp COM 570535104 274,880 281,680 SH   DFND 2 222,523 0 59,157
Markel Corp COM 570535104 71,134 72,894 SH   DFND 3 72,894 0 0
Markel Corp COM 570535104 153,302 157,094 SH   SOLE 0 152,798 0 4,296
MarketAxess Holdings COM 57060D108 176,798 942,973 SH   DFND 2 677,849 0 265,124
MarketAxess Holdings COM 57060D108 89,614 477,968 SH   DFND 1 477,968 0 0
MarketAxess Holdings COM 57060D108 64,257 342,723 SH   DFND 3 342,723 0 0
MarketAxess Holdings COM 57060D108 160,247 854,697 SH   SOLE 0 843,741 0 10,956
Martin Marietta Materials COM 573284106 47,290 216,680 SH   DFND 1 216,680 0 0
Martin Marietta Materials COM 573284106 325,432 1,491,099 SH   DFND 2 1,189,533 0 301,566
Martin Marietta Materials COM 573284106 79,440 363,985 SH   DFND 3 363,985 0 0
Martin Marietta Materials COM 573284106 194,701 892,100 SH   SOLE 0 868,518 0 23,582
Mastercard Inc-Class A CL A 57636Q104 53,586 476,450 SH   DFND 1 476,450 0 0
Mastercard Inc-Class A CL A 57636Q104 188,146 1,672,854 SH   SOLE 0 1,628,322 0 44,532
Mastercard Inc-Class A CL A 57636Q104 313,718 2,789,345 SH   DFND 2 2,186,482 0 602,863
Mastercard Inc-Class A CL A 57636Q104 81,480 724,459 SH   DFND 3 724,459 0 0
McDonald's COM 580135101 7,311 56,408 SH   DFND 1 56,408 0 0
McDonald's COM 580135101 10,923 84,276 SH   SOLE 0 84,276 0 0
MercadoLibre COM 58733R102 32,641 154,351 SH   DFND 1 154,351 0 0
MercadoLibre COM 58733R102 102,163 483,108 SH   SOLE 0 483,108 0 0
MercadoLibre COM 58733R102 1,181,234 5,585,825 SH   DFND 2 2,592,316 0 2,993,509
Mettler-Toledo COM 592688105 15,409 32,175 SH   DFND 1 32,175 0 0
Mettler-Toledo COM 592688105 248,702 519,309 SH   DFND 2 389,609 0 129,700
Mettler-Toledo COM 592688105 18,336 38,287 SH   DFND 3 38,287 0 0
Mettler-Toledo COM 592688105 23,870 49,842 SH   SOLE 0 49,842 0 0
Microchip Technology COM 595017104 6,099 82,660 SH   DFND 2 82,660 0 0
Microsoft COM 594918104 7,557 114,743 SH   DFND 1 114,743 0 0
Microsoft COM 594918104 10,912 165,682 SH   SOLE 0 165,682 0 0
Mindbody Cl A COM CL A 60255W105 1,928 70,233 SH   DFND 1 70,233 0 0
Mindbody Cl A COM CL A 60255W105 2,609 95,028 SH   SOLE 0 95,028 0 0
Mobileye Nv ORD SHS N51488117 391,847 6,381,865 SH   DFND 2 2,481,969 0 3,899,896
Monsanto Co COM 61166W101 15,486 136,800 SH   DFND 1 136,800 0 0
Monsanto Co COM 61166W101 98,196 867,454 SH   SOLE 0 842,366 0 25,088
Monsanto Co COM 61166W101 36,734 324,503 SH   DFND 3 324,503 0 0
Monsanto Co COM 61166W101 165,718 1,463,941 SH   DFND 2 1,180,405 0 283,536
Moody's Corp COM 615369105 37,796 337,345 SH   DFND 1 337,345 0 0
Moody's Corp COM 615369105 413,346 3,689,275 SH   DFND 2 2,995,981 0 693,294
Moody's Corp COM 615369105 90,983 812,059 SH   DFND 3 812,059 0 0
Moody's Corp COM 615369105 231,582 2,066,959 SH   SOLE 0 2,004,088 0 62,871
Myriad Genetics Inc COM 62855J104 100,952 5,257,934 SH   DFND 2 4,232,113 0 1,025,821
Myriad Genetics Inc COM 62855J104 23,487 1,223,281 SH   DFND 3 1,223,281 0 0
Myriad Genetics Inc COM 62855J104 9,242 481,329 SH   DFND 1 481,329 0 0
Myriad Genetics Inc COM 62855J104 56,830 2,959,909 SH   SOLE 0 2,868,267 0 91,642
NVIDIA COM 67066G104 150,667 1,383,150 SH   DFND 3 1,383,150 0 0
NVIDIA COM 67066G104 850,899 7,811,430 SH   DFND 2 4,451,507 0 3,359,923
NVIDIA COM 67066G104 64,813 595,001 SH   DFND 1 595,001 0 0
NVIDIA COM 67066G104 445,783 4,092,382 SH   SOLE 0 3,192,218 0 900,164
National Instruments Corp COM 636518102 9,334 286,660 SH   DFND 1 286,660 0 0
National Instruments Corp COM 636518102 12,782 392,561 SH   SOLE 0 392,561 0 0
Netease.com ADR SPONSORED ADR 64110W102 527 1,856 SH   DFND 1 1,856 0 0
Netflix Inc COM 64110L106 104,196 704,930 SH   DFND 3 704,930 0 0
Netflix Inc COM 64110L106 590,590 3,995,601 SH   DFND 2 1,821,868 0 2,173,733
Netflix Inc COM 64110L106 60,322 408,105 SH   DFND 1 408,105 0 0
Netflix Inc COM 64110L106 367,228 2,484,461 SH   SOLE 0 1,851,161 0 633,300
New Oriental Education & Technology Sponsored ADR SPON ADR 647581107 496,191 8,217,804 SH   DFND 2 3,289,255 0 4,928,549
Novadaq Technologies Inc COM 66987G102 2,308 296,270 SH   DFND 1 296,270 0 0
Novadaq Technologies Inc COM 66987G102 3,180 408,210 SH   SOLE 0 408,210 0 0
Now Inc/DE COM 67011P100 21,043 1,240,721 SH   DFND 1 1,240,721 0 0
Now Inc/DE COM 67011P100 104,025 6,133,561 SH   DFND 2 4,757,973 0 1,375,588
Now Inc/DE COM 67011P100 63,139 3,722,828 SH   SOLE 0 3,625,332 0 97,496
Now Inc/DE COM 67011P100 29,273 1,726,030 SH   DFND 3 1,726,030 0 0
Nuveen Credit Strategies Income Fund COM SHS 67073D102 450 51,800 SH   DFND 2 51,800 0 0
Nuveen Credit Strategies Income Fund COM SHS 67073D102 1,556 179,100 SH   DFND 1 179,100 0 0
Nuveen Senior Income Fund COM 67067Y104 13,003 1,915,000 SH   DFND 1 1,915,000 0 0
PG&E Corp COM 69331C108 359 5,408 SH   DFND 2 5,408 0 0
PG&E Corp COM 69331C108 19,446 293,040 SH   DFND 1 293,040 0 0
Paccar COM 693718108 10,658 158,600 SH   DFND 2 158,600 0 0
Paccar COM 693718108 495 7,363 SH   DFND 1 7,363 0 0
Paccar COM 693718108 2,552 37,972 SH   SOLE 0 37,972 0 0
Pacira Pharmaceuticals COM 695127100 5,180 113,600 SH   DFND 1 113,600 0 0
Pacira Pharmaceuticals COM 695127100 4,560 100,000 SH   SOLE 0 100,000 0 0
Pepsico COM 713448108 9,240 82,605 SH   DFND 1 82,605 0 0
Pepsico COM 713448108 13,355 119,389 SH   SOLE 0 119,389 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 14,436 1,489,810 SH   DFND 1 1,489,810 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 141,272 14,579,130 SH   DFND 2 12,090,920 0 2,488,210
Philip Morris Intl COM 718172109 6,514 57,700 SH   DFND 1 57,700 0 0
Philip Morris Intl COM 718172109 4,426 39,202 SH   SOLE 0 39,202 0 0
Pioneer Floating Rate Trust COM 72369J102 15,114 1,236,803 SH   DFND 1 1,236,803 0 0
Praxair COM 74005P104 8,328 70,221 SH   DFND 2 70,221 0 0
PriceSmart COM 741511109 101,363 1,099,381 SH   DFND 2 861,662 0 237,719
PriceSmart COM 741511109 21,110 228,959 SH   SOLE 0 228,959 0 0
Procter & Gamble COM 742718109 11,822 131,576 SH   DFND 1 131,576 0 0
Procter & Gamble COM 742718109 16,542 184,109 SH   SOLE 0 184,109 0 0
Qiagen N.V SHS NEW N72482123 11,078 382,399 SH   DFND 1 382,399 0 0
Qiagen N.V SHS NEW N72482123 63,123 2,178,912 SH   SOLE 0 2,109,333 0 69,579
Qiagen N.V SHS NEW N72482123 25,263 872,049 SH   DFND 3 872,049 0 0
Qiagen N.V SHS NEW N72482123 110,007 3,797,260 SH   DFND 2 3,054,232 0 743,028
Regeneron Pharmaceuticals COM 75886F107 2,131 5,500 SH   DFND 2 5,500 0 0
Resmed Inc COM 761152107 185,716 2,580,461 SH   DFND 2 2,080,721 0 499,740
Resmed Inc COM 761152107 42,566 591,442 SH   DFND 3 591,442 0 0
Resmed Inc COM 761152107 17,696 245,876 SH   DFND 1 245,876 0 0
Resmed Inc COM 761152107 109,488 1,521,295 SH   SOLE 0 1,476,341 0 44,954
Restaurant Brands International COM 76131D103 169,342 3,048,634 SH   DFND 2 2,023,510 0 1,025,124
Restaurant Brands International COM 76131D103 28,175 507,235 SH   SOLE 0 507,235 0 0
Reynolds American COM 761713106 11,523 182,846 SH   DFND 1 182,846 0 0
Reynolds American COM 761713106 12,716 201,784 SH   SOLE 0 201,784 0 0
Rio Tinto Spn.Adr 1:1 SPONSORED ADR 767204100 2,873 70,626 SH   DFND 2 70,626 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 12,551 381,486 SH   DFND 1 381,486 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 73,788 2,242,794 SH   SOLE 0 2,174,902 0 67,892
Ritchie Bros Auctioneers (USA) COM 767744105 30,130 915,817 SH   DFND 3 915,817 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 194,712 5,918,289 SH   DFND 2 4,819,571 0 1,098,718
Ritchie Bros. Auctioneers COM 767744105 54,197 1,651,350 SH   DFND 2 785,050 0 866,300
Ritchie Bros. Auctioneers COM 767744105 19,779 602,645 SH   SOLE 0 602,645 0 0
Royal Crbn.Cruises COM V7780T103 64,466 657,077 SH   DFND 1 657,077 0 0
Royal Crbn.Cruises COM V7780T103 692,726 7,060,703 SH   DFND 2 5,698,705 0 1,361,998
Royal Crbn.Cruises COM V7780T103 402,791 4,105,500 SH   SOLE 0 3,983,252 0 122,248
Royal Crbn.Cruises COM V7780T103 152,364 1,552,988 SH   DFND 3 1,552,988 0 0
Ryanair ADR SPONSORED ADR NE 783513203 575,776 6,938,731 SH   DFND 2 4,987,877 0 1,950,854
Ryanair ADR SPONSORED ADR NE 783513203 4,201 50,626 SH   SOLE 0 50,626 0 0
SINA Corp ORD G81477104 4,136 57,350 SH   DFND 1 57,350 0 0
SINA Corp ORD G81477104 35,299 489,443 SH   DFND 2 258,906 0 230,537
SK Telecom ADR (US) SPONSORED ADR 78440P108 1,467 58,253 SH   SOLE 0 58,253 0 0
Salesforce.com COM 79466L302 16,565 200,814 SH   DFND 1 200,814 0 0
Salesforce.com COM 79466L302 345,761 4,191,556 SH   DFND 2 1,851,757 0 2,339,799
Salesforce.com COM 79466L302 50,178 608,288 SH   DFND 3 608,288 0 0
Salesforce.com COM 79466L302 164,063 1,988,888 SH   SOLE 0 1,277,649 0 711,239
Schlumberger COM 806857108 9,304 119,127 SH   DFND 2 119,127 0 0
Seattle Genetics COM 812578102 48,411 770,141 SH   DFND 1 770,141 0 0
Seattle Genetics COM 812578102 583,995 9,290,414 SH   DFND 2 5,383,428 0 3,906,986
Seattle Genetics COM 812578102 104,930 1,669,259 SH   DFND 3 1,669,259 0 0
Seattle Genetics COM 812578102 280,779 4,466,739 SH   SOLE 0 3,468,371 0 998,368
Sherwin-Williams Co COM 824348106 748 2,412 SH   DFND 1 2,412 0 0
Sherwin-Williams Co COM 824348106 6,971 22,472 SH   DFND 2 22,472 0 0
Sherwin-Williams Co COM 824348106 3,979 12,827 SH   SOLE 0 12,827 0 0
Sohu.com COM 83408W103 3,660 93,055 SH   DFND 1 93,055 0 0
Sohu.com COM 83408W103 28,898 734,761 SH   DFND 2 387,652 0 347,109
Splunk Inc COM 848637104 16,707 268,208 SH   DFND 1 268,208 0 0
Splunk Inc COM 848637104 257,821 4,139,043 SH   DFND 2 1,833,136 0 2,305,907
Splunk Inc COM 848637104 36,366 583,824 SH   DFND 3 583,824 0 0
Splunk Inc COM 848637104 100,902 1,619,880 SH   SOLE 0 936,334 0 683,546
Staar Surgical COM PAR $0.01 852312305 1,700 173,490 SH   DFND 1 173,490 0 0
Staar Surgical COM PAR $0.01 852312305 3,097 316,050 SH   SOLE 0 316,050 0 0
Stamps.Com COM NEW 852857200 2,161 18,260 SH   DFND 1 18,260 0 0
Stamps.Com COM NEW 852857200 5,005 42,290 SH   SOLE 0 42,290 0 0
Stericycle Inc COM 858912108 11,034 133,120 SH   DFND 1 133,120 0 0
Stericycle Inc COM 858912108 124,063 1,496,713 SH   DFND 2 1,222,152 0 274,561
Stericycle Inc COM 858912108 25,595 308,784 SH   DFND 3 308,784 0 0
Stericycle Inc COM 858912108 66,261 799,383 SH   SOLE 0 774,514 0 24,869
Stratasys SHS M85548101 2,352 114,800 SH   DFND 1 114,800 0 0
Stratasys SHS M85548101 2,348 114,600 SH   SOLE 0 114,600 0 0
TD Ameritrade Holding Corp COM 87236Y108 52,619 1,354,069 SH   DFND 1 1,354,069 0 0
TD Ameritrade Holding Corp COM 87236Y108 386,644 9,949,671 SH   DFND 2 7,964,324 0 1,985,347
TD Ameritrade Holding Corp COM 87236Y108 91,532 2,355,418 SH   DFND 3 2,355,418 0 0
TD Ameritrade Holding Corp COM 87236Y108 233,117 5,998,887 SH   SOLE 0 5,839,967 0 158,920
TJX Companies COM 872540109 6,722 85,004 SH   DFND 1 85,004 0 0
TJX Companies COM 872540109 13,837 174,974 SH   DFND 2 174,974 0 0
TJX Companies COM 872540109 6,516 82,392 SH   SOLE 0 82,392 0 0
TSMC ADR SPONSORED ADR 874039100 66,549 2,026,457 SH   DFND 1 2,026,457 0 0
TSMC ADR SPONSORED ADR 874039100 1,029,043 31,335,053 SH   DFND 2 22,597,910 0 8,737,143
TSMC ADR SPONSORED ADR 874039100 324,574 9,883,488 SH   SOLE 0 9,582,558 0 300,930
TSMC ADR SPONSORED ADR 874039100 126,409 3,849,243 SH   DFND 3 3,849,243 0 0
Tableau Software Class A CL A 87336U105 13,438 271,205 SH   DFND 1 271,205 0 0
Tableau Software Class A CL A 87336U105 6,469 130,546 SH   DFND 2 6,230 0 124,316
Tableau Software Class A CL A 87336U105 8,317 167,854 SH   DFND 3 167,854 0 0
Tableau Software Class A CL A 87336U105 40,912 825,679 SH   SOLE 0 825,679 0 0
Tal Education Group ADR ADS REPSTG COM 874080104 396,075 3,716,570 SH   DFND 2 1,156,489 0 2,560,081
Teladoc COM 87918A105 2,150 86,000 SH   DFND 1 86,000 0 0
Teladoc COM 87918A105 2,925 117,000 SH   SOLE 0 117,000 0 0
Teradyne COM 880770102 27,558 886,113 SH   DFND 1 886,113 0 0
Teradyne COM 880770102 154,263 4,960,226 SH   SOLE 0 4,814,359 0 145,867
Teradyne COM 880770102 59,745 1,921,057 SH   DFND 3 1,921,057 0 0
Teradyne COM 880770102 261,444 8,406,550 SH   DFND 2 6,790,189 0 1,616,361
TerraForm Power CL A COM 88104R100 19,878 1,606,970 SH   DFND 1 1,606,970 0 0
TerraForm Power CL A COM 88104R100 464 37,513 SH   DFND 2 37,513 0 0
Tesla Inc COM 88160R101 142,464 511,909 SH   DFND 1 511,909 0 0
Tesla Inc COM 88160R101 2,186,574 7,856,897 SH   DFND 2 3,139,456 0 4,717,441
Tesla Inc COM 88160R101 292,260 1,050,162 SH   DFND 3 1,050,162 0 0
Tesla Inc COM 88160R101 1,170,727 4,206,710 SH   SOLE 0 3,343,616 0 863,094
Tiffany & Co COM 886547108 766 8,038 SH   DFND 1 8,038 0 0
Tiffany & Co COM 886547108 16,114 169,086 SH   DFND 2 169,086 0 0
Tiffany & Co COM 886547108 4,022 42,205 SH   SOLE 0 42,205 0 0
TripAdvisor COM 896945201 28,389 657,754 SH   DFND 1 657,754 0 0
TripAdvisor COM 896945201 250,325 5,799,939 SH   DFND 2 3,253,024 0 2,546,915
TripAdvisor COM 896945201 109,415 2,535,107 SH   SOLE 0 1,886,798 0 648,309
TripAdvisor COM 896945201 47,777 1,106,978 SH   DFND 3 1,106,978 0 0
Trupanion COM 898202106 1,991 140,000 SH   DFND 1 140,000 0 0
Trupanion COM 898202106 10,452 735,000 SH   SOLE 0 735,000 0 0
Under Armour Inc Class A CL A 904311107 13,975 706,506 SH   DFND 1 706,506 0 0
Under Armour Inc Class A CL A 904311107 215,144 10,876,867 SH   DFND 2 4,813,127 0 6,063,740
Under Armour Inc Class A CL A 904311107 31,105 1,572,561 SH   DFND 3 1,572,561 0 0
Under Armour Inc Class A CL A 904311107 92,271 4,664,857 SH   SOLE 0 2,801,261 0 1,863,596
Under Armour Inc Class C CL C 904311206 12,846 701,987 SH   DFND 1 701,987 0 0
Under Armour Inc Class C CL C 904311206 11,251 614,826 SH   SOLE 0 614,826 0 0
Under Armour Inc Class C CL C 904311206 16,443 898,541 SH   DFND 2 568,453 0 330,088
Under Armour Inc Class C CL C 904311206 8,308 454,015 SH   DFND 3 454,015 0 0
United Parcel Service CL B 911312106 9,416 87,756 SH   DFND 1 87,756 0 0
United Parcel Service CL B 911312106 13,269 123,660 SH   SOLE 0 123,660 0 0
Varian Medical Systems Inc COM 92220P105 9,174 100,667 SH   DFND 2 100,667 0 0
Veeco Instruments COM 922417100 2,388 80,000 SH   DFND 1 80,000 0 0
Veeco Instruments COM 922417100 13,213 442,644 SH   SOLE 0 442,644 0 0
Verisk Analytics COM 92345Y106 30,587 376,971 SH   DFND 1 376,971 0 0
Verisk Analytics COM 92345Y106 198,667 2,448,451 SH   DFND 2 1,938,137 0 510,314
Verisk Analytics COM 92345Y106 50,229 619,036 SH   DFND 3 619,036 0 0
Verisk Analytics COM 92345Y106 116,731 1,438,637 SH   SOLE 0 1,399,718 0 38,919
Vertex Pharmaceuticals COM 92532F100 13,896 127,075 SH   DFND 1 127,075 0 0
Vertex Pharmaceuticals COM 92532F100 16,053 146,801 SH   DFND 2 84,991 0 61,810
Vertex Pharmaceuticals COM 92532F100 10,310 94,284 SH   SOLE 0 94,284 0 0
Vertex Pharmaceuticals COM 92532F100 9,399 85,954 SH   DFND 3 85,954 0 0
Visa Inc-Class A Shares COM CL A 92826C839 27,723 311,949 SH   DFND 1 311,949 0 0
Visa Inc-Class A Shares COM CL A 92826C839 301,073 3,387,793 SH   DFND 2 2,728,326 0 659,467
Visa Inc-Class A Shares COM CL A 92826C839 65,936 741,938 SH   DFND 3 741,938 0 0
Visa Inc-Class A Shares COM CL A 92826C839 172,882 1,945,333 SH   SOLE 0 1,886,371 0 58,962
Voya Prime Rate Trust SH BEN INT 92913A100 41,013 7,580,976 SH   DFND 1 7,580,976 0 0
Voya Prime Rate Trust SH BEN INT 92913A100 449 83,030 SH   DFND 2 83,030 0 0
WEC Energy Group COM 92939U106 11,089 182,890 SH   DFND 1 182,890 0 0
WEC Energy Group COM 92939U106 274 4,514 SH   DFND 2 4,514 0 0
Wabtec COM 929740108 175,491 2,249,889 SH   DFND 2 1,736,834 0 513,055
Wabtec COM 929740108 32,397 415,341 SH   DFND 1 415,341 0 0
Wabtec COM 929740108 47,211 605,269 SH   DFND 3 605,269 0 0
Wabtec COM 929740108 107,253 1,375,040 SH   SOLE 0 1,337,859 0 37,181
Waters COM 941848103 38,500 246,303 SH   DFND 1 246,303 0 0
Waters COM 941848103 235,946 1,509,475 SH   DFND 2 1,197,569 0 311,906
Waters COM 941848103 58,320 373,104 SH   DFND 3 373,104 0 0
Waters COM 941848103 135,717 868,255 SH   SOLE 0 845,406 0 22,849
Watsco Inc COM 942622200 30,181 210,794 SH   DFND 2 118,000 0 92,794
Watsco Inc COM 942622200 27,148 189,607 SH   DFND 1 189,607 0 0
Watsco Inc COM 942622200 18,251 127,467 SH   DFND 3 127,467 0 0
Watsco Inc COM 942622200 23,455 163,812 SH   SOLE 0 163,812 0 0
Wayfair Inc Class A CL A 94419L101 26,211 647,347 SH   DFND 1 647,347 0 0
Wayfair Inc Class A CL A 94419L101 10,172 251,218 SH   DFND 2 12,029 0 239,189
Wayfair Inc Class A CL A 94419L101 13,388 330,644 SH   DFND 3 330,644 0 0
Wayfair Inc Class A CL A 94419L101 23,606 583,005 SH   SOLE 0 583,005 0 0
Weibo Corp SPON ADR SPONSORED ADR 948596101 325 6,220 SH   DFND 1 6,220 0 0
Weibo Corp SPON ADR SPONSORED ADR 948596101 2,788 53,433 SH   DFND 2 27,114 0 26,319
Wipro Ltd ADR SPON ADR 1 SH 97651M109 3,572 349,165 SH   DFND 2 335,450 0 13,715
Wix Com SHS M98068105 96,497 1,421,160 SH   DFND 2 939,054 0 482,106
Workday Inc CL A 98138H101 19,127 229,675 SH   DFND 1 229,675 0 0
Workday Inc CL A 98138H101 366,481 4,400,585 SH   DFND 2 1,945,467 0 2,455,118
Workday Inc CL A 98138H101 53,278 639,751 SH   DFND 3 639,751 0 0
Workday Inc CL A 98138H101 216,781 2,603,040 SH   SOLE 0 1,857,318 0 745,722
Xylem COM 98419M100 274 5,457 SH   DFND 1 5,457 0 0
Yandex SHS CLASS A N97284108 16,540 754,240 SH   DFND 1 754,240 0 0
Yandex SHS CLASS A N97284108 122,467 5,584,457 SH   SOLE 0 5,449,292 0 135,165
Yandex SHS CLASS A N97284108 39,321 1,793,002 SH   DFND 3 1,793,002 0 0
Yandex SHS CLASS A N97284108 310,904 14,177,087 SH   DFND 2 10,532,363 0 3,644,724
Zillow Group Inc Class A CL A 98954M101 2,302 68,083 SH   DFND 1 68,083 0 0
Zillow Group Inc Class A CL A 98954M101 24,643 728,854 SH   DFND 2 590,239 0 138,615
Zillow Group Inc Class A CL A 98954M101 6,275 185,582 SH   DFND 3 185,582 0 0
Zillow Group Inc Class A CL A 98954M101 18,744 554,394 SH   SOLE 0 541,575 0 12,819
Zillow Group Inc Class C CL C CAP STK 98954M200 12,520 371,859 SH   DFND 1 371,859 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 61,206 1,817,826 SH   DFND 2 1,471,563 0 346,263
Zillow Group Inc Class C CL C CAP STK 98954M200 12,497 371,164 SH   DFND 3 371,164 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 41,030 1,218,598 SH   SOLE 0 1,184,728 0 33,870
iRobot COM 462726100 33,569 507,545 SH   SOLE 0 507,545 0 0
iRobot COM 462726100 10,192 154,102 SH   DFND 1 154,102 0 0