The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS COM 00448Q201 2,419 197,500 SH   SOLE 197,500 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 3,866 132,442 SH   SOLE 132,442 0 0
AFFIMED THERAPEUTICS BV COM ADDED N01045108 744 120,000 SH   SOLE 120,000 0 0
ATRICURE INC COM 04963C209 13,200 661,331 SH   SOLE 661,331 0 0
AUSPEX PHARMACEUTICALS INC COM 05211J102 7,131 135,885 SH   SOLE 135,885 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 2,027 166,656 SH   SOLE 166,656 0 0
BIOLIFE SOLUTIONS INC COM NEW 09062W204 191 116,279 SH   SOLE 116,279 0 0
BIOSPECIFICS TECHNOLOGIES COM 090931106 1,292 33,466 SH   SOLE 33,466 0 0
BIOTELEMETRY INC COM 090672106 2,364 235,645 SH   SOLE 235,645 0 0
BLUEBIRD BIO INC COM 09609G100 1,147 12,500 SH   SOLE 12,500 0 0
CARDICA INC COM 14141R101 1,040 1,486,004 SH   SOLE 1,486,004 0 0
CAREDX INC COM ADDED 14167L103 633 87,300 SH   SOLE 87,300 0 0
CELSUS THERAPEUTICS PLC SPONSORED ADR NE 15119A202 211 43,900 SH   SOLE 43,900 0 0
CHEMBIO DIAGNOSTICS INC COM NEW 163572209 103 26,287 SH   SOLE 26,287 0 0
CLOVIS ONCOLOGY INC COM 189464100 1,338 23,900 SH   SOLE 23,900 0 0
CTI BIOPHARMA CORP COM 12648L106 3,363 1,425,000 SH   SOLE 1,425,000 0 0
CUTERA INC COM 232109108 947 88,694 SH   SOLE 88,694 0 0
CYNAPSUS THERAPEUTICS INC COM 23257Y701 1,044 949,000 SH   SOLE 949,000 0 0
CYNAPSUS THERAPEUTICS INC COM 23257Y156 240 280,769 SH   SOLE 280,769 0 0
CYTRX CORP COM PAR $.001 232828509 949 346,400 SH   SOLE 346,400 0 0
DERMA SCIENCES INC COM PAR $.01 249827502 3,582 384,794 SH   SOLE 384,794 0 0
DISCOVERY LABORATORIES INC COM NEW 254668403 6,611 5,698,739 SH   SOLE 5,698,739 0 0
ENCISION INC COM 29254Q104 882 1,062,500 SH   SOLE 1,062,500 0 0
ESSA PHARMA INC PFD 296991474 222 250,000 SH   SOLE 250,000 0 0
EXACTECH INC COM 30064E109 746 31,636 SH   SOLE 31,636 0 0
FATE THERAPEUTICS INC COM 31189P102 297 59,110 SH   SOLE 59,110 0 0
GALMED PHARMACEUTICALS LTD SHS M47238106 917 158,121 SH   SOLE 158,121 0 0
GENVEC INC COM NEW 37246C307 416 200,000 SH   SOLE 200,000 0 0
GLOBEIMMUNE INC COM ADDED 37957B100 83 10,945 SH   SOLE 10,945 0 0
INSPIREMD INC COM NEW 45779A309 50 63,700 SH   SOLE 63,700 0 0
INSULET CORP COM 45784P101 5,040 109,418 SH   SOLE 109,418 0 0
INSULET CORP NOTE 2.000% 6/1 45784PAD3 2,861 2,407,000 PRN   SOLE 2,407,000 0 0
INTELLIPHARMACEUTICS INTERNA COM 458173101 631 279,260 SH   SOLE 279,260 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 3,416 21,900 SH   SOLE 21,900 0 0
JOHNSON AND JOHNSON COM 478160104 983 9,400 SH   SOLE 9,400 0 0
LPATH INC COM NEW 548910306 344 121,884 SH   SOLE 121,884 0 0
LUMENIS LTD SHS CL B M6778Q121 290 31,072 SH   SOLE 31,072 0 0
MASIMO CORPORATION COM 574795100 1,778 67,500 SH   SOLE 67,500 0 0
NANOSPHERE INC COM 63009F105 235 600,000 SH   SOLE 600,000 0 0
NEOTHETICS INC COM 64066G101 1,395 186,495 SH   SOLE 186,495 0 0
NOVADAQ TECHNOLOGIES INC COM 66987G102 4,380 263,541 SH   SOLE 263,541 0 0
NUVASIVE INC NOTE 2.750% 7/0 670704AC9 1,289 1,000,000 PRN   SOLE 1,000,000 0 0
NXSTAGE MEDICAL INC COM 67072V103 6,888 384,154 SH   SOLE 384,154 0 0
OCERA THERAPEUTICS INC COM 67552A108 4,044 634,893 SH   SOLE 634,893 0 0
PHARMACYCLICS INC COM 716933106 13,562 110,928 SH   SOLE 110,928 0 0
PROBIODRUG AG COM BRK8XK3 244 10,500 SH   SOLE 10,500 0 0
PROTALIX BIOTHERAPEUTICS INC COM 74365A101 2,546 1,383,889 SH   SOLE 1,383,889 0 0
PROTALIX BIOTHERAPEUTICS INC NOTE 4.500% 9/1 74365AAB7 3,200 4,000,000 PRN   SOLE 4,000,000 0 0
PROTEON THERAPEUTICS INC COM 74371L109 132 12,700 SH   SOLE 12,700 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 1,700 749,066 SH   SOLE 749,066 0 0
RTI SURGICAL INC COM 74975N105 447 85,918 SH   SOLE 85,918 0 0
SECOND SIGHT MED PRODS INC COM 81362J100 408 39,800 SH   SOLE 39,800 0 0
SPECTRANETICS CORP COM 84760C107 1,458 42,162 SH   SOLE 42,162 0 0
STEREOTAXIS INC COM NEW 85916J409 2,035 1,374,975 SH   SOLE 1,374,975 0 0
SYNERON MEDICAL LTD ORD SHS M87245102 849 90,947 SH   SOLE 90,947 0 0
TARGACEPT INC COM 87611R306 1,224 465,293 SH   SOLE 465,293 0 0
THRESHOLD PHARMACEUTICALS COM NEW 885807206 1,688 530,965 SH   SOLE 530,965 0 0
TREVENA INC COM 89532E109 1,674 280,000 SH   SOLE 280,000 0 0
UNIQURE B.V. NV SHS N90064101 587 39,656 SH   SOLE 39,656 0 0
UROPLASTY INC COM NEW 917277204 1,001 486,062 SH   SOLE 486,062 0 0
VENAXIS INC COM 92262A107 1,165 658,000 SH   SOLE 658,000 0 0
XENOPORT INC COM 98411C100 861 98,190 SH   SOLE 98,190 0 0