The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 7,833 116,581 SH   SOLE 116,581 0 0
ACHILLION PHARMACEUTICALS COM 00448Q201 4,255 480,300 SH   SOLE 480,300 0 0
ACTINIUM PHARMACEUTICALS INC COM 00507W107 239 90,000 SH   SOLE 90,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 2,768 156,842 SH   SOLE 156,842 0 0
AFFIMED THERAPEUTICS BV COM N01045108 390 28,950 SH   SOLE 28,950 0 0
ANTARES PHARMA INC COM 036642106 94 45,000 SH   SOLE 45,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 2,411 157,192 SH   SOLE 157,192 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 359 70,396 SH   SOLE 70,396 0 0
ARCA BIOPHARMA INC COM NEW 00211Y209 653 567,859 SH   SOLE 567,859 0 0
ARENA PHARMACEUTICALS INC COM 040047102 877 189,000 SH   SOLE 189,000 0 0
ASCENDIS PHARMA ADR ADDED 04351P101 1,654 93,541 SH   SOLE 93,541 0 0
ATRICURE INC COM 04963C209 13,518 548,611 SH   SOLE 548,611 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 3,309 221,656 SH   SOLE 221,656 0 0
BIOTELEMETRY INC COM 090672106 2,222 235,645 SH   SOLE 235,645 0 0
BIOTIE THERAPIES ADR 09074D103 200 10,000 SH   SOLE 10,000 0 0
BLUEBIRD BIO INC COM 09609G100 1,010 6,000 SH   SOLE 6,000 0 0
CALADRIUS BIOSCIENCES INC COM 128058104 166 88,900 SH   SOLE 88,900 0 0
CARA THERAPEUTICS INC COM 140755109 1,543 126,956 SH   SOLE 126,956 0 0
CARDICA INC COM 14141R101 742 1,486,004 SH   SOLE 1,486,004 0 0
CAREDX INC COM 14167L103 947 145,627 SH   SOLE 145,627 0 0
CAS MEDICAL SYSTEMS INC COM PAR $0.004 124769209 113 88,522 SH   SOLE 88,522 0 0
CEL SCI CORP COM PAR $0.01 150837508 209 316,500 SH   SOLE 316,500 0 0
CELYAD ADR 151205200 1,561 30,000 SH   SOLE 30,000 0 0
CHECK CAP LTD SHS ADDED M2361E112 385 110,000 SH   SOLE 110,000 0 0
CHECK CAP LTD *W EXP 02/28/202 ADDED M2361E120 96 55,000 SH   SOLE 55,000 0 0
CHEMBIO DIAGNOSTICS INC COM NEW 163572209 129 26,287 SH   SOLE 26,287 0 0
CLOVIS ONCOLOGY INC COM 189464100 2,029 23,090 SH   SOLE 23,090 0 0
COGENTIX MEDICAL INC COM 19243A104 572 353,181 SH   SOLE 353,181 0 0
CORBUS PHARMACEUTICALS HLDGS COM 21833P103 113 36,590 SH   SOLE 36,590 0 0
CYNAPSUS THERAPEUTICS INC COM 23257Y156 559 33,995 SH   SOLE 33,995 0 0
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR 23257Y859 915 44,824 SH   SOLE 44,824 0 0
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR 23257Y859 815 50,000 SH   SOLE 50,000 0 0
CYTRX CORP COM PAR $.001 232828509 1,119 300,813 SH   SOLE 300,813 0 0
DERMA SCIENCES INC COM PAR $.01 249827502 2,677 373,918 SH   SOLE 373,918 0 0
DERMIRA INC COM 24983L104 996 56,736 SH   SOLE 56,736 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 1,211 86,800 SH   SOLE 86,800 0 0
DISCOVERY LABORATORIES INC COM NEW 254668403 3,261 4,794,874 SH   SOLE 4,794,874 0 0
ENCISION INC COM 29254Q104 584 1,062,500 SH   SOLE 1,062,500 0 0
ESSA PHARMA INC COM 29668H104 2,626 231,200 SH   SOLE 231,200 0 0
EXACTECH INC COM 30064E109 659 31,636 SH   SOLE 31,636 0 0
GENVEC INC COM NEW 37246C307 204 100,000 SH   SOLE 100,000 0 0
INSULET CORP COM 45784P101 3,285 106,018 SH   SOLE 106,018 0 0
INSULET CORP NOTE 2.000% 6/1 45784PAD3 2,338 2,407,000 PRN   SOLE 2,407,000 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 483 2,000 SH   SOLE 2,000 0 0
IRONWOOD PHARMA NOTE 2.25% 15-Jun-2022 144A SR UNSECURED CONV 46333XAC2 396 400,000 PRN   SOLE 400,000 0 0
JOHNSON AND JOHNSON COM 478160104 916 9,400 SH   SOLE 9,400 0 0
LIPOCINE INC COM NEW 53630X104 729 85,000 SH   SOLE 85,000 0 0
LOXO ONCOLOGY INC COM 548862101 221 12,245 SH   SOLE 12,245 0 0
LUMENIS LTD SHS CL B M6778Q121 426 31,072 SH   SOLE 31,072 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 259 22,319 SH   SOLE 22,319 0 0
MASIMO CORPORATION COM 574795100 1,782 46,010 SH   SOLE 46,010 0 0
NEOTHETICS INC COM 64066G101 1,658 184,187 SH   SOLE 184,187 0 0
NIVALIS THERAPEUTICS INC COM 65481J109 227 15,000 SH   SOLE 15,000 0 0
NOVADAQ TECHNOLOGIES INC COM 66987G102 1,233 101,841 SH   SOLE 101,841 0 0
NUVASIVE INC NOTE 2.750% 7/0 670704AC9 968 760,000 PRN   SOLE 760,000 0 0
NXSTAGE MEDICAL INC COM 67072V103 5,236 366,554 SH   SOLE 366,554 0 0
ONCOTHYREON INC COM 682324108 135 36,180 SH   SOLE 36,180 0 0
OTONOMY INC COM 68906L105 2,563 111,466 SH   SOLE 111,466 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 344 125,000 SH   SOLE 125,000 0 0
PROTALIX BIOTHERAPEUTICS INC COM 74365A101 2,400 1,230,789 SH   SOLE 1,230,789 0 0
PROTALIX BIOTHERAPEUTICS INC NOTE 4.500% 9/1 74365AAB7 3,196 4,000,000 PRN   SOLE 4,000,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 3,562 1,109,740 SH   SOLE 1,109,740 0 0
RTI SURGICAL INC COM 74975N105 555 85,918 SH   SOLE 85,918 0 0
SCYNEXIS INC COM 811292101 1,419 161,382 SH   SOLE 161,382 0 0
SPECTRANETICS CORP COM 84760C107 916 39,812 SH   SOLE 39,812 0 0
STEREOTAXIS INC COM NEW 85916J409 1,977 1,372,862 SH   SOLE 1,372,862 0 0
SYNERGY PHARMACEUTICALS COM 871639308 2,636 317,563 SH   SOLE 317,563 0 0
SYNERON MEDICAL LTD ORD SHS M87245102 966 90,947 SH   SOLE 90,947 0 0
TANDEM DIABETES CARE INC COM 875372104 390 35,992 SH   SOLE 35,992 0 0
TARGACEPT INC COM 87611R306 1,294 463,914 SH   SOLE 463,914 0 0
TRANSITION THERAPEUTICS INC COM NEW 893716209 124 59,222 SH   SOLE 59,222 0 0
UNIQURE B.V. NV SHS N90064101 1,080 40,000 SH   SOLE 40,000 0 0
VENAXIS INC COM 92262A107 295 658,000 SH   SOLE 658,000 0 0
XENOPORT INC COM 98411C100 3,255 531,032 SH   SOLE 531,032 0 0
ZOGENIX INC COM 98978L204 1,434 853,700 SH   SOLE 853,700 0 0
ZS PHARMA INC COM 98979G105 3,515 67,100 SH   SOLE 67,100 0 0