The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   1,210,292 66,978 SH   SOLE   66,978 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   143,495,922 5,991,479 SH   SOLE   5,991,479 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103   2,252,500 5,000,000 SH   SOLE   5,000,000 0 0
ALECTOR INC COM 014442107   24,379,853 4,056,548 SH   SOLE   4,056,548 0 0
ALIGOS THERAPEUTICS INC COM 01626L105   3,833,858 3,948,360 SH   SOLE   3,948,360 0 0
ALLAKOS INC COM 01671P100   3,265,204 748,900 SH   SOLE   748,900 0 0
ALLOGENE THERAPEUTICS INC COM 019770106   22,306,354 4,488,200 SH   SOLE   4,488,200 0 0
ANAPTYSBIO INC COM 032724106   152,977,628 7,521,024 SH   SOLE   7,521,024 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   496,645,042 5,451,647 SH   SOLE   5,451,647 0 0
ARVINAS INC COM 04335A105   99,721,498 4,017,788 SH   SOLE   4,017,788 0 0
ATEA PHARMACEUTICALS INC COM 04683R106   26,164,520 6,995,861 SH   SOLE   6,995,861 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   113,652,560 1,798,300 SH   SOLE   1,798,300 0 0
CAREMAX INC *W EXP 06/08/202 14171W111   311,000 100,000 SH   SOLE   100,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   34,780,242 5,618,779 SH   SOLE   5,618,779 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   23,971,339 1,330,263 SH   SOLE   1,330,263 0 0
DYNE THERAPEUTICS INC COM 26818M108   8,985,386 798,701 SH   SOLE   798,701 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   27,072,254 3,493,194 SH   SOLE   3,493,194 0 0
GALAPAGOS NV SPON ADR 36315X101   234,049,857 5,756,268 SH   SOLE   5,756,268 0 0
GENERATION BIO CO COM 37148K100   11,257,769 2,046,867 SH   SOLE   2,046,867 0 0
GRAPHITE BIO INC COM 38870X104   22,199,960 8,538,446 SH   SOLE   8,538,446 0 0
HOOKIPA PHARMA INC COM 43906K100   4,043,621 4,595,024 SH   SOLE   4,595,024 0 0
JANUX THERAPEUTICS INC COM 47103J105   5,372,243 452,590 SH   SOLE   452,590 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   45,671,912 368,411 SH   SOLE   368,411 0 0
JOHNSON & JOHNSON COM 478160104   281,384,000 1,700,000 SH Call SOLE   1,700,000 0 0
KRONOS BIO INC COM 50107A104   562,062 326,780 SH   SOLE   326,780 0 0
KURA ONCOLOGY INC COM 50127T109   61,436,695 5,806,871 SH   SOLE   5,806,871 0 0
KURA ONCOLOGY INC COM 50127T109   5,290,000 500,000 SH Call SOLE   500,000 0 0
MORPHIC HLDG INC COM 61775R105   220,546,446 3,846,964 SH   SOLE   3,846,964 0 0
NEWAMSTERDAM PHARMA COMPANY *W EXP 11/22/202 N62509117   792,647 66,665 SH   SOLE   66,665 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105   16,667,992 6,435,518 SH   SOLE   6,435,518 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119   1,733,999 963,333 SH   SOLE   963,333 0 0
NUVATION BIO INC COM CL A 67080N101   25,013,777 13,896,543 SH   SOLE   13,896,543 0 0
ORIC PHARMACEUTICALS INC COM 68622P109   26,524,208 3,418,068 SH   SOLE   3,418,068 0 0
OVID THERAPEUTICS INC COM 690469101   20,065,072 6,117,400 SH   SOLE   6,117,400 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107   10,024,000 700,000 SH   SOLE   700,000 0 0
POSEIDA THERAPEUTICS INC COM 73730P108   1,190,281 676,296 SH   SOLE   676,296 0 0
PRELUDE THERAPEUTICS INC COM 74065P101   5,208,534 1,157,452 SH   SOLE   1,157,452 0 0
PRIME MEDICINE INC COM 74168J101   8,790,000 600,000 SH   SOLE   600,000 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109   4,827,626 2,980,016 SH   SOLE   2,980,016 0 0
PROTHENA CORP PLC SHS G72800108   790,974,638 11,584,280 SH   SOLE   11,584,280 0 0
RELAY THERAPEUTICS INC COM 75943R102   52,297,629 4,163,824 SH   SOLE   4,163,824 0 0
REVOLUTION MEDICINES INC COM 76155X100   192,565,225 7,198,700 SH   SOLE   7,198,700 0 0
SAREPTA THERAPEUTICS INC COM 803607100   419,234,587 3,660,798 SH   SOLE   3,660,798 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   90,726,654 3,460,208 SH   SOLE   3,460,208 0 0
SURROZEN INC *W EXP 08/01/203 86889P117   36,666 66,665 SH   SOLE   66,665 0 0
TANGO THERAPEUTICS INC COM 87583X109   13,436,418 4,047,114 SH   SOLE   4,047,114 0 0
TEMPEST THERAPEUTICS INC COM 87978U108   1,426,761 1,123,434 SH   SOLE   1,123,434 0 0
THIRD HARMONIC BIO INC COM 88427A107   10,047,032 2,088,780 SH   SOLE   2,088,780 0 0
TSCAN THERAPEUTICS INC COM 89854M101   12,500,000 5,000,000 SH   SOLE   5,000,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   44,099,755 3,851,507 SH   SOLE   3,851,507 0 0
XENCOR INC COM 98401F105   131,904,425 5,282,516 SH   SOLE   5,282,516 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107   8,463,000 300,000 SH   SOLE   300,000 0 0
ZYMEWORKS INC COM 98985Y108   116,099,767 13,437,473 SH   SOLE   13,437,473 0 0