The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABCAM PLC ADS 000380204 BBG00XRJJM98 58,850,350 2,405,000 SH   SOLE   2,405,000 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 BBG001SNNWL7 72,313,120 908,000 SH   SOLE   908,000 0 0
ACCOLADE INC COM 00437E102 BBG00S2L1ZR1 37,985,400 2,820,000 SH   SOLE   2,820,000 0 0
ACELRX PHARMACEUTICALS INC COM NEW 00444T209 BBG001TFZCK5 351,271 316,460 SH   SOLE   316,460 0 0
ACELYRIN INC COM 00445A100 BBG00YJKJ8J2 2,965,208 141,876 SH   SOLE   141,876 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 BBG003LF0QS8 41,084,374 3,961,849 SH   SOLE   3,961,849 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 BBG008G65WD1 2,578,757 2,787,845 SH   SOLE   2,787,845 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 BBG0067L94C1 1,537,965 3,413,906 SH   SOLE   3,413,906 0 0
AGILON HEALTH INC COM 00857U107 BBG00HCYVQR3 143,618,550 8,282,500 SH   SOLE   8,282,500 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 BBG001T8R687 76,072,249 2,686,167 SH   SOLE   2,686,167 0 0
AKERO THERAPEUTICS INC COM 00973Y108 BBG00L9211Z7 72,404,704 1,550,754 SH   SOLE   1,550,754 0 0
ALIGN TECHNOLOGY INC COM 016255101 BBG001SCF1B9 76,739,880 217,000 SH   SOLE   217,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 BBG001S7FTC8 65,529,300 345,000 SH   SOLE   345,000 0 0
ALTIMMUNE INC COM NEW 02155H200 BBG001SNS461 788,090 223,255 SH   SOLE   223,255 0 0
AMICUS THERAPEUTICS INC COM 03152W109 BBG001SN96V9 13,361,403 1,063,806 SH   SOLE   1,063,806 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 BBG00DP10YW1 33,317,367 1,544,616 SH   SOLE   1,544,616 0 0
ANAPTYSBIO INC COM 032724106 BBG0026ZDHT8 6,948,897 341,637 SH   SOLE   341,637 0 0
APPLIED THERAPEUTICS INC COM 03828A101 BBG001SMJMY2 999,412 780,791 SH   SOLE   780,791 0 0
ARGENX SE SPONSORED ADR 04016X101 BBG00GHB88Y8 136,405,500 350,000 SH   SOLE   350,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 BBG007R7VP72 37,975,875 425,500 SH   SOLE   425,500 0 0
ATRECA INC CL A COM 04965G109 BBG003FJ19C1 355,279 362,530 SH   SOLE   362,530 0 0
AURA BIOSCIENCES INC COM 05153U107 BBG00226DGP2 12,593,999 1,019,757 SH   SOLE   1,019,757 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 BBG001S68013 4,641,947 479,540 SH   SOLE   479,540 0 0
AZENTA INC COM 114340102 BBG001S8F1B8 21,934,932 469,900 SH   SOLE   469,900 0 0
BEAM THERAPEUTICS INC COM 07373V105 BBG00KXC8655 3,557,960 111,430 SH   SOLE   111,430 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 BBG001S7K151 17,580,239 2,497,193 SH   SOLE   2,497,193 0 0
BIOHAVEN LTD COM G1110E107 BBG017BXV3R8 9,606,846 401,624 SH   SOLE   401,624 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 BBG001S76R05 22,926,860 264,500 SH   SOLE   264,500 0 0
BIOMEA FUSION INC COM 09077A106 BBG00YS4WDD8 18,369,911 836,898 SH   SOLE   836,898 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 BBG00MS4Y0X8 2,844,327 563,233 SH   SOLE   563,233 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 BBG001V11BV0 138,197,670 2,186,672 SH   SOLE   2,186,672 0 0
BOSTON SCIENTIFIC CORP COM 101137107 BBG001S63L94 14,469,075 267,500 SH   SOLE   267,500 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 BBG001S7QN20 14,305,397 421,615 SH   SOLE   421,615 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 BBG00VCYVLJ2 79,917,390 2,513,916 SH   SOLE   2,513,916 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 BBG001T20HH5 15,225,078 396,280 SH   SOLE   396,280 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 BBG001T535S9 13,968,500 650,000 SH   SOLE   650,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104 BBG00LPXKF34 17,533,846 5,513,788 SH   SOLE   5,513,788 0 0
COMPUGEN LTD ORD M25722105 BBG001S5PQC7 1,470,589 1,289,990 SH   SOLE   1,289,990 0 0
CONMED CORP COM 207410101 BBG001S5PZH2 27,857,450 205,000 SH   SOLE   205,000 0 0
CYTOKINETICS INC COM NEW 23282W605 BBG001SGMVF2 14,600,712 447,600 SH   SOLE   447,600 0 0
DESIGN THERAPEUTICS INC COM 25056L103 BBG00SNC49W7 2,900,463 460,391 SH   SOLE   460,391 0 0
DEXCOM INC COM 252131107 BBG001SKZG99 63,034,155 490,500 SH   SOLE   490,500 0 0
DISC MEDICINE INC COM 254604101 BBG00W9MJL04 16,137,979 363,468 SH   SOLE   363,468 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 BBG001S7HTB7 23,433,753 1,813,758 SH   SOLE   1,813,758 0 0
EDAP TMS S A SPONSORED ADR 268311107 BBG001SB3ML7 10,937,686 1,186,300 SH   SOLE   1,186,300 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 BBG001SF2288 60,927,747 645,900 SH   SOLE   645,900 0 0
ESSA PHARMA INC COM NEW 29668H708 BBG0080GLFK7 1,790,956 663,317 SH   SOLE   663,317 0 0
EVOLENT HEALTH INC CL A 30050B101 BBG005CHLMB3 115,246,050 3,803,500 SH   SOLE   3,803,500 0 0
EXACT SCIENCES CORP COM 30063P105 BBG001SGCLB9 88,594,650 943,500 SH   SOLE   943,500 0 0
FATE THERAPEUTICS INC COM 31189P102 BBG001T888S2 2,914,143 612,215 SH   SOLE   612,215 0 0
FRESHPET INC COM 358039105 BBG001V04FM0 43,599,125 662,500 SH   SOLE   662,500 0 0
FULCRUM THERAPEUTICS INC COM 359616109 BBG00DDY1RM7 2,401,321 727,673 SH   SOLE   727,673 0 0
GAMIDA CELL LTD SHS M47364100 BBG00M4RGJ53 1,379,994 715,023 SH   SOLE   715,023 0 0
GOSSAMER BIO INC COM 38341P102 BBG00MVWLMC1 1,320,329 1,100,274 SH   SOLE   1,100,274 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0   2,888,997 9,573,000 PRN   SOLE   9,573,000 0 0
GUARDANT HEALTH INC COM 40131M109 BBG006D97VZ8 7,160,000 200,000 SH   SOLE   200,000 0 0
HEALTH CATALYST INC COM 42225T107 BBG00LDPZMT5 11,623,750 929,900 SH   SOLE   929,900 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 BBG001T9M4T2 50,910,750 495,000 SH   SOLE   495,000 0 0
HUMANA INC COM 444859102 BBG001S5S1X6 210,151,100 470,000 SH   SOLE   470,000 0 0
ICOSAVAX INC COM 45114M109 BBG00QHK2J96 8,623,301 868,409 SH   SOLE   868,409 0 0
IDEXX LABS INC COM 45168D104 BBG001S5S4Y9 97,683,735 194,500 SH   SOLE   194,500 0 0
IMMATICS N.V SHS N44445109 BBG00VTL2J09 29,267,102 2,536,144 SH   SOLE   2,536,144 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 BBG00YYCXG54 181,583,464 3,028,410 SH   SOLE   3,028,410 0 0
IMMUNOGEN INC COM 45253H101 BBG001S6CTN1 2,125,139 112,620 SH   SOLE   112,620 0 0
INOZYME PHARMA INC COM 45790W108 BBG00J7QJMD0 19,094,428 3,428,084 SH   SOLE   3,428,084 0 0
INSULET CORP COM 45784P101 BBG001SRF439 161,182,060 559,000 SH   SOLE   559,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 BBG001S7XR78 102,069,090 298,500 SH   SOLE   298,500 0 0
INVITAE CORP COM 46185L103 BBG005DJFD52 1,865,059 1,650,495 SH   SOLE   1,650,495 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 BBG001TSQV70 32,281,824 309,450 SH   SOLE   309,450 0 0
KARUNA THERAPEUTICS INC COM 48576A100 BBG00NN875H9 107,021,330 493,527 SH   SOLE   493,527 0 0
KINNATE BIOPHARMA INC COM 49705R105 BBG00R4SGVH0 2,263,328 746,973 SH   SOLE   746,973 0 0
KRYSTAL BIOTECH INC COM 501147102 BBG00HDGRHJ5 4,097,377 34,901 SH   SOLE   34,901 0 0
KYMERA THERAPEUTICS INC COM 501575104 BBG00SDHC8F9 34,198,797 1,487,551 SH   SOLE   1,487,551 0 0
LEAP THERAPEUTICS INC COM NEW 52187K200 BBG00DQ929Z3 3,363,238 1,074,517 SH   SOLE   1,074,517 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 BBG00TTGH6N2 31,634,033 458,265 SH   SOLE   458,265 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 BBG01138DHT2 26,477,000 2,900,000 SH   SOLE   2,900,000 0 0
MACROGENICS INC COM 556099109 BBG001S9C8R7 6,008,564 1,123,096 SH   SOLE   1,123,096 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 BBG001SNKQ42 46,019,358 199,218 SH   SOLE   199,218 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107 BBG00KFWZCX7 9,295,956 7,042,391 SH   SOLE   7,042,391 0 0
MERSANA THERAPEUTICS INC COM 59045L106 BBG001TZ57P0 11,196,308 3,403,133 SH   SOLE   3,403,133 0 0
MERUS N V COM N5749R100 BBG00B8LXMT4 12,599,721 478,531 SH   SOLE   478,531 0 0
MINERALYS THERAPEUTICS INC COM 603170101 BBG00ZXN1GR9 19,905,739 1,167,492 SH   SOLE   1,167,492 0 0
MIRATI THERAPEUTICS INC COM 60468T105 BBG001SF6HK7 40,525,106 1,121,647 SH   SOLE   1,121,647 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 BBG00MH7T2N6 47,102,363 1,820,733 SH   SOLE   1,820,733 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1   1,276,050 1,000,000 PRN   SOLE   1,000,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 BBG001S8W4X9 120,656,850 1,279,500 SH   SOLE   1,279,500 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7   462,430 500,000 PRN   SOLE   500,000 0 0
NEVRO CORP COM 64157F103 BBG001V0KW81 30,793,788 1,211,400 SH   SOLE   1,211,400 0 0
NKARTA INC COM 65487U108 BBG00JXHS9H6 726,140 331,571 SH   SOLE   331,571 0 0
NOVAVAX INC COM NEW 670002401 BBG001SGL8G3 3,987,681 536,700 SH   SOLE   536,700 0 0
NOVOCURE LTD ORD SHS G6674U108 BBG009XW8QY0 5,187,500 125,000 SH   SOLE   125,000 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119   22,167 134,028 SH   SOLE   134,028 0 0
OLINK HLDG AB SPONSORED ADS 680710100 BBG00ZHZXZ84 31,012,500 1,654,000 SH   SOLE   1,654,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 BBG001S77N12 41,472,450 1,035,000 SH   SOLE   1,035,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 BBG001SQHLP7 3,832,222 1,734,037 SH   SOLE   1,734,037 0 0
PENUMBRA INC COM 70975L107 BBG001TRHPB0 125,925,960 366,000 SH   SOLE   366,000 0 0
PHREESIA INC COM 71944F106 BBG001TG2W25 40,468,050 1,305,000 SH   SOLE   1,305,000 0 0
PLIANT THERAPEUTICS INC COM 729139105 BBG00C8083P2 8,900,925 491,221 SH   SOLE   491,221 0 0
PROTHENA CORP PLC SHS G72800108 BBG00393H6N0 51,446,385 753,462 SH   SOLE   753,462 0 0
PULMONX CORP COM 745848101 BBG001T4HJ52 8,552,964 652,400 SH   SOLE   652,400 0 0
RELAY THERAPEUTICS INC COM 75943R102 BBG00DSS08L8 8,465,013 673,966 SH   SOLE   673,966 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 BBG00JVRSRD0 7,499,294 1,143,185 SH   SOLE   1,143,185 0 0
REVOLUTION MEDICINES INC COM 76155X100 BBG00829F4Q7 18,797,546 702,712 SH   SOLE   702,712 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 BBG007DLZ629 26,336,558 1,597,123 SH   SOLE   1,597,123 0 0
SAREPTA THERAPEUTICS INC COM 803607100 BBG001S6KJC6 48,671,000 425,000 SH   SOLE   425,000 0 0
SEAGEN INC COM 81181C104 BBG001S9M4Q6 77,022,492 400,200 SH   SOLE   400,200 0 0
SELECT SECTOR SPDR TR SBI HEALTHCARE 81369Y209 BBG001S7SCQ6 26,546,000 200,000 SH   SOLE   200,000 0 0
SHOCKWAVE MED INC COM 82489T104 BBG005XVXMM4 32,850,691 115,100 SH   SOLE   115,100 0 0
SPERO THERAPEUTICS INC COM 84833T103 BBG00HXSJ1S1 970,823 669,533 SH   SOLE   669,533 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 BBG00HYZ1559 5,865,469 2,728,125 SH   SOLE   2,728,125 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 BBG002NDK348 680,992 536,214 SH   SOLE   536,214 0 0
THESEUS PHARMACEUTICALS INC COM 88369M101 BBG00Z0GRC64 4,080,280 437,329 SH   SOLE   437,329 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 BBG001SL72C5 23,465,779 1,527,720 SH   SOLE   1,527,720 0 0
TRAVERE THERAPEUTICS INC NOTE 2.500% 9/1 761299AB2   2,856,545 3,250,000 PRN   SOLE   3,250,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 BBG001V2MJJ2 63,856,329 1,384,269 SH   SOLE   1,384,269 0 0
UNITEDHEALTH GROUP INC COM 91324P102 BBG001S6WCJ1 110,547,200 230,000 SH   SOLE   230,000 0 0
VIGIL NEUROSCIENCE INC COM 92673K108 BBG00YGBK4R3 4,436,405 471,958 SH   SOLE   471,958 0 0
VINCERX PHARMA INC COM NEW 92731L106 BBG00RRQXMY1 1,159,235 891,719 SH   SOLE   891,719 0 0
WARBY PARKER INC CL A COM 93403J106 BBG005DWN8L7 15,489,250 1,325,000 SH   SOLE   1,325,000 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 BBG001S5XK22 77,258,940 202,000 SH   SOLE   202,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 BBG002VBMLS5 45,353,077 1,178,002 SH   SOLE   1,178,002 0 0
XILIO THERAPEUTICS INC COM 98422T100 BBG00M4D4XC8 3,774,789 1,440,759 SH   SOLE   1,440,759 0 0
ZAI LAB LTD ADR 98887Q104 BBG00HFX3P04 33,897,790 1,222,423 SH   SOLE   1,222,423 0 0