The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   50,200,393 2,778,107 SH   SOLE   2,778,107 0 0
89BIO INC COM 282559103   9,533,745 503,100 SH   SOLE   503,100 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209   18,837,696 3,916,361 SH   SOLE   3,916,361 0 0
AGENUS INC COM NEW 00847G705   48,000,000 30,000,000 SH   SOLE   30,000,000 0 0
ALKERMES PLC SHS G01767105   93,900,000 3,000,000 SH   SOLE   3,000,000 0 0
ALLAKOS INC COM 01671P100   995,288 228,277 SH   SOLE   228,277 0 0
ANI PHARMACEUTICALS INC COM 00182C103   27,669,750 514,021 SH   SOLE   514,021 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   14,139,467 1,697,415 SH   SOLE   1,697,415 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   35,700,000 15,000,000 SH   SOLE   15,000,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   27,608,612 384,200 SH   SOLE   384,200 0 0
BEAM THERAPEUTICS INC COM 07373V105   42,061,900 1,317,316 SH   SOLE   1,317,316 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   71,942,028 2,819,045 SH   SOLE   2,819,045 0 0
CENTURY THERAPEUTICS INC COM 15673T100   3,232,339 1,022,892 SH   SOLE   1,022,892 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   5,616,821 678,360 SH   SOLE   678,360 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201   84,726,983 6,557,816 SH   SOLE   6,557,816 0 0
DYNE THERAPEUTICS INC COM 26818M108   28,124,010 2,499,912 SH   SOLE   2,499,912 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   21,312,500 2,750,000 SH   SOLE   2,750,000 0 0
EDITAS MEDICINE INC COM 28106W103   28,424,313 3,453,744 SH   SOLE   3,453,744 0 0
FIBROGEN INC COM 31572Q808   2,064,690 764,700 SH Call SOLE   764,700 0 0
GERON CORP COM 374163103   77,588,801 24,170,966 SH   SOLE   24,170,966 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   5,925,381 499,400 SH   SOLE   499,400 0 0
GUARDANT HEALTH INC COM 40131M109   53,700,000 1,500,000 SH   SOLE   1,500,000 0 0
HERON THERAPEUTICS INC COM 427746102   2,420,577 2,086,704 SH   SOLE   2,086,704 0 0
IMMUNIC INC COM 4525EP101   773,868 308,314 SH   SOLE   308,314 0 0
IMMUNOVANT INC COM 45258J102   102,842,630 5,421,330 SH   SOLE   5,421,330 0 0
INOZYME PHARMA INC COM 45790W108   9,157,197 1,644,021 SH   SOLE   1,644,021 0 0
INSMED INC COM PAR $.01 457669307   137,150,000 6,500,000 SH   SOLE   6,500,000 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   34,069,488 835,446 SH   SOLE   835,446 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   98,035,317 1,548,252 SH   SOLE   1,548,252 0 0
IONIS PHARMACEUTICALS INC COM 462222100   116,281,851 2,834,069 SH   SOLE   2,834,069 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   154,962,500 1,250,000 SH   SOLE   1,250,000 0 0
MINK THERAPEUTICS INC COM 603693102   682,221 324,867 SH   SOLE   324,867 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   5,530,950 108,450 SH   SOLE   108,450 0 0
MORPHIC HLDG INC COM 61775R105   12,426,392 216,752 SH   SOLE   216,752 0 0
NEKTAR THERAPEUTICS COM 640268108   10,338,336 17,973,464 SH   SOLE   17,973,464 0 0
NURIX THERAPEUTICS INC COM 67080M103   29,948,322 2,997,830 SH   SOLE   2,997,830 0 0
NUVATION BIO INC COM CL A 67080N101   13,897,238 7,720,688 SH   SOLE   7,720,688 0 0
ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P101   10,637,101 2,041,670 SH   SOLE   2,041,670 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   19,300,973 1,451,201 SH   SOLE   1,451,201 0 0
PLIANT THERAPEUTICS INC COM 729139105   73,386,000 4,050,000 SH   SOLE   4,050,000 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109   25,200,979 2,781,565 SH   SOLE   2,781,565 0 0
PROTHENA CORP PLC SHS G72800108   17,070,000 250,000 SH Put SOLE   250,000 0 0
RAPT THERAPEUTICS INC COM 75382E109   18,785,291 1,004,561 SH   SOLE   1,004,561 0 0
RELMADA THERAPEUTICS INC COM 75955J402   6,981,032 2,837,818 SH   SOLE   2,837,818 0 0
REPARE THERAPEUTICS INC COM 760273102   28,858,071 2,727,606 SH   SOLE   2,727,606 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   10,733,690 1,951,580 SH   SOLE   1,951,580 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   92,987,526 3,546,435 SH   SOLE   3,546,435 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   110,026,714 2,646,782 SH   SOLE   2,646,782 0 0
TERNS PHARMACEUTICALS INC COM 880881107   9,617,930 1,099,192 SH   SOLE   1,099,192 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   113,203,200 7,370,000 SH   SOLE   7,370,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   67,381,953 3,187,415 SH   SOLE   3,187,415 0 0
VIGIL NEUROSCIENCE INC COM 92673K108   16,670,045 1,773,409 SH   SOLE   1,773,409 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   30,439,353 1,279,502 SH   SOLE   1,279,502 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107   8,471,463 300,300 SH   SOLE   300,300 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101   20,688,600 2,523,000 SH   SOLE   2,523,000 0 0