The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Adicet Bio Inc Com 007002108   5,119,232 2,115,385 SH   DFND 1 0 2,115,385 0
Aeglea Biotherapeutics Inc Com 00773J103   108,225 240,500 SH   DFND 1 0 240,500 0
CubeSmart Com 229663109   9,847,530 220,500 SH   DFND 2 0 220,500 0
Effector Therapeutics Inc Com 28202V108   3,954,133 4,822,114 SH   DFND 1 0 4,822,114 0
Exicure Inc Com New 30205M200   368,943 281,636 SH   DFND 1 0 281,636 0
GDS Hldgs Ltd Sponsored Ads 36165L108   44,758,142 4,072,624 SH   DFND 2,3 0 4,072,624 0
Getty Images Holdings Inc Cl A Com 374275105   48,684,344 9,976,300 SH   DFND 2 0 9,976,300 0
Hillevax Inc Com 43157M102   31,530,035 1,838,486 SH   DFND 1 0 1,838,486 0
Invitation Homes Inc Com 46187W107   16,426,000 477,500 SH   DFND 2 0 477,500 0
Jasper Therapeutics Inc Com 471871103   11,828,553 8,761,891 SH   DFND 1 0 8,761,891 0
Meta Data Limited Sponsored Ads 68276W400   336,408 314,400 SH   DFND 2,3 0 314,400 0
MKS Instrs Inc Com 55306N104   146,581,546 1,355,981 SH   DFND 2,3 0 1,355,981 0
MKS Instrs Inc Com 55306N104   229,901,783 2,126,751 SH   DFND 2 0 2,126,751 0
Molecular Templates Inc Com 608550109   92,000 200,000 SH   DFND 1 0 200,000 0
Nucana Plc Sponsored Adr 67022C106   2,600,000 3,333,333 SH   DFND 1 0 3,333,333 0
Paratek Pharmaceuticals Inc Com 699374302   2,300,900 1,041,131 SH   DFND 1 0 1,041,131 0
Phathom Pharmaceuticals Inc Com 71722W107   50,074,291 3,496,808 SH   DFND 1 0 3,496,808 0
Quidelortho Corp Com 219798105   1,032,450,763 12,460,183 SH   DFND 2 0 12,460,183 0
Reneo Pharmaceuticals Inc Com 75974E103   17,678,168 2,698,957 SH   DFND 1 0 2,698,957 0
Seacor Marine Hldgs Inc Com 78413P101   15,020,895 1,314,164 SH   DFND 2 0 1,314,164 0
Smart Sh Global Ltd Ads 83193E102   4,689,593 4,810,209 SH   DFND 2,3 0 4,810,209 0
Soleno Therapeutics Inc Com 834203309   5,094,385 1,201,506 SH   DFND 1 0 1,201,506 0
Spruce Biosciences Inc Com 85209E109   6,227,514 2,896,518 SH   DFND 1 0 2,896,518 0
Vera Therapeutics Inc Cl A 92337R101   38,766,065 2,416,837 SH   DFND 1 0 2,416,837 0
Verona Pharma Plc Sponsored Ads 925050106   51,877,825 2,457,500 SH   DFND 1 0 2,457,500 0
Vitru Ltd Com G9440D103   100,130,930 6,246,471 SH   DFND 2,3 0 6,246,471 0
ZoomInfo Technologies Inc Common Stock 98980F104   930,860,088 36,662,469 SH   DFND 2 0 36,662,469 0