ZYMOGENETICS INC (ZGEN) [Rocket]

Ownership

ZYMOGENETICS INC (ZGEN)

Portfolio as of:

Name	Shares	Change	Value	% Port	% OS	Hist	Date
BB BIOTECH AG	7,000,000	0	29,540,000	3.48	8.16	Hist	06/30/2010
VANGUARD GROUP INC	2,392,348	11,014	23,325,000	0.00	2.79	Hist	09/30/2010
WATER ISLAND CAPITAL LLC	1,904,806	1,904,806	18,572,000	1.36	2.22	Hist	09/30/2010
WELLINGTON MANAGEMENT GROUP LLP	4,179,939	-2,118,973	17,640,000	0.01	4.88	Hist	06/30/2010
BlackRock Institutional Trust Company, N.A.	1,368,673	-62,767	13,345,000	0.00	1.60	Hist	09/30/2010
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS	1,283,000	1,283,000	12,509,000	0.05	1.50	Hist	09/30/2010
FMR LLC	2,917,700	-2,914,400	12,313,000	0.00	3.40	Hist	06/30/2010
ALPINE ASSOCIATES ADVISORS	1,067,000	1,067,000	10,403,000	0.36	1.24	Hist	09/30/2010
DIMENSIONAL FUND ADVISORS LP	1,031,628	-125,525	10,058,000	0.01	1.20	Hist	09/30/2010
Flynn James E	1,500,000	0	9,585,000			Hist	12/31/2009
Redmile Group, LLC	764,600	764,600	7,455,000	4.26	0.89	Hist	09/30/2010
TIG Advisors, LLC	734,258	734,258	7,159,000	1.06	0.86	Hist	09/30/2010
SCOGGIN MANAGEMENT LP	520,000	520,000	5,070,000	0.50	0.61	Hist	09/30/2010
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	450,287	-3,225,354	4,390,000	0.26	0.53	Hist	09/30/2010
JENNISON ASSOCIATES LLC	950,000	0	4,009,000	0.01	1.11	Hist	06/30/2010
Trafalgar Asset Managers Ltd	411,000	411,000	4,007,250	3.14	0.48	Hist	09/30/2010
BROWN INVESTMENT ADVISORY & TRUST CO	529,633	711	3,384,000	0.10	0.76	Hist	12/31/2009
SG Americas Securities, LLC	345,900	332,254	3,373,000	0.02	0.40	Hist	09/30/2010
TIAA CREF INVESTMENT MANAGEMENT LLC	303,485	-109,350	2,959,000	0.00	0.35	Hist	09/30/2010
Manikay Partners, LLC	300,000	300,000	2,925,000	0.49	0.35	Hist	09/30/2010
DEUTSCHE BANK AG\	298,684	-387,323	2,912,000	0.00	0.35	Hist	09/30/2010
Granahan Investment Management, LLC	638,460	-1,850	2,694,000	0.11	0.74	Hist	06/30/2010
QS BATTERYMARCH FINANCIAL MANAGEMENT, INC	262,783	-10,020	2,563,000	0.03		Hist	11/11/2010
DAFNA Capital Management LLC	251,738	251,738	2,454,000	5.53	0.29	Hist	09/30/2010
BARCLAYS PLC	247,991	143,294	2,418,000	0.00	0.29	Hist	09/30/2010
NORDEA INVESTMENT MANAGEMENT AB	571,153	0	2,359,000	0.03	0.67	Hist	06/30/2010
BAILARD, INC.	240,000	99,500	2,340,000	0.55	0.28	Hist	09/30/2010
TFS CAPITAL LLC	238,380	186,620	2,324,000	0.21	0.28	Hist	09/30/2010
FIRST NEW YORK SECURITIES LLC /NY	198,900	198,900	1,938,000	0.20	0.23	Hist	09/30/2010
FNY Managed Accounts LLC	195,000	195,000	1,901,000	1.49	0.23	Hist	09/30/2010
DIAMONDBACK CAPITAL MANAGEMENT, LLC	364,400	364,400	1,538,000	0.05	0.43	Hist	06/30/2010
UBS AG	152,950	147,489	1,491,270	0.00	0.18	Hist	09/30/2010
CITADEL L P	244,059	231,935	1,474,000	0.00		Hist	09/30/2009
DekaBank Deutsche Girozentrale	235,900	0	1,381,000	0.02	0.34	Hist	09/30/2009
BlackRock Investment Management, LLC	126,092	29,640	1,229,000	0.00	0.15	Hist	09/30/2010
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