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Jupiter Investment Management Ltd
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,164 | 30,423 | 54,916,000 | 17,144,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 158,741 | 693 | 37,772,000 | 3,168,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 158,048 | 54,127 | 34,604,000 | 16,998,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 103,921 | -439,480 | 17,606,000 | -82,042,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 543,401 | -363,443 | 99,648,000 | -67,165,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 906,844 | 166,393 | 166,813,000 | 44,113,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 740,451 | -677,397 | 122,700,000 | -150,576,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,417,848 | -282,358 | 273,276,000 | -15,691,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,700,206 | 307,536 | 288,967,000 | 61,990,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,392,670 | -35,457 | 226,977,000 | 12,958,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,428,127 | 226,097 | 214,019,000 | 31,263,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,202,030 | 6,575 | 182,756,000 | 28,698,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,195,455 | 1,114,939 | 154,058,000 | 145,254,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 80,516 | 80,516 | 8,804,000 | 8,804,000 | $109.34 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -49,672 | 0 | -4,331,000 | |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 49,672 | -3,084 | 4,331,000 | 2,175,000 | $87.19 |
| 03/31/2010 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 52,756 | -109,944 | 2,156,000 | -4,010,000 | $40.87 |
| 09/30/2009 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 162,700 | 12,357 | 6,166,000 | 808,000 | $37.90 |
| 06/30/2009 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 150,343 | -41,797 | 5,358,000 | -162,000 | $35.64 |
| 03/31/2009 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 192,140 | 192,140 | 5,520,000 | 5,520,000 | $28.73 |
| 06/30/2005 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -39,200 | 0 | -367,000 | |
| 03/31/2005 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 39,200 | 39,200 | 367,000 | 367,000 | $9.36 |
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