News + Filings Holdings
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TWO SIGMA ADVISERS, LP
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 214,400 | 154,000 | 75,449,504,000 | 56,419,276,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 60,400 | 42,600 | 19,030,228,000 | 13,889,944,000 | $315,070.00 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 17,800 | -5,200 | 5,140,284,000 | 5,133,625,000 | $288,780.00 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 23,000 | -1,700 | 6,659,000 | -301,000 | $289.52 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 24,700 | 6,900 | 6,960,000 | 2,315,000 | $281.78 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 17,800 | 5,500 | 4,645,000 | 1,944,000 | $260.96 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 12,300 | -770,400 | 2,701,000 | -139,273,000 | $219.59 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 782,700 | 781,700 | 141,974,000 | 141,772,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,000 | 1,000 | 202,000 | 202,000 | $202.00 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -262,837 | 0 | -62,119,000 | |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 262,837 | -514,800 | 62,119,000 | -149,492,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 777,637 | -438,275 | 211,611,000 | -141,380,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,215,912 | 113,900 | 352,991,000 | 90,767,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,102,012 | -102,700 | 262,224,000 | -1,548,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,204,712 | 301,100 | 263,772,000 | 110,682,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 903,612 | -32,100 | 153,090,000 | -18,501,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 935,712 | -67,700 | 171,591,000 | -12,987,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,003,412 | 258,400 | 184,578,000 | 61,122,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 745,012 | 219,000 | 123,456,000 | 22,072,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 526,012 | 192,600 | 101,384,000 | 44,717,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 333,412 | -479,800 | 56,667,000 | -75,870,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 813,212 | -414,200 | 132,537,000 | -51,403,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,227,412 | 368,162 | 183,940,000 | 53,300,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 859,250 | -3,351 | 130,640,000 | 19,477,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 862,601 | -295,767 | 111,163,000 | -15,505,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,158,368 | 63,539 | 126,668,000 | 46,012,000 | $109.35 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,094,829 | 834,476 | 80,656,000 | 57,951,000 | $73.67 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 260,353 | 28,067 | 22,705,000 | 2,724,000 | $87.21 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 232,286 | 232,286 | 19,981,000 | 19,981,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 945,666 | 945,666 | 75,171,000 | 75,171,000 | $79.49 |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 272,690 | 272,690 | 34,313,000 | 34,313,000 | $125.83 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 301,296 | 287,800 | 32,050,000 | 30,384,000 | $106.37 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 13,496 | 13,496 | 1,666,000 | 1,666,000 | $123.44 |
| 06/30/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -10,086 | 0 | -422,000 | |
| 03/31/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -10,086 | 0 | -422,000 | |
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