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RENAISSANCE TECHNOLOGIES LLC
> LYRA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Lyra Therapeutics, Inc. | LYRA | 71,000 | 23,149 | 292,000 | 196,000 | $4.11 |
| 03/31/2023 | Lyra Therapeutics, Inc. | LYRA | 47,851 | 7,851 | 96,000 | -104,000 | $2.01 |
| 09/30/2022 | Lyra Therapeutics, Inc. | LYRA | 40,000 | -1,000 | 200,000 | -32,000 | $5.00 |
| 06/30/2022 | Lyra Therapeutics, Inc. | LYRA | 41,000 | 23,500 | 232,000 | 162,000 | $5.66 |
| 03/31/2022 | Lyra Therapeutics, Inc. | LYRA | 17,500 | -34,500 | 70,000 | -157,000 | $4.00 |
| 12/31/2021 | Lyra Therapeutics, Inc. | LYRA | 52,000 | 52,000 | 227,000 | 227,000 | $4.37 |
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