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MARSHALL WACE, LLP
> BCYC
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | BICYCLE THERAPEUTICS plc | BCYC | 9,271 | 0 | 236,596,000 | -37,826,000 | $25,520.01 |
| 12/31/2022 | BICYCLE THERAPEUTICS plc | BCYC | 9,271 | 0 | 274,422,000 | 274,206,000 | $29,600.04 |
| 09/30/2022 | BICYCLE THERAPEUTICS plc | BCYC | 9,271 | -70,852 | 216,000 | -1,128,000 | $23.30 |
| 06/30/2022 | BICYCLE THERAPEUTICS plc | BCYC | 80,123 | 69,504 | 1,344,000 | 878,000 | $16.77 |
| 03/31/2022 | BICYCLE THERAPEUTICS plc | BCYC | 10,619 | -39,779 | 466,000 | -2,601,000 | $43.88 |
| 12/31/2021 | BICYCLE THERAPEUTICS plc | BCYC | 50,398 | 42,704 | 3,067,000 | 2,747,000 | $60.86 |
| 09/30/2021 | BICYCLE THERAPEUTICS plc | BCYC | 7,694 | 0 | 320,000 | 86,000 | $41.59 |
| 06/30/2021 | BICYCLE THERAPEUTICS plc | BCYC | 7,694 | -14,223 | 234,000 | -421,000 | $30.41 |
| 03/31/2021 | BICYCLE THERAPEUTICS plc | BCYC | 21,917 | 21,917 | 655,000 | 655,000 | $29.89 |
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