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Point72 Asset Management, L.P.
> APLT
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Applied Therapeutics Inc. | APLT | 474,929 | -245,009 | 607,909,000 | 23,967,000 | $1,280.00 |
| 03/31/2023 | Applied Therapeutics Inc. | APLT | 719,938 | 0 | 583,942,000 | 36,789,000 | $811.10 |
| 12/31/2022 | Applied Therapeutics Inc. | APLT | 719,938 | -1,000,000 | 547,153,000 | 545,553,000 | $760.00 |
| 09/30/2022 | Applied Therapeutics Inc. | APLT | 1,719,938 | -1,115,062 | 1,600,000 | -1,088,000 | $0.93 |
| 06/30/2022 | Applied Therapeutics Inc. | APLT | 2,835,000 | 286,000 | 2,688,000 | -2,690,000 | $0.95 |
| 03/31/2022 | Applied Therapeutics Inc. | APLT | 2,549,000 | 1,435,000 | 5,378,000 | -4,592,000 | $2.11 |
| 12/31/2021 | Applied Therapeutics Inc. | APLT | 1,114,000 | 621,500 | 9,970,000 | -264,000 | $8.95 |
| 06/30/2021 | Applied Therapeutics Inc. | APLT | 492,500 | 194,200 | 10,234,000 | 4,639,000 | $20.78 |
| 03/31/2021 | Applied Therapeutics Inc. | APLT | 298,300 | 138,300 | 5,595,000 | 2,073,000 | $18.76 |
| 12/31/2020 | Applied Therapeutics Inc. | APLT | 160,000 | 38,386 | 3,522,000 | 997,000 | $22.01 |
| 09/30/2020 | Applied Therapeutics Inc. | APLT | 121,614 | -107,110 | 2,525,000 | -5,743,000 | $20.76 |
| 06/30/2020 | Applied Therapeutics Inc. | APLT | 228,724 | -300,750 | 8,268,000 | -9,041,000 | $36.15 |
| 03/31/2020 | Applied Therapeutics Inc. | APLT | 529,474 | 529,474 | 17,309,000 | 17,309,000 | $32.69 |
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