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TIAA CREF INVESTMENT MANAGEMENT LLC
> TSRO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2019 | TESARO, Inc. | TSRO | 0 | -118,382 | 0 | -8,790,000 | |
| 12/31/2018 | TESARO, Inc. | TSRO | 118,382 | -1,254,588 | 8,790,000 | -44,770,000 | $74.25 |
| 09/30/2018 | TESARO, Inc. | TSRO | 1,372,970 | 298,457 | 53,560,000 | 5,776,000 | $39.01 |
| 06/30/2018 | TESARO, Inc. | TSRO | 1,074,513 | 128,027 | 47,784,000 | -6,298,000 | $44.47 |
| 03/31/2018 | TESARO, Inc. | TSRO | 946,486 | 667,697 | 54,082,000 | 30,979,000 | $57.14 |
| 12/31/2017 | TESARO, Inc. | TSRO | 278,789 | -57,145 | 23,103,000 | -20,266,000 | $82.87 |
| 09/30/2017 | TESARO, Inc. | TSRO | 335,934 | -5,674 | 43,369,000 | -4,408,000 | $129.10 |
| 06/30/2017 | TESARO, Inc. | TSRO | 341,608 | -25,911 | 47,777,000 | -8,773,000 | $139.86 |
| 03/31/2017 | TESARO, Inc. | TSRO | 367,519 | 230,353 | 56,550,000 | 38,104,000 | $153.87 |
| 12/31/2016 | TESARO, Inc. | TSRO | 137,166 | 47,187 | 18,446,000 | 9,427,000 | $134.48 |
| 09/30/2016 | TESARO, Inc. | TSRO | 89,979 | -15,250 | 9,019,000 | 4,799,000 | $100.23 |
| 06/30/2016 | TESARO, Inc. | TSRO | 85,908 | 1,524 | 7,221,000 | 3,506,000 | $84.06 |
| 03/31/2016 | TESARO, Inc. | TSRO | 84,384 | -20,845 | 3,715,000 | -505,000 | $44.02 |
| 12/31/2015 | TESARO, Inc. | TSRO | 94,372 | -10,857 | 4,938,000 | 718,000 | $52.32 |
| 09/30/2015 | TESARO, Inc. | TSRO | 105,229 | -7,291 | 4,220,000 | -2,239,000 | $40.10 |
| 06/30/2015 | TESARO, Inc. | TSRO | 112,335 | -185 | 6,604,000 | 145,000 | $58.79 |
| 03/31/2015 | TESARO, Inc. | TSRO | 112,520 | -8,299 | 6,459,000 | 3,207,000 | $57.40 |
| 12/31/2014 | TESARO, Inc. | TSRO | 118,347 | -2,472 | 4,401,000 | 1,149,000 | $37.19 |
| 09/30/2014 | TESARO, Inc. | TSRO | 120,819 | 16,593 | 3,252,000 | 179,000 | $26.92 |
| 06/30/2014 | TESARO, Inc. | TSRO | 134,077 | 29,851 | 4,171,000 | 1,098,000 | $31.11 |
| 03/31/2014 | TESARO, Inc. | TSRO | 104,226 | 20,451 | 3,073,000 | -172,000 | $29.48 |
| 12/31/2013 | TESARO, Inc. | TSRO | 105,546 | 21,771 | 2,981,000 | -264,000 | $28.24 |
| 09/30/2013 | TESARO, Inc. | TSRO | 83,775 | 83,775 | 3,245,000 | 3,245,000 | $38.73 |
| 06/30/2013 | TESARO, Inc. | TSRO | 65,550 | 55,450 | 2,146,000 | 1,975,000 | $32.74 |
| 03/31/2013 | TESARO, Inc. | TSRO | 10,100 | 0 | 221,796 | 50,796 | $21.96 |
| 12/31/2012 | TESARO, Inc. | TSRO | 10,100 | 0 | 171,000 | 27,000 | $16.93 |
| 09/30/2012 | TESARO, Inc. | TSRO | 10,100 | 10,100 | 144,000 | 144,000 | $14.26 |
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