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TWO SIGMA ADVISERS, LP
> CPRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | CATALYST PHARMACEUTICALS, INC. | CPRX | 633,392 | -944,300 | 8,512,788,000 | -17,645,345,000 | $13,440.00 |
| 03/31/2023 | CATALYST PHARMACEUTICALS, INC. | CPRX | 1,577,692 | -233,300 | 26,158,133,000 | -7,526,318,000 | $16,580.00 |
| 12/31/2022 | CATALYST PHARMACEUTICALS, INC. | CPRX | 1,810,992 | 207,500 | 33,684,451,000 | 33,663,878,000 | $18,600.00 |
| 09/30/2022 | CATALYST PHARMACEUTICALS, INC. | CPRX | 1,603,492 | 526,200 | 20,573,000 | 13,021,000 | $12.83 |
| 06/30/2022 | CATALYST PHARMACEUTICALS, INC. | CPRX | 1,077,292 | -156,700 | 7,552,000 | -2,678,000 | $7.01 |
| 03/31/2022 | CATALYST PHARMACEUTICALS, INC. | CPRX | 1,233,992 | 342,800 | 10,230,000 | 4,197,000 | $8.29 |
| 12/31/2021 | CATALYST PHARMACEUTICALS, INC. | CPRX | 891,192 | 485,000 | 6,033,000 | 3,880,000 | $6.77 |
| 09/30/2021 | CATALYST PHARMACEUTICALS, INC. | CPRX | 406,192 | -284,000 | 2,153,000 | -1,816,000 | $5.30 |
| 06/30/2021 | CATALYST PHARMACEUTICALS, INC. | CPRX | 690,192 | -206,400 | 3,969,000 | -164,000 | $5.75 |
| 03/31/2021 | CATALYST PHARMACEUTICALS, INC. | CPRX | 896,592 | 168,200 | 4,133,000 | 1,700,000 | $4.61 |
| 12/31/2020 | CATALYST PHARMACEUTICALS, INC. | CPRX | 728,392 | -5,900 | 2,433,000 | 252,000 | $3.34 |
| 09/30/2020 | CATALYST PHARMACEUTICALS, INC. | CPRX | 734,292 | -360,300 | 2,181,000 | -2,876,000 | $2.97 |
| 06/30/2020 | CATALYST PHARMACEUTICALS, INC. | CPRX | 1,094,592 | 653,400 | 5,057,000 | 3,358,000 | $4.62 |
| 03/31/2020 | CATALYST PHARMACEUTICALS, INC. | CPRX | 441,192 | -15,900 | 1,699,000 | -15,000 | $3.85 |
| 12/31/2019 | CATALYST PHARMACEUTICALS, INC. | CPRX | 457,092 | 444,200 | 1,714,000 | 1,646,000 | $3.75 |
| 09/30/2019 | CATALYST PHARMACEUTICALS, INC. | CPRX | 12,892 | 12,892 | 68,000 | 68,000 | $5.27 |
| 03/31/2019 | CATALYST PHARMACEUTICALS, INC. | CPRX | 0 | -10,000 | 0 | -19,000 | |
| 12/31/2018 | CATALYST PHARMACEUTICALS, INC. | CPRX | 10,000 | -48,200 | 19,000 | -201,000 | $1.90 |
| 09/30/2018 | CATALYST PHARMACEUTICALS, INC. | CPRX | 58,200 | -28,400 | 220,000 | -50,000 | $3.78 |
| 06/30/2018 | CATALYST PHARMACEUTICALS, INC. | CPRX | 86,600 | 20,300 | 270,000 | 112,000 | $3.12 |
| 03/31/2018 | CATALYST PHARMACEUTICALS, INC. | CPRX | 66,300 | -11,792 | 158,000 | -147,000 | $2.38 |
| 12/31/2017 | CATALYST PHARMACEUTICALS, INC. | CPRX | 78,092 | 78,092 | 305,000 | 305,000 | $3.91 |
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