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TWO SIGMA ADVISERS, LP
> MRK
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Merck & Co., Inc. | MRK | 3,900 | -57,400 | 450,021,000 | -6,071,686,000 | $115,390.00 |
| 03/31/2023 | Merck & Co., Inc. | MRK | 61,300 | -471,899 | 6,521,707,000 | -52,636,722,000 | $106,390.00 |
| 12/31/2022 | Merck & Co., Inc. | MRK | 533,199 | -2,119,100 | 59,158,429,000 | 58,930,013,000 | $110,950.00 |
| 09/30/2022 | Merck & Co., Inc. | MRK | 2,652,299 | -1,311,700 | 228,416,000 | -132,982,000 | $86.12 |
| 06/30/2022 | Merck & Co., Inc. | MRK | 3,963,999 | -1,676,300 | 361,398,000 | -101,389,000 | $91.17 |
| 03/31/2022 | Merck & Co., Inc. | MRK | 5,640,299 | 939,700 | 462,787,000 | 102,533,000 | $82.05 |
| 12/31/2021 | Merck & Co., Inc. | MRK | 4,700,599 | -1,579,700 | 360,254,000 | -111,459,000 | $76.64 |
| 09/30/2021 | Merck & Co., Inc. | MRK | 6,280,299 | 801,000 | 471,713,000 | 45,588,000 | $75.11 |
| 06/30/2021 | Merck & Co., Inc. | MRK | 5,479,299 | 1,837,100 | 426,125,000 | 145,348,000 | $77.77 |
| 03/31/2021 | Merck & Co., Inc. | MRK | 3,642,199 | -1,101,400 | 280,777,000 | -107,249,000 | $77.09 |
| 12/31/2020 | Merck & Co., Inc. | MRK | 4,743,599 | 264,200 | 388,026,000 | 16,460,000 | $81.80 |
| 09/30/2020 | Merck & Co., Inc. | MRK | 4,479,399 | -695,500 | 371,566,000 | -28,609,000 | $82.95 |
| 06/30/2020 | Merck & Co., Inc. | MRK | 5,174,899 | 717,100 | 400,175,000 | 57,192,000 | $77.33 |
| 03/31/2020 | Merck & Co., Inc. | MRK | 4,457,799 | -831,000 | 342,983,000 | -138,033,000 | $76.94 |
| 12/31/2019 | Merck & Co., Inc. | MRK | 5,288,799 | 2,841,000 | 481,016,000 | 274,960,000 | $90.95 |
| 09/30/2019 | Merck & Co., Inc. | MRK | 2,447,799 | 803,300 | 206,056,000 | 68,165,000 | $84.18 |
| 06/30/2019 | Merck & Co., Inc. | MRK | 1,644,499 | 1,156,637 | 137,891,000 | 97,316,000 | $83.85 |
| 03/31/2019 | Merck & Co., Inc. | MRK | 487,862 | -1,242,400 | 40,575,000 | -91,634,000 | $83.17 |
| 12/31/2018 | Merck & Co., Inc. | MRK | 1,730,262 | 624,600 | 132,209,000 | 53,773,000 | $76.41 |
| 09/30/2018 | Merck & Co., Inc. | MRK | 1,105,662 | 898,900 | 78,436,000 | 65,886,000 | $70.94 |
| 06/30/2018 | Merck & Co., Inc. | MRK | 206,762 | -823,000 | 12,550,000 | -43,541,000 | $60.70 |
| 03/31/2018 | Merck & Co., Inc. | MRK | 1,029,762 | -399,281 | 56,091,000 | -24,321,000 | $54.47 |
| 12/31/2017 | Merck & Co., Inc. | MRK | 1,429,043 | -86,207 | 80,412,000 | -16,609,000 | $56.27 |
| 09/30/2017 | Merck & Co., Inc. | MRK | 1,515,250 | 518,349 | 97,021,000 | 33,130,000 | $64.03 |
| 06/30/2017 | Merck & Co., Inc. | MRK | 996,901 | -1,303,161 | 63,891,000 | -82,255,000 | $64.09 |
| 03/31/2017 | Merck & Co., Inc. | MRK | 2,300,062 | 1,006,893 | 146,146,000 | 70,017,000 | $63.54 |
| 12/31/2016 | Merck & Co., Inc. | MRK | 1,293,169 | 630,304 | 76,129,000 | 34,760,000 | $58.87 |
| 09/30/2016 | Merck & Co., Inc. | MRK | 662,865 | 275,100 | 41,369,000 | 19,030,000 | $62.41 |
| 06/30/2016 | Merck & Co., Inc. | MRK | 387,765 | 387,765 | 22,339,000 | 22,339,000 | $57.61 |
| 03/31/2016 | Merck & Co., Inc. | MRK | 138,665 | 138,665 | 7,337,000 | 7,337,000 | $52.91 |
| 12/31/2015 | Merck & Co., Inc. | MRK | 1,493,524 | 293,972 | 78,888,000 | 9,938,000 | $52.82 |
| 09/30/2015 | Merck & Co., Inc. | MRK | 1,729,234 | 1,729,234 | 85,407,000 | 85,407,000 | $49.39 |
| 06/30/2015 | Merck & Co., Inc. | MRK | 167,833 | -1,031,719 | 9,555,000 | -59,395,000 | $56.93 |
| 03/31/2015 | Merck & Co., Inc. | MRK | 1,286,452 | 1,286,452 | 73,945,000 | 73,945,000 | $57.48 |
| 12/31/2014 | Merck & Co., Inc. | MRK | 952,322 | 514,870 | 54,082,000 | 28,148,000 | $56.79 |
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