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NEEDHAM INVESTMENT MANAGEMENT LLC
> GTHX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2022 | G1 Therapeutics, Inc. | GTHX | 184,000 | 50,000 | 999,120,000 | 997,447,000 | $5,430.00 |
| 09/30/2022 | G1 Therapeutics, Inc. | GTHX | 134,000 | 0 | 1,673,000 | 1,011,000 | $12.49 |
| 06/30/2022 | G1 Therapeutics, Inc. | GTHX | 134,000 | -26,000 | 662,000 | -554,000 | $4.94 |
| 03/31/2022 | G1 Therapeutics, Inc. | GTHX | 160,000 | 45,000 | 1,216,000 | 42,000 | $7.60 |
| 12/31/2021 | G1 Therapeutics, Inc. | GTHX | 115,000 | 87,500 | 1,174,000 | 571,000 | $10.21 |
| 06/30/2021 | G1 Therapeutics, Inc. | GTHX | 27,500 | 7,500 | 603,000 | 122,000 | $21.93 |
| 03/31/2021 | G1 Therapeutics, Inc. | GTHX | 20,000 | 2,000 | 481,000 | 157,000 | $24.05 |
| 12/31/2020 | G1 Therapeutics, Inc. | GTHX | 18,000 | 18,000 | 324,000 | 324,000 | $18.00 |
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