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PICTET ASSET MANAGEMENT LTD
> LXRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 0 | -994,476 | 0 | -3,401,000 | |
| 12/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 994,476 | -57,900 | 3,401,000 | 1,886,000 | $3.42 |
| 09/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,052,376 | -51,900 | 1,515,000 | -688,000 | $1.44 |
| 06/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,104,276 | -97,800 | 2,203,000 | -141,000 | $1.99 |
| 03/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,202,076 | 502,700 | 2,344,000 | -558,000 | $1.95 |
| 12/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 699,376 | -30,500 | 2,902,000 | 705,000 | $4.15 |
| 09/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 729,876 | 64,100 | 2,197,000 | -1,991,000 | $3.01 |
| 06/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 665,776 | 78,926 | 4,188,000 | 925,000 | $6.29 |
| 03/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 586,850 | 175,400 | 3,263,000 | 531,000 | $5.56 |
| 12/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 411,450 | 142,200 | 2,732,000 | -141,000 | $6.64 |
| 09/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 269,250 | -24,400 | 2,873,000 | -651,000 | $10.67 |
| 06/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 293,650 | -110,000 | 3,524,000 | 65,000 | $12.00 |
| 03/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 403,650 | 143,100 | 3,459,000 | 885,000 | $8.57 |
| 12/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 260,550 | 185,300 | 2,574,000 | 1,649,000 | $9.88 |
| 09/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 75,250 | 13,700 | 925,000 | 42,000 | $12.29 |
| 03/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 61,550 | 6,800 | 883,000 | 126,000 | $14.35 |
| 12/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 54,750 | 54,750 | 757,000 | 757,000 | $13.83 |
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