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CITADEL ADVISORS LLC
> SPRO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Spero Therapeutics, Inc. | SPRO | 14,956 | 14,956 | 21,686,000 | 21,686,000 | $1,449.99 |
| 09/30/2022 | Spero Therapeutics, Inc. | SPRO | 0 | -108,351 | 0 | -80,000 | |
| 06/30/2022 | Spero Therapeutics, Inc. | SPRO | 108,351 | 97,554 | 80,000 | -14,000 | $0.74 |
| 03/31/2022 | Spero Therapeutics, Inc. | SPRO | 10,797 | 10,797 | 94,000 | 94,000 | $8.71 |
| 09/30/2021 | Spero Therapeutics, Inc. | SPRO | 0 | -11,812 | 0 | -165,000 | |
| 06/30/2021 | Spero Therapeutics, Inc. | SPRO | 11,812 | -8,268 | 165,000 | -131,000 | $13.97 |
| 03/31/2021 | Spero Therapeutics, Inc. | SPRO | 20,080 | -12,558 | 296,000 | -337,000 | $14.74 |
| 12/31/2020 | Spero Therapeutics, Inc. | SPRO | 32,638 | 11,328 | 633,000 | 395,000 | $19.39 |
| 09/30/2020 | Spero Therapeutics, Inc. | SPRO | 21,310 | 21,310 | 238,000 | 238,000 | $11.17 |
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