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CITADEL ADVISORS LLC
> HRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 435,991 | -1,057,862 | 505,750,000 | -3,228,883,000 | $1,160.00 |
| 12/31/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,493,853 | 441,157 | 3,734,633,000 | 3,730,191,000 | $2,500.00 |
| 09/30/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,052,696 | 956,712 | 4,442,000 | 4,174,000 | $4.22 |
| 06/30/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 95,984 | -115,588 | 268,000 | -942,000 | $2.79 |
| 03/31/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 211,572 | -1,481,347 | 1,210,000 | -14,246,000 | $5.72 |
| 12/31/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,692,919 | 1,552,390 | 15,456,000 | 13,954,000 | $9.13 |
| 09/30/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 140,529 | 78,273 | 1,502,000 | 536,000 | $10.69 |
| 06/30/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 62,256 | -440,222 | 966,000 | -7,179,000 | $15.52 |
| 03/31/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 502,478 | -158,502 | 8,145,000 | -5,844,000 | $16.21 |
| 12/31/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 660,980 | 539,643 | 13,989,000 | 12,191,000 | $21.16 |
| 09/30/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 121,337 | -286,337 | 1,798,000 | -4,198,000 | $14.82 |
| 06/30/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 407,674 | -1,101,232 | 5,996,000 | -11,719,000 | $14.71 |
| 03/31/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,508,906 | -329,744 | 17,715,000 | -25,493,000 | $11.74 |
| 12/31/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,838,650 | 196,650 | 43,208,000 | 12,831,000 | $23.50 |
| 09/30/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,642,000 | 324,462 | 30,377,000 | 5,884,000 | $18.50 |
| 06/30/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,317,538 | 367,914 | 24,493,000 | 1,284,000 | $18.59 |
| 03/31/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 949,624 | -1,692,479 | 23,209,000 | -45,327,000 | $24.44 |
| 12/31/2018 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 2,642,103 | 756,523 | 68,536,000 | 8,858,000 | $25.94 |
| 09/30/2018 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,885,580 | 625,420 | 59,678,000 | 10,721,000 | $31.65 |
| 06/30/2018 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,260,160 | 329,647 | 48,957,000 | 23,275,000 | $38.85 |
| 03/31/2018 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 930,513 | -659,351 | 25,682,000 | -3,095,000 | $27.60 |
| 12/31/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,589,864 | 1,404,870 | 28,777,000 | 25,789,000 | $18.10 |
| 09/30/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 184,994 | -1,122,782 | 2,988,000 | -15,125,000 | $16.15 |
| 06/30/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,307,776 | 24,097 | 18,113,000 | -1,142,000 | $13.85 |
| 03/31/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,283,679 | 1,234,557 | 19,255,000 | 18,612,000 | $15.00 |
| 12/31/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 49,122 | 49,122 | 643,000 | 643,000 | $13.09 |
| 09/30/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 0 | -213,517 | 0 | -3,854,000 | |
| 06/30/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 213,517 | 185,564 | 3,854,000 | 3,323,000 | $18.05 |
| 03/31/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 27,953 | -301,032 | 531,000 | -8,253,000 | $19.00 |
| 12/31/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 328,985 | 328,985 | 8,784,000 | 8,784,000 | $26.70 |
| 09/30/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 0 | -4,262 | 0 | -133,000 | |
| 06/30/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 4,262 | -11,441 | 133,000 | -95,000 | $31.21 |
| 03/31/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 15,703 | 2,649 | 228,000 | 97,000 | $14.52 |
| 12/31/2014 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 13,054 | 13,054 | 131,000 | 131,000 | $10.04 |
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