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BROWN JAMES E
> DRRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2004 | DURECT CORP | DRRX | 2,927,450 | 92,150 | 9,602,036 | 4,583,555 | $3.28 |
| 01/31/2003 | DURECT CORP | DRRX | 2,835,300 | 45,300 | 5,018,481 | -19,812,519 | $1.77 |
| 01/31/2002 | DURECT CORP | DRRX | 2,790,000 | -30,000 | 24,831,000 | 522,600 | $8.90 |
| 01/31/2001 | DURECT CORP | DRRX | 2,820,000 | 2,820,000 | 24,308,400 | 24,308,400 | $8.62 |
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