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MORGAN STANLEY
> SPRB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 2,131 | -1,208 | 4,582,000 | 918,000 | $2,150.16 |
| 12/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 3,339 | -19,835 | 3,664,000 | 3,633,000 | $1,097.33 |
| 09/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 23,174 | -37,486 | 31,000 | -75,000 | $1.34 |
| 06/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 60,660 | 49,239 | 106,000 | 84,000 | $1.75 |
| 03/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 11,421 | -970 | 22,000 | -33,000 | $1.93 |
| 12/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 12,391 | -63,520 | 55,000 | -401,000 | $4.44 |
| 09/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 75,911 | -46,679 | 456,000 | -919,000 | $6.01 |
| 06/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 122,590 | 88,298 | 1,375,000 | 806,000 | $11.22 |
| 03/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 34,292 | 28,963 | 569,000 | 440,000 | $16.59 |
| 12/31/2020 | SPRUCE BIOSCIENCES, INC. | SPRB | 5,329 | 5,329 | 129,000 | 129,000 | $24.21 |
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