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MORGAN STANLEY
> SPRO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Spero Therapeutics, Inc. | SPRO | 9,530 | -7,547 | 13,819,000 | -15,724,000 | $1,450.05 |
| 12/31/2022 | Spero Therapeutics, Inc. | SPRO | 17,077 | -2,177 | 29,543,000 | 29,505,000 | $1,729.99 |
| 09/30/2022 | Spero Therapeutics, Inc. | SPRO | 19,254 | -175,177 | 38,000 | -106,000 | $1.97 |
| 06/30/2022 | Spero Therapeutics, Inc. | SPRO | 194,431 | 121,435 | 144,000 | -491,000 | $0.74 |
| 03/31/2022 | Spero Therapeutics, Inc. | SPRO | 72,996 | 22,511 | 635,000 | -173,000 | $8.70 |
| 12/31/2021 | Spero Therapeutics, Inc. | SPRO | 50,485 | -6,016 | 808,000 | -233,000 | $16.00 |
| 09/30/2021 | Spero Therapeutics, Inc. | SPRO | 56,501 | -13,271 | 1,041,000 | 67,000 | $18.42 |
| 06/30/2021 | Spero Therapeutics, Inc. | SPRO | 69,772 | -119,177 | 974,000 | -1,807,000 | $13.96 |
| 03/31/2021 | Spero Therapeutics, Inc. | SPRO | 188,949 | -82,309 | 2,781,000 | -2,478,000 | $14.72 |
| 12/31/2020 | Spero Therapeutics, Inc. | SPRO | 271,258 | 248,326 | 5,259,000 | 5,003,000 | $19.39 |
| 09/30/2020 | Spero Therapeutics, Inc. | SPRO | 22,932 | -2,838 | 256,000 | -92,000 | $11.16 |
| 06/30/2020 | Spero Therapeutics, Inc. | SPRO | 25,770 | 24,374 | 348,000 | 337,000 | $13.50 |
| 03/31/2020 | Spero Therapeutics, Inc. | SPRO | 1,396 | -15,158 | 11,000 | -148,000 | $7.88 |
| 12/31/2019 | Spero Therapeutics, Inc. | SPRO | 16,554 | 12,345 | 159,000 | 114,000 | $9.60 |
| 09/30/2019 | Spero Therapeutics, Inc. | SPRO | 4,209 | 2,717 | 45,000 | 28,000 | $10.69 |
| 06/30/2019 | Spero Therapeutics, Inc. | SPRO | 1,492 | -1,715 | 17,000 | -24,000 | $11.39 |
| 03/31/2019 | Spero Therapeutics, Inc. | SPRO | 3,207 | -23,592 | 41,000 | -123,000 | $12.78 |
| 12/31/2018 | Spero Therapeutics, Inc. | SPRO | 26,799 | 12,775 | 164,000 | 17,000 | $6.12 |
| 09/30/2018 | Spero Therapeutics, Inc. | SPRO | 14,024 | -570 | 147,000 | -67,000 | $10.48 |
| 06/30/2018 | Spero Therapeutics, Inc. | SPRO | 14,594 | 3,564 | 214,000 | 57,000 | $14.66 |
| 03/31/2018 | Spero Therapeutics, Inc. | SPRO | 11,030 | 477 | 157,000 | 33,000 | $14.23 |
| 12/31/2017 | Spero Therapeutics, Inc. | SPRO | 10,553 | 10,553 | 124,000 | 124,000 | $11.75 |
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