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JPMORGAN CHASE & CO
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 5,955,525 | -405,233 | 2,095,808,937,000 | 91,724,429,000 | $351,910.02 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,360,758 | 1,501,071 | 2,004,084,508,000 | 2,002,677,434,000 | $315,070.08 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,859,687 | -377,855 | 1,407,074,000 | -68,813,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 5,237,542 | 424,873 | 1,475,887,000 | 219,926,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,812,669 | 348,338 | 1,255,961,000 | 275,593,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,464,331 | 252,599 | 980,368,000 | 216,401,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,211,732 | -226,331 | 763,967,000 | -130,879,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,438,063 | 1,231,763 | 894,846,000 | 205,846,000 | $201.63 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,206,300 | 618,276 | 689,000,000 | 77,347,000 | $214.89 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,588,024 | 348,214 | 611,653,000 | 6,210,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,239,810 | 126,724 | 605,443,000 | -8,006,000 | $270.31 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,113,086 | -81,689 | 613,449,000 | 91,202,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,194,775 | -390,614 | 522,247,000 | -43,824,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,585,389 | -788,425 | 566,071,000 | -5,519,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,373,814 | -959,889 | 571,590,000 | -202,323,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,333,703 | -2,449,932 | 773,913,000 | -473,935,000 | $178.58 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,783,635 | -403,886 | 1,247,848,000 | 56,805,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,187,521 | 70,305 | 1,191,043,000 | -180,726,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,117,216 | 355,139 | 1,371,769,000 | 222,487,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,762,077 | -1,222,383 | 1,149,282,000 | -152,028,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,984,460 | -1,413,492 | 1,301,310,000 | -107,066,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 9,397,952 | 75,505 | 1,408,376,000 | 13,549,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 9,322,447 | 939,894 | 1,394,827,000 | 314,567,000 | $149.62 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 8,382,553 | -978,823 | 1,080,260,000 | 56,595,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 9,361,376 | -1,235,572 | 1,023,665,000 | 242,742,000 | $109.35 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 10,596,948 | -430,141 | 780,923,000 | -181,189,000 | $73.69 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 11,027,089 | 11,027,089 | 962,112,000 | 962,112,000 | $87.25 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 12,173,439 | 12,173,439 | 1,047,161,000 | 1,047,161,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 11,688,327 | 11,688,327 | 929,105,000 | 929,105,000 | $79.49 |
| 03/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -10,426,234 | 0 | -1,238,635,000 | |
| 12/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 10,426,234 | 10,426,234 | 1,238,635,000 | 1,238,635,000 | $118.80 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 10,591,405 | 10,591,405 | 1,189,520,000 | 1,189,520,000 | $112.31 |
| 06/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 9,635,998 | 9,635,998 | 912,335,000 | 912,335,000 | $94.68 |
| 03/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,606,689 | 7,606,689 | 537,946,000 | 537,946,000 | $70.72 |
| 12/31/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 9,180,258 | 9,180,258 | 682,094,000 | 682,094,000 | $74.30 |
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