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Bank of New York Mellon Corp
> SPRB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 91,455 | -622 | 196,628,000 | -6,862,000 | $2,150.00 |
| 03/31/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 92,077 | 0 | 203,490,000 | 102,445,000 | $2,210.00 |
| 12/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 92,077 | 92,077 | 101,045,000 | 101,045,000 | $1,097.40 |
| 09/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 0 | -92,764 | 0 | -161,000 | |
| 06/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 92,764 | -23,737 | 161,000 | -73,000 | $1.74 |
| 03/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 116,501 | 88,608 | 234,000 | 110,000 | $2.01 |
| 12/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 27,893 | 445 | 124,000 | -41,000 | $4.45 |
| 09/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 27,448 | 1,882 | 165,000 | -121,000 | $6.01 |
| 06/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 25,566 | 12,074 | 286,000 | -42,000 | $11.19 |
| 03/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 0 | -13,492 | 0 | -328,000 | |
| 12/31/2020 | SPRUCE BIOSCIENCES, INC. | SPRB | 13,492 | 13,492 | 328,000 | 328,000 | $24.31 |
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