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PICTET ASSET MANAGEMENT SA
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,075,836 | -100,477 | 378,597,447,000 | 7,976,510,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,176,313 | 393,530 | 370,620,937,000 | 370,394,290,000 | $315,070.00 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 782,783 | 59,632 | 226,647,000 | 22,870,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 723,151 | -184,515 | 203,777,000 | -33,097,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 907,666 | -304,653 | 236,874,000 | -29,351,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,212,319 | 147,497 | 266,225,000 | 73,077,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,064,822 | 1,064,822 | 193,148,000 | 193,148,000 | $181.39 |
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