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PICTET ASSET MANAGEMENT SA
> AGIO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 882,402 | 186,326 | 24,989,625,000 | 9,000,759,000 | $28,320.00 |
| 03/31/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 696,076 | 500,855 | 15,988,866,000 | 15,983,345,000 | $22,970.00 |
| 09/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 195,221 | 29,249 | 5,521,000 | 1,841,000 | $28.28 |
| 06/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 165,972 | 41,686 | 3,680,000 | 62,000 | $22.17 |
| 03/31/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 124,286 | 14,476 | 3,618,000 | 9,000 | $29.11 |
| 12/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 109,810 | 4,878 | 3,609,000 | -1,234,000 | $32.87 |
| 09/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 104,932 | 104,932 | 4,843,000 | 4,843,000 | $46.15 |
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