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MILLENNIUM MANAGEMENT LLC
> DNLI
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Denali Therapeutics Inc. | DNLI | 478,186 | 181,093 | 14,111,269,000 | 14,103,007,000 | $29,510.00 |
| 12/31/2022 | Denali Therapeutics Inc. | DNLI | 297,093 | -199,091 | 8,262,000 | -6,966,000 | $27.81 |
| 09/30/2022 | Denali Therapeutics Inc. | DNLI | 496,184 | -149,152 | 15,228,000 | -3,764,000 | $30.69 |
| 06/30/2022 | Denali Therapeutics Inc. | DNLI | 645,336 | 645,336 | 18,992,000 | 18,992,000 | $29.43 |
| 03/31/2022 | Denali Therapeutics Inc. | DNLI | 0 | -18,360 | 0 | -819,000 | |
| 12/31/2021 | Denali Therapeutics Inc. | DNLI | 18,360 | -23,482 | 819,000 | -1,292,000 | $44.61 |
| 09/30/2021 | Denali Therapeutics Inc. | DNLI | 41,842 | 22,399 | 2,111,000 | 586,000 | $50.45 |
| 06/30/2021 | Denali Therapeutics Inc. | DNLI | 19,443 | 4,731 | 1,525,000 | 685,000 | $78.43 |
| 03/31/2021 | Denali Therapeutics Inc. | DNLI | 14,712 | 8,898 | 840,000 | 353,000 | $57.10 |
| 12/31/2020 | Denali Therapeutics Inc. | DNLI | 5,814 | -16,495 | 487,000 | -52,000 | $83.76 |
| 06/30/2020 | Denali Therapeutics Inc. | DNLI | 22,309 | 22,309 | 539,000 | 539,000 | $24.16 |
| 12/31/2019 | Denali Therapeutics Inc. | DNLI | 0 | -101,659 | 0 | -1,557,000 | |
| 09/30/2019 | Denali Therapeutics Inc. | DNLI | 101,659 | 101,659 | 1,557,000 | 1,557,000 | $15.32 |
| 06/30/2019 | Denali Therapeutics Inc. | DNLI | 0 | -34,451 | 0 | -800,000 | |
| 03/31/2019 | Denali Therapeutics Inc. | DNLI | 34,451 | 34,451 | 800,000 | 800,000 | $23.22 |
| 09/30/2018 | Denali Therapeutics Inc. | DNLI | 0 | -171,979 | 0 | -2,623,000 | |
| 06/30/2018 | Denali Therapeutics Inc. | DNLI | 171,979 | 171,979 | 2,623,000 | 2,623,000 | $15.25 |
| 03/31/2018 | Denali Therapeutics Inc. | DNLI | 0 | -94,316 | 0 | -1,475,000 | |
| 12/31/2017 | Denali Therapeutics Inc. | DNLI | 94,316 | 94,316 | 1,475,000 | 1,475,000 | $15.64 |
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