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AMERICAN CENTURY COMPANIES INC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,001,430 | -149,472 | 352,413,232,000 | -9,871,913,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,150,902 | -109,195 | 362,285,145,000 | 361,920,296,000 | $314,783.66 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,260,097 | 80,563 | 364,849,000 | 32,468,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,179,534 | 78,659 | 332,381,000 | 45,086,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,100,875 | 476,422 | 287,295,000 | 150,165,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 624,453 | -145,053 | 137,130,000 | -2,451,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 769,506 | -130,754 | 139,581,000 | -41,939,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 900,260 | -31,572 | 181,520,000 | -38,710,000 | $201.63 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 931,832 | -96,336 | 220,230,000 | -59,555,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,028,168 | 214,855 | 279,785,000 | 43,672,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 813,313 | -285,928 | 236,113,000 | -25,452,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,099,241 | -26,623 | 261,565,000 | 15,057,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,125,864 | 135,987 | 246,508,000 | 78,803,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 989,877 | 68,701 | 167,705,000 | -1,220,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 921,176 | 11,067 | 168,925,000 | 1,510,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 910,109 | -49,448 | 167,415,000 | 8,407,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 959,557 | -188,868 | 159,008,000 | -62,339,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,148,425 | 22,997 | 221,347,000 | 30,069,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,125,428 | 879,411 | 191,278,000 | 151,182,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 246,017 | 67,911 | 40,096,000 | 13,405,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 178,106 | 14,560 | 26,691,000 | 1,825,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 163,546 | -60,807 | 24,866,000 | -4,046,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 224,353 | 63,854 | 28,912,000 | 11,361,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 160,499 | -129,475 | 17,551,000 | -3,811,000 | $109.35 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 289,974 | -442,629 | 21,362,000 | -42,528,000 | $73.67 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 732,603 | -585,251 | 63,890,000 | -49,472,000 | $87.21 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,317,854 | 936,494 | 113,362,000 | 84,447,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,756,022 | 245,477 | 139,586,000 | -50,486,000 | $79.49 |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,510,545 | 300,457 | 190,072,000 | 64,053,000 | $125.83 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,210,088 | 582,852 | 126,019,000 | 48,568,000 | $104.14 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 627,236 | -40,940 | 77,451,000 | -1,374,000 | $123.48 |
| 03/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 668,176 | 550,634 | 78,825,000 | 64,861,000 | $117.97 |
| 12/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 117,542 | -29,858 | 13,964,000 | 8,000 | $118.80 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 117,495 | -29,905 | 13,196,000 | -760,000 | $112.31 |
| 06/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 147,400 | -233,960 | 13,956,000 | -14,959,000 | $94.68 |
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