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AMERIPRISE FINANCIAL INC
> AGIO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 325,221 | 19,507 | 9,210,259,000 | 2,188,009,000 | $28,320.00 |
| 03/31/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 305,714 | 67,705 | 7,022,250,000 | 338,250,000 | $22,970.00 |
| 12/31/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 238,009 | 77,932 | 6,684,000,000 | 6,679,473,000 | $28,082.97 |
| 09/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 160,077 | 160,077 | 4,527,000 | 4,527,000 | $28.28 |
| 12/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 0 | -55,185 | 0 | -2,547,000 | |
| 09/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 55,185 | -43,486 | 2,547,000 | -2,891,000 | $46.15 |
| 06/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 98,671 | 44,146 | 5,438,000 | 2,622,000 | $55.11 |
| 03/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 54,525 | 8,013 | 2,816,000 | 801,000 | $51.65 |
| 12/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 46,512 | -19,917 | 2,015,000 | -310,000 | $43.32 |
| 09/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 66,429 | 62,087 | 2,325,000 | 2,093,000 | $35.00 |
| 06/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 4,342 | -118,068 | 232,000 | -4,112,000 | $53.43 |
| 03/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 122,410 | -964,438 | 4,344,000 | -47,554,000 | $35.49 |
| 12/31/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,086,848 | -209,776 | 51,898,000 | 9,887,000 | $47.75 |
| 09/30/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,296,624 | 198,622 | 42,011,000 | -12,757,000 | $32.40 |
| 06/30/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,098,002 | 464,123 | 54,768,000 | 12,019,000 | $49.88 |
| 03/31/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 633,879 | -13,706 | 42,749,000 | 12,889,000 | $67.44 |
| 12/31/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 647,585 | 153,944 | 29,860,000 | -8,209,000 | $46.11 |
| 09/30/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 493,641 | 172,091 | 38,069,000 | 10,984,000 | $77.12 |
| 06/30/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 321,550 | -176,871 | 27,085,000 | -13,675,000 | $84.23 |
| 03/31/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 498,421 | 443,934 | 40,760,000 | 37,638,000 | $81.78 |
| 12/31/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 54,487 | -3,017 | 3,122,000 | -716,000 | $57.30 |
| 09/30/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 57,504 | 7,510 | 3,838,000 | 1,266,000 | $66.74 |
| 06/30/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 49,994 | 8,965 | 2,572,000 | 175,000 | $51.45 |
| 03/31/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 41,029 | 3,215 | 2,397,000 | 819,000 | $58.42 |
| 12/31/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 37,814 | 7,157 | 1,578,000 | -41,000 | $41.73 |
| 09/30/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 30,657 | 30,657 | 1,619,000 | 1,619,000 | $52.81 |
| 06/30/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 22,029 | 2,983 | 923,000 | 150,000 | $41.90 |
| 03/31/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 19,046 | 2,771 | 773,000 | -284,000 | $40.59 |
| 12/31/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 16,275 | 4,614 | 1,057,000 | -249,000 | $64.95 |
| 09/30/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 9,958 | -1,703 | 703,000 | -603,000 | $70.60 |
| 06/30/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 10,738 | -923 | 1,193,000 | -113,000 | $111.10 |
| 03/31/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 6,123 | -5,538 | 578,000 | -728,000 | $94.40 |
| 12/31/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 11,661 | -25,747 | 1,306,000 | -408,000 | $112.00 |
| 09/30/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 23,520 | -13,888 | 1,443,000 | -271,000 | $61.35 |
| 06/30/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 37,408 | 37,408 | 1,714,000 | 1,714,000 | $45.82 |
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