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Jefferies Group LLC
> DRRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2022 | DURECT CORP | DRRX | 275,653 | 0 | 159,000 | 27,000 | $0.58 |
| 06/30/2022 | DURECT CORP | DRRX | 275,653 | -750,000 | 132,000 | -555,000 | $0.48 |
| 03/31/2022 | DURECT CORP | DRRX | 1,025,653 | 108,400 | 687,000 | -182,000 | $0.67 |
| 12/31/2021 | DURECT CORP | DRRX | 917,253 | 66,600 | 869,000 | -220,000 | $0.95 |
| 09/30/2021 | DURECT CORP | DRRX | 850,653 | 0 | 1,089,000 | -298,000 | $1.28 |
| 06/30/2021 | DURECT CORP | DRRX | 850,653 | -175,000 | 1,387,000 | -644,000 | $1.63 |
| 03/31/2021 | DURECT CORP | DRRX | 1,025,653 | 0 | 2,031,000 | -92,000 | $1.98 |
| 12/31/2020 | DURECT CORP | DRRX | 1,025,653 | 0 | 2,123,000 | 369,000 | $2.07 |
| 09/30/2020 | DURECT CORP | DRRX | 1,025,653 | 0 | 1,754,000 | -626,000 | $1.71 |
| 06/30/2020 | DURECT CORP | DRRX | 1,025,653 | 75,933 | 2,380,000 | 908,000 | $2.32 |
| 03/31/2020 | DURECT CORP | DRRX | 949,720 | 949,720 | 1,472,000 | 1,472,000 | $1.55 |
| 12/31/2018 | DURECT CORP | DRRX | 0 | -19,200 | 0 | -21,000 | |
| 09/30/2018 | DURECT CORP | DRRX | 19,200 | 19,200 | 21,000 | 21,000 | $1.09 |
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