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UBS ASSET MANAGEMENT AMERICAS INC
> LXRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | LEXICON PHARMACEUTICALS, INC. | LXRX | 137,735 | 18,689 | 334,697,000 | 334,469,622 | $2,430.01 |
| 12/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 119,046 | 0 | 227,378 | -285,483,622 | $1.91 |
| 09/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 119,046 | -56,904 | 285,711,000 | -41,556,000 | $2,400.01 |
| 06/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 175,950 | 92,076 | 327,267,000 | 327,091,703 | $1,860.00 |
| 03/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 83,874 | 0 | 175,297 | -155,167 | $2.09 |
| 12/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 83,874 | 0 | 330,464 | -403,104,536 | $3.94 |
| 09/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 83,874 | 7,499 | 403,435,000 | 52,874,000 | $4,810.01 |
| 06/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 76,375 | 76,375 | 350,561,000 | 350,561,000 | $4,590.00 |
| 06/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 0 | -48,341 | 0 | -94,265 | |
| 03/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 48,341 | -1,063,307 | 94,265 | -4,519,075 | $1.95 |
| 12/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,111,648 | -7,552 | 4,613,340 | 1,244,548 | $4.15 |
| 09/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,119,200 | 4,669 | 3,368,792 | -3,641,608 | $3.01 |
| 06/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,114,531 | 0 | 7,010,400 | 813,607 | $6.29 |
| 03/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,114,531 | -1,827,892 | 6,196,793 | -13,340,895 | $5.56 |
| 12/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 4,244,391 | 440,363 | 28,182,756 | -12,406,221 | $6.64 |
| 09/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 3,804,028 | -170,868 | 40,588,977 | -7,109,775 | $10.67 |
| 06/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 3,974,896 | -38,377 | 47,698,752 | 13,305,002 | $12.00 |
| 03/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 4,013,273 | -147,199 | 34,393,750 | -6,711,715 | $8.57 |
| 12/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 5,595,669 | 2,018,119 | 55,285,210 | 11,317,122 | $9.88 |
| 09/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 3,577,550 | -235,952 | 43,968,088 | -18,764,021 | $12.29 |
| 06/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 3,813,502 | -275,917 | 62,732,109 | 4,089,840 | $16.45 |
| 03/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 4,089,419 | 3,663,015 | 58,642,269 | 52,745,269 | $14.34 |
| 12/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 426,404 | -4,364,577 | 5,897,000 | -80,676,000 | $13.83 |
| 09/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 4,790,981 | 4,790,981 | 86,573,000 | 86,573,000 | $18.07 |
| 06/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 6,570,712 | 6,570,712 | 94,289,000 | 94,289,000 | $14.35 |
| 03/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 7,221,718 | -1,230,797 | 86,299,000 | -26,205,000 | $11.95 |
| 12/31/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 8,452,515 | 8,452,515 | 112,504,000 | 112,504,000 | $13.31 |
| 09/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 8,389,120 | 8,389,120 | 90,099,000 | 90,099,000 | $10.74 |
| 06/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 6,473,674 | 6,473,674 | 52,113,000 | 52,113,000 | $8.05 |
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