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RENAISSANCE TECHNOLOGIES LLC
> AVGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2009 | AVIGEN INC \DE | AVGN | 1,024,600 | 3,700 | 1,271,000 | -250,000 | $1.24 |
| 09/30/2009 | AVIGEN INC \DE | AVGN | 1,020,900 | 71,300 | 1,521,000 | 268,000 | $1.49 |
| 06/30/2009 | AVIGEN INC \DE | AVGN | 949,600 | 93,000 | 1,253,000 | 208,000 | $1.32 |
| 03/31/2009 | AVIGEN INC \DE | AVGN | 856,600 | 79,700 | 1,045,000 | 455,000 | $1.22 |
| 12/31/2008 | AVIGEN INC \DE | AVGN | 776,900 | 776,900 | 590,000 | 590,000 | $0.76 |
| 09/30/2008 | AVIGEN INC \DE | AVGN | 716,200 | 34,300 | 2,865,000 | 894,000 | $4.00 |
| 06/30/2008 | AVIGEN INC \DE | AVGN | 681,900 | 15,100 | 1,971,000 | 111,000 | $2.89 |
| 03/31/2008 | AVIGEN INC \DE | AVGN | 666,800 | 11,900 | 1,860,000 | -923,000 | $2.79 |
| 12/31/2007 | AVIGEN INC \DE | AVGN | 654,900 | 33,700 | 2,783,000 | -571,000 | $4.25 |
| 09/30/2007 | AVIGEN INC \DE | AVGN | 621,200 | 44,100 | 3,354,000 | -195,000 | $5.40 |
| 06/30/2007 | AVIGEN INC \DE | AVGN | 577,100 | 53,500 | 3,549,000 | 151,000 | $6.15 |
| 03/31/2007 | AVIGEN INC \DE | AVGN | 523,600 | 96,400 | 3,398,000 | 1,142,000 | $6.49 |
| 12/31/2006 | AVIGEN INC \DE | AVGN | 427,200 | 427,200 | 2,256,000 | 2,256,000 | $5.28 |
| 09/30/2006 | AVIGEN INC \DE | AVGN | 337,100 | 55,900 | 1,743,000 | 286,000 | $5.17 |
| 06/30/2006 | AVIGEN INC \DE | AVGN | 281,200 | 152,600 | 1,457,000 | 792,000 | $5.18 |
| 03/31/2006 | AVIGEN INC \DE | AVGN | 128,600 | 100,500 | 665,000 | 580,000 | $5.17 |
| 12/31/2005 | AVIGEN INC \DE | AVGN | 28,100 | 28,100 | 85,000 | 85,000 | $3.02 |
| 09/30/2004 | AVIGEN INC \DE | AVGN | 0 | -77,610 | 0 | -262,000 | |
| 06/30/2004 | AVIGEN INC \DE | AVGN | 77,610 | 77,610 | 262,000 | 262,000 | $3.38 |
| 06/30/2001 | AVIGEN INC \DE | AVGN | 0 | -27,900 | 0 | -340,000 | |
| 03/31/2001 | AVIGEN INC \DE | AVGN | 27,900 | -23,042 | 340,000 | -717,000 | $12.19 |
| 12/31/2000 | AVIGEN INC \DE | AVGN | 50,942 | 50,942 | 1,057,000 | 1,057,000 | $20.75 |
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