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STATE STREET CORP
> SPRB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 58,793 | -34,307 | 126,405,000 | 23,995,000 | $2,150.00 |
| 12/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 93,100 | 0 | 102,410,000 | 102,282,000 | $1,100.00 |
| 09/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 93,100 | 0 | 128,000 | -34,000 | $1.37 |
| 06/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 93,100 | -112,359 | 162,000 | -251,000 | $1.74 |
| 03/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 205,459 | 78,490 | 413,000 | -153,000 | $2.01 |
| 12/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 126,969 | -848 | 566,000 | -202,000 | $4.46 |
| 09/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 127,817 | 2,899 | 768,000 | -632,000 | $6.01 |
| 06/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 124,918 | 30,169 | 1,400,000 | -173,000 | $11.21 |
| 03/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 94,749 | 6,771 | 1,573,000 | -566,000 | $16.60 |
| 12/31/2020 | SPRUCE BIOSCIENCES, INC. | SPRB | 87,978 | 87,978 | 2,139,000 | 2,139,000 | $24.31 |
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