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STATE STREET CORP
> ARWR
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 5,507,571 | -462,773 | 196,399,982,000 | -45,757,171,000 | $35,660.00 |
| 12/31/2022 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 5,970,344 | 715,912 | 242,157,153,000 | 241,983,494,000 | $40,560.00 |
| 09/30/2022 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 5,254,432 | -328,314 | 173,659,000 | -22,909,000 | $33.05 |
| 06/30/2022 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 5,582,746 | 900,791 | 196,568,000 | -18,755,000 | $35.21 |
| 03/31/2022 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,681,955 | 777,184 | 215,323,000 | -43,563,000 | $45.99 |
| 12/31/2021 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 3,904,771 | -26,397 | 258,886,000 | 13,463,000 | $66.30 |
| 09/30/2021 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 3,931,168 | 344,837 | 245,423,000 | -51,597,000 | $62.43 |
| 06/30/2021 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 3,586,331 | -147,789 | 297,020,000 | 49,411,000 | $82.82 |
| 03/31/2021 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 3,734,120 | -197,895 | 247,609,000 | -54,095,000 | $66.31 |
| 12/31/2020 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 3,932,015 | -611,109 | 301,704,000 | 106,077,000 | $76.73 |
| 09/30/2020 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,543,124 | -348,323 | 195,627,000 | -15,635,000 | $43.06 |
| 06/30/2020 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,891,447 | 596,773 | 211,262,000 | 87,704,000 | $43.19 |
| 03/31/2020 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,294,674 | 170,204 | 123,558,000 | -138,057,000 | $28.77 |
| 12/31/2019 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,124,470 | -760,166 | 261,615,000 | 123,966,000 | $63.43 |
| 09/30/2019 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,884,636 | 157,101 | 137,649,000 | 12,369,000 | $28.18 |
| 06/30/2019 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,727,535 | 22,938 | 125,280,000 | 38,951,000 | $26.50 |
| 03/31/2019 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,704,597 | -369,178 | 86,329,000 | 23,313,000 | $18.35 |
| 12/31/2018 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 5,073,775 | 139,022 | 63,016,000 | -31,587,000 | $12.42 |
| 09/30/2018 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,934,753 | 902,897 | 94,603,000 | 39,771,000 | $19.17 |
| 06/30/2018 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 4,031,856 | 3,920,185 | 54,832,000 | 54,420,000 | $13.60 |
| 12/31/2017 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 111,671 | 55,031 | 412,000 | 167,000 | $3.69 |
| 09/30/2017 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 56,640 | -10,000 | 245,000 | 138,000 | $4.33 |
| 06/30/2017 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 66,640 | -1,077,026 | 107,000 | -2,008,000 | $1.61 |
| 03/31/2017 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 1,143,666 | 178,638 | 2,115,000 | 619,000 | $1.85 |
| 12/31/2016 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 965,028 | -426,804 | 1,496,000 | -8,737,000 | $1.55 |
| 09/30/2016 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 1,391,832 | 434,296 | 10,233,000 | 5,137,000 | $7.35 |
| 06/30/2016 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 957,536 | 12,676 | 5,096,000 | 545,000 | $5.32 |
| 03/31/2016 | ARROWHEAD PHARMACEUTICALS, INC. | ARWR | 944,860 | 944,860 | 4,551,000 | 4,551,000 | $4.82 |
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