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STATE STREET CORP
> LXRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,730,112 | 213,637 | 3,961,956,000 | 1,065,489,000 | $2,290.00 |
| 12/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,516,475 | 52,906 | 2,896,467,000 | 2,892,954,000 | $1,910.00 |
| 09/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,463,569 | 111,568 | 3,513,000 | 998,000 | $2.40 |
| 06/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,352,001 | 27,616 | 2,515,000 | -253,000 | $1.86 |
| 03/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,324,385 | 109,367 | 2,768,000 | -2,019,000 | $2.09 |
| 12/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,215,018 | 113,265 | 4,787,000 | -512,000 | $3.94 |
| 09/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,101,753 | 64,106 | 5,299,000 | 536,000 | $4.81 |
| 06/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,037,647 | 287,262 | 4,763,000 | 358,000 | $4.59 |
| 03/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 750,385 | 21,791 | 4,405,000 | 1,913,000 | $5.87 |
| 12/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 728,594 | -21,266 | 2,492,000 | 1,412,000 | $3.42 |
| 09/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 749,860 | 3,922 | 1,080,000 | -408,000 | $1.44 |
| 06/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 745,938 | -80,879 | 1,488,000 | -124,000 | $1.99 |
| 03/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 826,817 | -69,353 | 1,612,000 | -2,107,000 | $1.95 |
| 12/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 896,170 | -56,436 | 3,719,000 | 852,000 | $4.15 |
| 09/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 952,606 | 13,654 | 2,867,000 | -3,039,000 | $3.01 |
| 06/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 938,952 | 7,255 | 5,906,000 | 726,000 | $6.29 |
| 03/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 931,697 | -914,801 | 5,180,000 | -7,081,000 | $5.56 |
| 12/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,846,498 | -683,546 | 12,261,000 | -14,733,000 | $6.64 |
| 09/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,530,044 | 529,499 | 26,994,000 | 2,986,000 | $10.67 |
| 06/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,000,545 | -337,489 | 24,008,000 | 907,000 | $12.00 |
| 12/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,338,034 | 243,100 | 23,101,000 | -2,641,000 | $9.88 |
| 09/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,094,934 | 127,679 | 25,742,000 | -6,621,000 | $12.29 |
| 06/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,967,255 | 326,088 | 32,363,000 | 8,827,000 | $16.45 |
| 03/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,641,167 | 49,802 | 23,536,000 | 1,528,000 | $14.34 |
| 12/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,591,365 | 233,371 | 22,008,000 | -2,531,000 | $13.83 |
| 09/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,357,994 | 75,380 | 24,539,000 | 6,133,000 | $18.07 |
| 06/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,282,614 | 73,235 | 18,406,000 | 3,956,000 | $14.35 |
| 03/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,209,379 | -1,270,176 | 14,450,000 | -12,183,000 | $11.95 |
| 12/31/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,399,773 | -1,079,782 | 18,634,000 | -7,999,000 | $13.31 |
| 09/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,479,555 | 1,920,172 | 26,633,000 | 22,129,000 | $10.74 |
| 06/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 559,383 | 559,383 | 4,504,000 | 4,504,000 | $8.05 |
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