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RHUMBLINE ADVISERS
> LXRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | LEXICON PHARMACEUTICALS, INC. | LXRX | 139,747 | 14,681 | 320,025,000 | 319,721,000 | $2,290.03 |
| 03/31/2023 | LEXICON PHARMACEUTICALS, INC. | LXRX | 125,066 | 5,949 | 304,000 | 76,000 | $2.43 |
| 12/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 119,117 | 5,722 | 228,000 | -44,000 | $1.91 |
| 09/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 113,395 | 33,461 | 272,000 | 105,000 | $2.40 |
| 03/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 79,934 | -6,726 | 167,000 | -174,000 | $2.09 |
| 12/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 86,660 | 2,669 | 341,000 | -63,000 | $3.93 |
| 09/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 83,991 | 2,199 | 404,000 | 29,000 | $4.81 |
| 06/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 81,792 | 26,714 | 375,000 | 52,000 | $4.58 |
| 03/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 55,078 | -1,611 | 323,000 | 129,000 | $5.86 |
| 12/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 56,689 | 6,530 | 194,000 | 122,000 | $3.42 |
| 09/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 50,159 | -14,727 | 72,000 | -57,000 | $1.44 |
| 06/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 64,886 | 8,279 | 129,000 | 19,000 | $1.99 |
| 03/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 56,607 | -3,500 | 110,000 | -139,000 | $1.94 |
| 12/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 60,107 | 1,359 | 249,000 | 72,000 | $4.14 |
| 09/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 58,748 | -400 | 177,000 | -195,000 | $3.01 |
| 06/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 59,148 | 3,617 | 372,000 | 63,000 | $6.29 |
| 03/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 55,531 | -1,662 | 309,000 | -71,000 | $5.56 |
| 12/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 57,193 | 18,376 | 380,000 | -34,000 | $6.64 |
| 09/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 38,817 | -2,780 | 414,000 | -85,000 | $10.67 |
| 06/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 41,597 | 1,354 | 499,000 | 154,000 | $12.00 |
| 03/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 40,243 | -1,375 | 345,000 | -66,000 | $8.57 |
| 12/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 41,618 | -9,173 | 411,000 | -213,000 | $9.88 |
| 09/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 50,791 | 1,260 | 624,000 | -191,000 | $12.29 |
| 06/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 49,531 | 2,005 | 815,000 | 133,000 | $16.45 |
| 03/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 47,526 | 1,281 | 682,000 | 42,000 | $14.35 |
| 12/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 46,245 | 3,568 | 640,000 | -131,000 | $13.84 |
| 09/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 42,677 | 700 | 771,000 | 169,000 | $18.07 |
| 06/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 41,977 | 41,977 | 602,000 | 602,000 | $14.34 |
| 03/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 52,903 | 3,455 | 632,000 | -26,000 | $11.95 |
| 12/31/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 49,448 | 2,641 | 658,000 | 281,000 | $13.31 |
| 09/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 47,723 | 916 | 513,000 | 136,000 | $10.75 |
| 06/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 46,807 | 46,807 | 377,000 | 377,000 | $8.05 |
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