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VANGUARD GROUP INC
> ZGEN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2010 | ZYMOGENETICS INC | ZGEN | 2,392,348 | 11,014 | 23,325,000 | 13,276,000 | $9.75 |
| 06/30/2010 | ZYMOGENETICS INC | ZGEN | 2,381,334 | 62,937 | 10,049,000 | -3,235,000 | $4.22 |
| 03/31/2010 | ZYMOGENETICS INC | ZGEN | 2,318,397 | 668,147 | 13,284,000 | 2,739,000 | $5.73 |
| 12/31/2009 | ZYMOGENETICS INC | ZGEN | 1,650,250 | 122,705 | 10,545,000 | 1,319,000 | $6.39 |
| 09/30/2009 | ZYMOGENETICS INC | ZGEN | 1,527,545 | 49,192 | 9,226,000 | 2,760,000 | $6.04 |
| 06/30/2009 | ZYMOGENETICS INC | ZGEN | 1,478,353 | 10,706 | 6,466,000 | 610,000 | $4.37 |
| 03/31/2009 | ZYMOGENETICS INC | ZGEN | 1,467,647 | 92,317 | 5,856,000 | 1,730,000 | $3.99 |
| 12/31/2008 | ZYMOGENETICS INC | ZGEN | 1,375,330 | 121,110 | 4,126,000 | -4,227,000 | $3.00 |
| 09/30/2008 | ZYMOGENETICS INC | ZGEN | 1,254,220 | 1,244,723 | 8,353,000 | 7,225,158 | $6.66 |
| 06/30/2008 | ZYMOGENETICS INC | ZGEN | 9,497 | -319 | 1,127,842 | 126,214 | $118.76 |
| 03/31/2008 | ZYMOGENETICS INC | ZGEN | 9,816 | 9,816 | 1,001,628 | 1,001,628 | $102.04 |
| 12/31/2007 | ZYMOGENETICS INC | ZGEN | 11,260 | 11,260 | 964,798 | 964,798 | $85.68 |
| 03/31/2002 | ZYMOGENETICS INC | ZGEN | 1,608 | 1,608 | 142,467 | 142,467 | $88.57 |
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