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UBS Group AG
> SPRO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Spero Therapeutics, Inc. | SPRO | 27,071 | -14,452 | 39,253,000 | -20,956,000 | $1,450.00 |
| 03/31/2023 | Spero Therapeutics, Inc. | SPRO | 41,523 | -4,159 | 60,209,000 | -18,822,000 | $1,450.02 |
| 12/31/2022 | Spero Therapeutics, Inc. | SPRO | 45,682 | 22,774 | 79,031,000 | 78,985,000 | $1,730.02 |
| 09/30/2022 | Spero Therapeutics, Inc. | SPRO | 22,908 | 22,153 | 46,000 | 45,000 | $2.01 |
| 06/30/2022 | Spero Therapeutics, Inc. | SPRO | 755 | 0 | 1,000 | -6,000 | $1.32 |
| 03/31/2022 | Spero Therapeutics, Inc. | SPRO | 755 | -32,327 | 7,000 | -522,000 | $9.27 |
| 12/31/2021 | Spero Therapeutics, Inc. | SPRO | 33,082 | 4,260 | 529,000 | -1,000 | $15.99 |
| 09/30/2021 | Spero Therapeutics, Inc. | SPRO | 28,822 | 26,929 | 530,000 | 503,000 | $18.39 |
| 06/30/2021 | Spero Therapeutics, Inc. | SPRO | 1,893 | -12,454 | 27,000 | -251,000 | $14.26 |
| 12/31/2020 | Spero Therapeutics, Inc. | SPRO | 14,347 | 13,847 | 278,000 | 272,000 | $19.38 |
| 09/30/2020 | Spero Therapeutics, Inc. | SPRO | 500 | -5,452 | 6,000 | -74,000 | $12.00 |
| 06/30/2020 | Spero Therapeutics, Inc. | SPRO | 5,952 | -3,041 | 80,000 | 7,000 | $13.44 |
| 03/31/2020 | Spero Therapeutics, Inc. | SPRO | 8,993 | -5,274 | 73,000 | -64,000 | $8.12 |
| 12/31/2019 | Spero Therapeutics, Inc. | SPRO | 14,267 | 3,216 | 137,000 | 20,000 | $9.60 |
| 09/30/2019 | Spero Therapeutics, Inc. | SPRO | 11,051 | -751 | 117,000 | -19,000 | $10.59 |
| 06/30/2019 | Spero Therapeutics, Inc. | SPRO | 11,802 | 11,802 | 136,000 | 136,000 | $11.52 |
| 03/31/2019 | Spero Therapeutics, Inc. | SPRO | 0 | -3,200 | 0 | -20,000 | |
| 12/31/2018 | Spero Therapeutics, Inc. | SPRO | 3,200 | 841 | 20,000 | -5,000 | $6.25 |
| 09/30/2018 | Spero Therapeutics, Inc. | SPRO | 2,359 | 1,414 | 25,000 | 12,000 | $10.60 |
| 06/30/2018 | Spero Therapeutics, Inc. | SPRO | 945 | 817 | 13,000 | 12,000 | $13.76 |
| 12/31/2017 | Spero Therapeutics, Inc. | SPRO | 128 | 128 | 1,000 | 1,000 | $7.81 |
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