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Rock Springs Capital Management LP
> SPRB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 2,728,125 | 0 | 5,865,469,000 | -163,687,000 | $2,150.00 |
| 03/31/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 2,728,125 | 1,105,436 | 6,029,156,000 | 4,248,417,000 | $2,210.00 |
| 12/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,622,689 | 0 | 1,780,739,000 | 1,778,516,000 | $1,097.40 |
| 09/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,622,689 | 0 | 2,223,000 | -600,000 | $1.37 |
| 06/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,622,689 | 0 | 2,823,000 | -439,000 | $1.74 |
| 03/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,622,689 | 0 | 3,262,000 | -3,975,000 | $2.01 |
| 12/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,622,689 | 5,088 | 7,237,193 | -2,484,807 | $4.46 |
| 09/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,617,601 | 12,600 | 9,722,000 | -8,270,000 | $6.01 |
| 06/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,605,001 | 25,700 | 17,992,000 | -8,224,000 | $11.21 |
| 03/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,579,301 | -51,699 | 26,216,000 | -13,434,000 | $16.60 |
| 12/31/2020 | SPRUCE BIOSCIENCES, INC. | SPRB | 1,631,000 | 1,631,000 | 39,650,000 | 39,650,000 | $24.31 |
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