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Rock Springs Capital Management LP
> RYTM
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 1,597,123 | 0 | 26,336,558,000 | -2,156,116,000 | $16,490.00 |
| 03/31/2023 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 1,597,123 | -163,742 | 28,492,674,000 | -22,783,715,000 | $17,840.00 |
| 12/31/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 1,760,865 | 0 | 51,276,389,000 | 51,233,248,000 | $29,120.00 |
| 09/30/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 1,760,865 | 357,567 | 43,141,000 | 37,317,000 | $24.50 |
| 06/30/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 1,403,298 | 166,272 | 5,824,000 | -8,427,000 | $4.15 |
| 03/31/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 1,237,026 | 609,846 | 14,251,000 | 7,992,000 | $11.52 |
| 12/31/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 627,180 | 15,000 | 6,259,000 | -1,736,000 | $9.98 |
| 09/30/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 612,180 | 5,900 | 7,995,000 | -3,876,000 | $13.06 |
| 06/30/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 606,280 | 7,000 | 11,871,000 | -876,000 | $19.58 |
| 03/31/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 599,280 | 108,941 | 12,747,000 | -1,831,000 | $21.27 |
| 12/31/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 490,339 | 26,253 | 14,578,000 | 4,521,000 | $29.73 |
| 09/30/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 464,086 | -48,025 | 10,057,000 | -1,363,000 | $21.67 |
| 06/30/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 512,111 | 12,111 | 11,420,000 | 3,810,000 | $22.30 |
| 03/31/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 500,000 | 155,000 | 7,610,000 | -311,000 | $15.22 |
| 12/31/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 345,000 | 40,000 | 7,921,000 | 1,336,000 | $22.96 |
| 09/30/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 305,000 | 70,000 | 6,585,000 | 1,415,000 | $21.59 |
| 06/30/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 235,000 | 18,500 | 5,170,000 | -764,000 | $22.00 |
| 03/31/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 216,500 | 0 | 5,934,000 | 114,000 | $27.41 |
| 12/31/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 216,500 | 1,500 | 5,820,000 | -452,000 | $26.88 |
| 09/30/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 215,000 | 0 | 6,272,000 | -449,000 | $29.17 |
| 06/30/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 215,000 | 143,500 | 6,721,000 | 5,298,000 | $31.26 |
| 03/31/2018 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 71,500 | 0 | 1,423,000 | -655,000 | $19.90 |
| 12/31/2017 | RHYTHM PHARMACEUTICALS, INC. | RYTM | 71,500 | 71,500 | 2,078,000 | 2,078,000 | $29.06 |
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