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Rock Springs Capital Management LP
> AGLE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Aeglea BioTherapeutics, Inc. | AGLE | 3,413,906 | 0 | 1,537,965,000 | 547,932,000 | $450.50 |
| 03/31/2023 | Aeglea BioTherapeutics, Inc. | AGLE | 3,413,906 | 0 | 990,033,000 | -545,883,000 | $290.00 |
| 12/31/2022 | Aeglea BioTherapeutics, Inc. | AGLE | 3,413,906 | 0 | 1,535,916,000 | 1,534,120,000 | $449.90 |
| 09/30/2022 | Aeglea BioTherapeutics, Inc. | AGLE | 3,413,906 | 341,872 | 1,796,000 | 244,000 | $0.53 |
| 06/30/2022 | Aeglea BioTherapeutics, Inc. | AGLE | 3,072,034 | 1,260,609 | 1,552,000 | -2,614,000 | $0.51 |
| 03/31/2022 | Aeglea BioTherapeutics, Inc. | AGLE | 1,811,425 | 234,129 | 4,166,000 | -3,326,000 | $2.30 |
| 12/31/2021 | Aeglea BioTherapeutics, Inc. | AGLE | 1,577,296 | 0 | 7,492,000 | -5,048,000 | $4.75 |
| 09/30/2021 | Aeglea BioTherapeutics, Inc. | AGLE | 1,577,296 | 0 | 12,540,000 | 1,562,000 | $7.95 |
| 06/30/2021 | Aeglea BioTherapeutics, Inc. | AGLE | 1,577,296 | 0 | 10,978,000 | -1,514,000 | $6.96 |
| 03/31/2021 | Aeglea BioTherapeutics, Inc. | AGLE | 1,577,296 | -2,704 | 12,492,000 | 57,000 | $7.92 |
| 12/31/2020 | Aeglea BioTherapeutics, Inc. | AGLE | 1,580,000 | -10,528 | 12,435,000 | 1,158,000 | $7.87 |
| 09/30/2020 | Aeglea BioTherapeutics, Inc. | AGLE | 1,590,528 | 0 | 11,277,000 | -3,435,000 | $7.09 |
| 06/30/2020 | Aeglea BioTherapeutics, Inc. | AGLE | 1,590,528 | 790,528 | 14,712,000 | 10,984,000 | $9.25 |
| 03/31/2020 | Aeglea BioTherapeutics, Inc. | AGLE | 800,000 | 0 | 3,728,000 | -2,384,000 | $4.66 |
| 12/31/2019 | Aeglea BioTherapeutics, Inc. | AGLE | 800,000 | 0 | 6,112,000 | -40,000 | $7.64 |
| 09/30/2019 | Aeglea BioTherapeutics, Inc. | AGLE | 800,000 | 0 | 6,152,000 | 672,000 | $7.69 |
| 06/30/2019 | Aeglea BioTherapeutics, Inc. | AGLE | 800,000 | 0 | 5,480,000 | -960,000 | $6.85 |
| 03/31/2019 | Aeglea BioTherapeutics, Inc. | AGLE | 800,000 | 150,000 | 6,440,000 | 1,571,000 | $8.05 |
| 12/31/2018 | Aeglea BioTherapeutics, Inc. | AGLE | 650,000 | 0 | 4,869,000 | -1,352,000 | $7.49 |
| 09/30/2018 | Aeglea BioTherapeutics, Inc. | AGLE | 650,000 | 0 | 6,221,000 | -656,000 | $9.57 |
| 06/30/2018 | Aeglea BioTherapeutics, Inc. | AGLE | 650,000 | 125,911 | 6,877,000 | 1,678,000 | $10.58 |
| 03/31/2018 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 0 | 5,199,000 | 2,364,000 | $9.92 |
| 12/31/2017 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 0 | 2,835,000 | 251,000 | $5.41 |
| 09/30/2017 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 0 | 2,584,000 | 571,000 | $4.93 |
| 06/30/2017 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 0 | 2,013,000 | -1,891,000 | $3.84 |
| 03/31/2017 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 0 | 3,904,000 | 1,624,000 | $7.45 |
| 12/31/2016 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 0 | 2,280,000 | -1,079,000 | $4.35 |
| 09/30/2016 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 0 | 3,359,000 | 812,000 | $6.41 |
| 06/30/2016 | Aeglea BioTherapeutics, Inc. | AGLE | 524,089 | 524,089 | 2,547,000 | 2,547,000 | $4.86 |
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