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COLUMBIA PARTNERS L L C INVESTMENT MANAGEMENT
> LGND
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2018 | LIGAND PHARMACEUTICALS INC | LGND | 11,108 | 5,767 | 1,507,000 | 41,000 | $135.67 |
| 09/30/2018 | LIGAND PHARMACEUTICALS INC | LGND | 5,341 | 5,341 | 1,466,000 | 1,466,000 | $274.48 |
| 06/30/2018 | LIGAND PHARMACEUTICALS INC | LGND | 0 | -2,887 | 0 | -476,000 | |
| 03/31/2018 | LIGAND PHARMACEUTICALS INC | LGND | 2,887 | -4,500 | 476,000 | -535,000 | $164.88 |
| 12/31/2017 | LIGAND PHARMACEUTICALS INC | LGND | 7,387 | -2,998 | 1,011,000 | -402,000 | $136.86 |
| 09/30/2017 | LIGAND PHARMACEUTICALS INC | LGND | 10,385 | 4,502 | 1,413,000 | 699,000 | $136.06 |
| 06/30/2017 | LIGAND PHARMACEUTICALS INC | LGND | 5,883 | -13,003 | 714,000 | -1,284,000 | $121.37 |
| 03/31/2017 | LIGAND PHARMACEUTICALS INC | LGND | 18,886 | -38,272 | 1,998,000 | -3,809,000 | $105.79 |
| 12/31/2016 | LIGAND PHARMACEUTICALS INC | LGND | 57,158 | -11,519 | 5,807,000 | -1,202,000 | $101.60 |
| 09/30/2016 | LIGAND PHARMACEUTICALS INC | LGND | 68,677 | 23,921 | 7,009,000 | 1,671,000 | $102.06 |
| 06/30/2016 | LIGAND PHARMACEUTICALS INC | LGND | 44,756 | 23,189 | 5,338,000 | 3,000,000 | $119.27 |
| 03/31/2016 | LIGAND PHARMACEUTICALS INC | LGND | 44,838 | 23,271 | 4,801,000 | 2,463,000 | $107.07 |
| 12/31/2015 | LIGAND PHARMACEUTICALS INC | LGND | 21,567 | 21,567 | 2,338,000 | 2,338,000 | $108.41 |
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