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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2009 | ZYMOGENETICS INC | ZGEN | 244,059 | 231,935 | 1,474,000 | 1,418,000 | $6.04 |
| 06/30/2009 | ZYMOGENETICS INC | ZGEN | 12,124 | 10,727 | 56,000 | 50,000 | $4.62 |
| 03/31/2009 | ZYMOGENETICS INC | ZGEN | 1,397 | -180 | 6,000 | 1,000 | $4.29 |
| 12/31/2008 | ZYMOGENETICS INC | ZGEN | 1,577 | -22,729 | 5,000 | -157,000 | $3.17 |
| 09/30/2008 | ZYMOGENETICS INC | ZGEN | 24,306 | 4,626 | 162,000 | -31,000 | $6.67 |
| 06/30/2008 | ZYMOGENETICS INC | ZGEN | 19,680 | 2,565 | 193,000 | 25,000 | $9.81 |
| 03/31/2008 | ZYMOGENETICS INC | ZGEN | 17,115 | -85,302 | 168,000 | -1,027,206 | $9.82 |
| 12/31/2007 | ZYMOGENETICS INC | ZGEN | 102,417 | -169,110 | 1,195,206 | -2,348,221 | $11.67 |
| 09/30/2007 | ZYMOGENETICS INC | ZGEN | 271,527 | 271,527 | 3,543,427 | 3,543,427 | $13.05 |
| 03/31/2007 | ZYMOGENETICS INC | ZGEN | 0 | -75,931 | 0 | -1,182,246 | |
| 12/31/2006 | ZYMOGENETICS INC | ZGEN | 75,931 | 75,931 | 1,182,246 | 1,182,246 | $15.57 |
| 03/31/2006 | ZYMOGENETICS INC | ZGEN | 0 | -110,701 | 0 | -1,883,024 | |
| 12/31/2005 | ZYMOGENETICS INC | ZGEN | 110,701 | 67,872 | 1,883,024 | 1,176,345 | $17.01 |
| 09/30/2005 | ZYMOGENETICS INC | ZGEN | 42,829 | 42,829 | 706,679 | 706,679 | $16.50 |
| 06/30/2005 | ZYMOGENETICS INC | ZGEN | 0 | -13,125 | 0 | -200,288 | |
| 03/31/2005 | ZYMOGENETICS INC | ZGEN | 13,125 | -10,467 | 200,288 | -342,328 | $15.26 |
| 12/31/2004 | ZYMOGENETICS INC | ZGEN | 23,592 | 164 | 542,616 | 134,032 | $23.00 |
| 09/30/2004 | ZYMOGENETICS INC | ZGEN | 23,428 | 23,428 | 408,584 | 408,584 | $17.44 |
| 06/30/2004 | ZYMOGENETICS INC | ZGEN | 0 | -100,000 | 0 | -1,546,000 | |
| 03/31/2004 | ZYMOGENETICS INC | ZGEN | 100,000 | 0 | 1,546,000 | -4,000 | $15.46 |
| 12/31/2003 | ZYMOGENETICS INC | ZGEN | 100,000 | 100,000 | 1,550,000 | 1,550,000 | $15.50 |
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