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GOLDMAN SACHS GROUP INC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,711,731 | -9,016 | 539,315,261,000 | 538,817,035,000 | $315,070.10 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,720,747 | 673,107 | 498,226,000 | 203,012,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,047,640 | -139,737 | 295,214,000 | 34,468,000 | $281.79 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,187,377 | -206,385 | 260,746,000 | 7,931,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,393,762 | 15,745 | 252,815,000 | -25,034,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,378,017 | -182,629 | 277,849,000 | -90,993,000 | $201.63 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,560,646 | -483,081 | 368,842,000 | -187,298,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,043,727 | 543,029 | 556,140,000 | 120,472,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,500,698 | -252,282 | 435,668,000 | 18,548,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,752,980 | -115,419 | 417,120,000 | 8,034,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,868,399 | 259,060 | 409,086,000 | 136,433,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,609,339 | -350,181 | 272,653,000 | -86,684,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,959,520 | -342,113 | 359,337,000 | -64,048,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,301,633 | -244,307 | 423,385,000 | 1,497,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,545,940 | -59,559 | 421,888,000 | -80,295,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,605,499 | -746,306 | 502,183,000 | -67,489,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,351,805 | 121,604 | 569,672,000 | 85,594,000 | $169.96 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,230,201 | 533,497 | 484,078,000 | 74,072,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,696,704 | -82,840 | 410,006,000 | 51,805,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,779,544 | 5,904 | 358,201,000 | 54,903,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,773,640 | -256,947 | 303,298,000 | 80,035,000 | $109.35 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,030,587 | 436,688 | 223,263,000 | -2,951,000 | $73.67 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,593,899 | 2,593,899 | 226,214,000 | 226,214,000 | $87.21 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,898,682 | -771,214 | 249,345,000 | -42,375,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,669,896 | 1,545,697 | 291,720,000 | 24,432,000 | $79.49 |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,124,199 | 128,236 | 267,288,000 | 59,428,000 | $125.83 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,995,963 | 1,029,143 | 207,860,000 | 88,477,000 | $104.14 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 966,820 | -9,568 | 119,383,000 | 4,199,000 | $123.48 |
| 03/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 976,388 | -4,558,450 | 115,184,000 | -327,935,000 | $117.97 |
| 12/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 959,056 | -430,629 | 113,936,000 | -42,140,000 | $118.80 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,389,685 | -592,915 | 156,076,000 | -31,636,000 | $112.31 |
| 06/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,982,600 | -1,097,110 | 187,712,000 | -30,085,000 | $94.68 |
| 03/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,079,710 | -685,988 | 217,797,000 | -61,994,000 | $70.72 |
| 12/31/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,765,698 | -1,376,934 | 279,791,000 | -110,123,000 | $74.30 |
| 09/30/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 5,142,632 | -392,206 | 389,914,000 | -53,205,000 | $75.82 |
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