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ALLIANCEBERNSTEIN L.P.
> LXRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | LEXICON PHARMACEUTICALS, INC. | LXRX | 227,111 | 133,700 | 520,084,000 | 293,095,000 | $2,290.00 |
| 03/31/2023 | LEXICON PHARMACEUTICALS, INC. | LXRX | 93,411 | 3,600 | 226,989,000 | 55,450,000 | $2,430.00 |
| 12/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 89,811 | 4,800 | 171,539,000 | 171,335,000 | $1,910.00 |
| 09/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 85,011 | 28,400 | 204,000 | 99,000 | $2.40 |
| 06/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 56,611 | 6,200 | 105,000 | 0 | $1.85 |
| 03/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 50,411 | 300 | 105,000 | -92,000 | $2.08 |
| 12/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 50,111 | 0 | 197,000 | -44,000 | $3.93 |
| 09/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 50,111 | -6,000 | 241,000 | -17,000 | $4.81 |
| 06/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 56,111 | 12,000 | 258,000 | -1,000 | $4.60 |
| 03/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 44,111 | -14,500 | 259,000 | 59,000 | $5.87 |
| 12/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 58,611 | -51,442 | 200,000 | 42,000 | $3.41 |
| 09/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 110,053 | -71,700 | 158,000 | -205,000 | $1.44 |
| 06/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 181,753 | 39,950 | 363,000 | 86,000 | $2.00 |
| 03/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 141,803 | 43,300 | 277,000 | -132,000 | $1.95 |
| 12/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 98,503 | 0 | 409,000 | 113,000 | $4.15 |
| 09/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 98,503 | 0 | 296,000 | -324,000 | $3.00 |
| 06/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 98,503 | 18,200 | 620,000 | 174,000 | $6.29 |
| 03/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 80,303 | -9,000 | 446,000 | -147,000 | $5.55 |
| 12/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 89,303 | 6,100 | 593,000 | -295,000 | $6.64 |
| 09/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 83,203 | -179 | 888,000 | -113,000 | $10.67 |
| 06/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 83,382 | 8,900 | 1,001,000 | 363,000 | $12.00 |
| 03/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 74,482 | 0 | 638,000 | -98,000 | $8.57 |
| 12/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 74,482 | -107,300 | 736,000 | -1,498,000 | $9.88 |
| 09/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 181,782 | 100,000 | 2,234,000 | 889,000 | $12.29 |
| 06/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 81,782 | -107,710 | 1,345,000 | -1,372,000 | $16.45 |
| 03/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 189,492 | -1,080 | 2,717,000 | 81,000 | $14.34 |
| 12/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 190,572 | -14,970 | 2,636,000 | -1,078,000 | $13.83 |
| 09/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 205,542 | 205,542 | 3,714,000 | 3,714,000 | $18.07 |
| 06/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 143,260 | 143,260 | 2,056,000 | 2,056,000 | $14.35 |
| 03/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 63,680 | -671 | 761,000 | -96,000 | $11.95 |
| 12/31/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 64,351 | 64,351 | 857,000 | 857,000 | $13.32 |
| 09/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 76,101 | 76,101 | 817,000 | 817,000 | $10.74 |
| 06/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 80,989 | 80,989 | 652,000 | 652,000 | $8.05 |
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