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PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO
> ISTA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2012 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 159,000 | 35,000 | $9.03 |
| 12/31/2011 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | -104,500 | 124,000 | -297,000 | $7.05 |
| 09/30/2011 | ISTA PHARMACEUTICALS INC | ISTA | 122,100 | 0 | 421,000 | -512,000 | $3.45 |
| 06/30/2011 | ISTA PHARMACEUTICALS INC | ISTA | 122,100 | 104,500 | 933,000 | 755,000 | $7.64 |
| 03/31/2011 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 178,000 | 88,000 | $10.11 |
| 12/31/2010 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 90,000 | 18,000 | $5.11 |
| 09/30/2010 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 72,000 | 33,000 | $4.09 |
| 06/30/2010 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 39,000 | -33,000 | $2.22 |
| 03/31/2010 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 72,000 | -8,000 | $4.09 |
| 12/31/2009 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 80,000 | 2,000 | $4.55 |
| 09/30/2009 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 78,000 | 4,000 | $4.43 |
| 06/30/2009 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 74,000 | 43,000 | $4.20 |
| 03/31/2009 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 31,000 | 18,000 | $1.76 |
| 12/31/2008 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 13,000 | -15,000 | $0.74 |
| 09/30/2008 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 28,000 | -8,000 | $1.59 |
| 06/30/2008 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 36,000 | 2,000 | $2.05 |
| 03/31/2008 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 34,000 | -52,000 | $1.93 |
| 12/31/2007 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 86,000 | -35,000 | $4.89 |
| 09/30/2007 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 121,000 | -9,000 | $6.88 |
| 06/30/2007 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 130,000 | -19,000 | $7.39 |
| 03/31/2007 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 149,000 | 24,000 | $8.47 |
| 12/31/2006 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 125,000 | 21,000 | $7.10 |
| 09/30/2006 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 104,000 | -23,000 | $5.91 |
| 06/30/2006 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 127,000 | 15,000 | $7.22 |
| 03/31/2006 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 112,000 | 0 | $6.36 |
| 12/31/2005 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 112,000 | -5,000 | $6.36 |
| 09/30/2005 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 117,000 | -29,000 | $6.65 |
| 06/30/2005 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 146,000 | -28,000 | $8.30 |
| 03/31/2005 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 174,000 | -4,000 | $9.89 |
| 12/31/2004 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 178,000 | -37,000 | $10.11 |
| 09/30/2004 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 0 | 215,000 | 31,000 | $12.22 |
| 06/30/2004 | ISTA PHARMACEUTICALS INC | ISTA | 17,600 | 7,200 | 184,000 | 50,000 | $10.45 |
| 03/31/2004 | ISTA PHARMACEUTICALS INC | ISTA | 10,400 | 10,400 | 134,000 | 134,000 | $12.88 |
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